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2

项与 Pinnacle Health System LLC 相关的临床试验

NCT00964444

/ CompletedN/A

Demonstration of a New Device to Measure the Force of Delivering a Baby

This study is an observational study to prove that a new device, which measures the force of delivering a baby, (US patent 6,684,165) functions as described in the patent. This is the first time this has been used with patients.

开始日期2009-04-01

申办/合作机构

Pinnacle Health System LLC

NCT00508976

/ Completed临床2期

Evaluation of Aerosolized Bupivacaine Versus Pre-incision Lidocaine Versus Instilled Liquid Bupivacaine Versus Post-operative Bupivacaine Injection for Optimization of Post-operative Pain Control in Laparoscopic Bariatric Surgical Patients

The purpose of this study is to determine if pre-incisional lidocaine injection, instilled liquid bupivacaine, intra-abdominal aerosolized bupivacaine, or post-operative bupivacaine injection is superior in post-operative pain control in laparoscopic bariatric surgical patients.

开始日期2007-06-01

申办/合作机构

Pinnacle Health System LLC

100 项与 Pinnacle Health System LLC 相关的临床结果

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0 项与 Pinnacle Health System LLC 相关的专利（医药）

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3

项与 Pinnacle Health System LLC 相关的文献（医药）

2010-09-01·American Heart Journal2区 · 医学

Low-molecular-weight heparin versus unfractionated heparin in acute ST-segment elevation myocardial infarction patients undergoing primary percutaneous coronary intervention with drug-eluting stents

2区 · 医学

Letter

作者: Anusionwu, Obiora F. ; Shah, Nirav

A polemic in response to Li et al. (American Heart Journal, 2010, 159, pp. 684-690 e1) is presented.Li et al. reported that low-mol.-weight heparin combined with a reduced dose of unfractionated heparin (UFH) when administered as an adjunct in ST-segment elevation myocardial infarction patients undergoing percutaneous coronary intervention (PCI) with drug-eluting stents seems to be safe and efficacious.Yet, several factors belie this conclusion.The dose adjustment of antithrombotics was left to the discretion of the individual physician, resulting in some patients receiving 24,000 U/d of UFH for more than 2 days.This could affect in-hospital outcomes.

2010-06-01·Circulation: Cardiovascular Interventions1区 · 医学

Nitinol Stent Implantation Versus Balloon Angioplasty for Lesions in the Superficial Femoral Artery and Proximal Popliteal Artery

1区 · 医学

Article

作者: Collins, Tyrone J. ; Buchbinder, Maurice ; Scheinert, Dierk ; Lammer, Johannes ; Cristea, Ecaterina ; Ansel, Gary ; Carpenter, Jeffrey ; Dave, Rajesh ; Lansky, Alexandra ; Jaff, Michael R. ; Laird, John R. ; Goldstein, Jeffrey ; Katzen, Barry T.

Background—Controversy still exists regarding the best endovascular treatment strategy for patients with symptomatic disease of the superficial femoral artery. There are conflicting data regarding the benefits of superficial femoral artery stenting and the role of primary stenting compared with balloon angioplasty with provisional stent implantation.Methods and Results— A total of 206 patients from 24 centers in the United States and Europe with obstructive lesions of the superficial femoral artery and proximal popliteal artery and intermittent claudication were randomized to implantation of nitinol stents or percutaneous transluminal angioplasty. The mean total lesion length was 71 mm for the stent group and 64 mm for the angioplasty group. Acute lesion success (<30%residual stenosis) was superior for the stent group compared with the angioplasty group (95.8% versus 83.9%; P <0.01). Twenty-nine (40.3%) patients in the angioplasty group underwent bailout stenting because of a suboptimal angiographic result or flow-limiting dissection. Bailout stenting was treated as a target lesion revascularization and loss of primary patency in the final analysis. At 12 months, freedom from target lesion revascularization was 87.3% for the stent group compared with 45.1% for the angioplasty group ( P <0.0001). Duplex ultrasound-derived primary patency at 12 months was better for the stent group (81.3% versus 36.7%; P <0.0001). Through 12 months, fractures occurred in 3.1% of stents implanted. No stent fractures resulted in loss of patency or target lesion revascularization. Conclusions—In this multicenter trial, primary implantation of a self-expanding nitinol stent for moderate-length lesions in the superficial femoral artery and proximal popliteal artery was associated with better acute angiographic results and improved patency compared with balloon angioplasty alone.Clinical Trial Registration— URL: http://www.clinicaltrials.gov . Unique identifier: NCT00673985.

Nature Medicine (New York)

Osler′s Web inside the labyrinth of the chronic fatigue syndrome epidemic by Hillary Johnson

作者: Gantz, Nelson M.

100 项与 Pinnacle Health System LLC 相关的药物交易

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100 项与 Pinnacle Health System LLC 相关的转化医学

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