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2

项与 Wagner Macula & Retina Center 相关的临床试验

NCT04300881 / Terminated临床2期IIT

Treatment of Post-Ocriplasmin Therapy Vitreolysis Induced Subretinal Fluid With Eplerenone (Mineralocorticoid Antagonists): The TOTEM Study

Evaluate the efficacy of eplerenone as an adjunctive treatment to intravitreal ocriplasmin for subretinal fluid in comparison to a control group of only receiving intravitreal ocriplasmin in patients with symptomatic vitreomacular adhesion.

开始日期2019-10-04

申办/合作机构

Wagner Macula & Retina Center

[+1]

NCT03423823 / Completed临床2期IIT

An Active-treatment Study of the Efficacy of Ziv-aflibercept in Patients With Neovascular Age-Related Macular Degeneration

This is a randomized, open-label, interventional, controlled study to determine the effects of Zaltrap on Neovascularized Wet Macular Degeneration as compared to the control anti-vascular endothelial growth factor ("anti-VEGF") injections (bevacizumab, ranibizumab, or aflibercept).

开始日期2017-07-07

申办/合作机构

Wagner Macula & Retina Center

100 项与 Wagner Macula & Retina Center 相关的临床结果

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0 项与 Wagner Macula & Retina Center 相关的专利（医药）

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15

项与 Wagner Macula & Retina Center 相关的文献（医药）

2023-02-01·Ophthalmology Retina

The Predictive Value of False-Positive ForeseeHome Alerts in the ALOFT Study

Article

作者: Chew, Emily Y ; Wagner, Allen L ; Mathai, Mariam ; Jacobs, Jennifer H ; Garfinkel, Richard A ; Sanborn, George E ; Busquets, Miguel A ; Schechet, Sidney A ; Ho, Allen C ; Ladd, Byron ; Elman, Michael J ; Reddy, Shivani

2022-10-01·Ophthalmology Retina

Analysis of the Long-term Visual Outcomes of ForeseeHome Remote Telemonitoring

Review

作者: Jacobs, Jennifer H ; Busquets, Miguel A ; Reddy, Shivani ; Mathai, Mariam ; Sanborn, George E ; Ladd, Byron ; Wagner, Alan L ; Garfinkel, Richard A ; Elman, Michael J ; Chew, Emily Y

PURPOSETo evaluate long-term visual acuity (VA) and performance of a monitoring strategy with a self-operated artificial-intelligence-enabled home monitoring system in conjunction with standard care for early detection of neovascular age-related macular degeneration (nAMD).DESIGNRetrospective review.SUBJECTSPatients with dry-age-related macular degeneration from 5 referral clinics.METHODSClinical data of patients monitored with ForeseeHome (FSH) device from August 2010 to July 2020 were reviewed.MAIN OUTCOME MEASURESVisual acuity at baseline, VA at diagnosis of nAMD for eyes that converted while monitored, and VA from the final study follow-up, weekly frequency of use, duration of monitoring, modality of conversion diagnosis (system alert vs. detection by other standard care means), and duration and number of treatments since conversion to final study follow-up were collected.RESULTSWe reviewed 3334 eyes of 2123 patients with a mean (standard deviation [SD]) age of 74(8) years, monitored for a mean (SD) duration of 3.1 (2.4) years, with a total of 1 706 433 tests in 10 474 eye-monitoring years. The mean (SD) weekly use per patient was 5.2 (3.4), and it was persistent over the usage period. Two hundred eighty-five eyes converted while monitored at an annual rate of 2.72% and were treated with a mean (SD) 17.3 (16.5) injections over a mean (SD) 2.7 (2.0) years, with 6.4 (3.1) injections per year for eyes treated for > 1 year. The median VAs at baseline and at final follow-up for eyes that did not convert were 20/27 and 20/34 with a median change of 0.0 letters. The median VAs at baseline, conversion, and final follow-up for eyes that converted during the monitoring period were 20/30, 20/39, and 20/32 with a median change from baseline to conversion, baseline to recent, and conversion to recent of -4, -4, and 0 letters, respectively. Fifty-two percent of conversions detected had a system alert before conversion. Forty-eight percent of patients were detected by symptoms or routine visit. Patients experienced a non-nAMD alert on average every 4.6 years. At conversion and at final follow-up, the proportion (95% CI) of eyes that maintained ≥ 20/40 was 84% (78% to 88%) and 82% (76% to 86%), respectively.CONCLUSIONSPatients in the FSH monitoring program showed excellent long-term VA years after conversion to nAMD.

2021-12-01·Journal of the American Academy of Dermatology1区 · 医学

Peripheral retinal vascular leakage in moderate to severe psoriasis: A pilot study

1区 · 医学

Letter

作者: Enos, Clinton W ; Van Voorhees, Abby S ; Kapoor, Kapil G ; Wagner, Alan L

100 项与 Wagner Macula & Retina Center 相关的药物交易

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100 项与 Wagner Macula & Retina Center 相关的转化医学

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