Delving into the Latest Updates on Cosar Pharm Co. with Synapse

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项与 Cosar Pharm Co. 相关的临床试验

IRCT20180620040164N64 / Suspended

Bioequivalence study of empagliflozin+ Linagliptin 25+ 5 mg of Cosar company in comparison with the reference sample of Glyxambi made by Boehringer company.

开始日期2024-09-10

申办/合作机构

Cosar Pharm Co.

IRCT20180620040164N63 / Suspended

Bioequivalence study of empagliflozin 25 mg of Cosar Pharmaceutical Co. in comparison with the reference sample of Jardiance made by Boehringer company.

开始日期2024-09-10

申办/合作机构

Cosar Pharm Co.

IRCT20180620040164N69 / Suspended

Bioequivalence study of empagliflozin+ Linagliptin 10+ 5 mg of Cosar company in comparison with the reference sample of Glyxambi made by Boehringer company.

开始日期2024-08-27

申办/合作机构

Cosar Pharm Co.

100 项与 Cosar Pharm Co. 相关的临床结果

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0 项与 Cosar Pharm Co. 相关的专利（医药）

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1

项与 Cosar Pharm Co. 相关的文献（医药）

2006-09-01·Journal of Bioactive and Compatible Polymers

Synthesis of N, N-dimethyl N-ethyl Chitosan as a Carrier for Oral Delivery of Peptide Drugs

作者: Amini, M. ; Majlesi, R. ; Shafiee, A. ; Avadi, M. R. ; Sadeghi, A. M.M. ; Bayat, A. ; Junginger, H. E. ; Rafiee-Tehrani, M.

N, N-dimethyl N-ethyl chitosan (DMEC), a quanternized derivative of chitosan was synthesized based on a modified two-step method via a 22 factorial design to optimize the preparative conditions. The degree of deacetylation of the starting chitosan was determined by FTIR and NMR methods and was 95%. In the first step of the synthesis, mono-ethyl chitosan was prepared by introducing an ethyl group onto the amine group of chitosan via a Schiff base and in the next step methyl iodide was added to produce DMEC which was water soluble in a pH range of 4-8. The DMEC polymers with different degrees of quaternization were obtained and fully characterized using FTIR and 1H-NMR spectroscopic methods. Based on 1H-NMR calculations, the degree of quaternization was 52% by optimizing the two-step process.

100 项与 Cosar Pharm Co. 相关的药物交易

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100 项与 Cosar Pharm Co. 相关的转化医学

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