Parastomal hernia (PH) remains a significant complication following stoma creation, boasting a considerable prevalence in the range of 30 to 50% within the first year post-surgery, a figure that climbs even higher when considering radiological evidence irrespective of clinical symptoms. A noteworthy one-third of these cases necessitate subsequent surgical interventions, yielding suboptimal outcomes both in the short and long term. The clinical manifestations of PH are diverse, ranging from mild inconveniences like fecal leakage and dermatitis to more severe and potentially life-threatening complications such as intestinal obstruction, hernia incarceration, and ischemia.
Various systematic reviews and meta-analyses have advocated for the adoption of prophylactic meshes, although defining precise incidence and recurrence rates has proven challenging due to methodological disparities across studies. Keyhole and modified Sugarbaker techniques dominate laparoscopic and robotic approaches, yet none offer ideal outcomes.
The aim of this study is to evaluate the decrease of postoperative parastomal hernia using this three-dimensional, funnel-shaped mesh.

开始日期2024-08-01

申办/合作机构

Consorci Sanitari Integral

NCT05948852 / Not yet recruitingN/A

Randomized Prospective Study Comparing Two Hypoabsorption Techniques for the Treatment of Type III Obesity (Body Mass Index Between 45 - 49.9 Kg/m2): Single Anastomose Duodenal Switch (SADI-S) and Single Anastomose Gastric By-pass (OAGBP)

This study aims to compare the percentage of total weight lost in long-term follow-up after two surgical interventions (SADIS and OAGB) in patients with morbid obesity BMI between 45-49.9.

开始日期2023-07-01

申办/合作机构

Consorci Sanitari Integral

NCT05815914 / RecruitingN/A

Dietetic Education Support, and Nutrition to Chronic Complex Patients With the Usage of a Telemedicine Tool

The aim of this clinical trial is to assess the implementation of an APP to track the nutritional status and diet habits of "chronic complex patients"(CCP) in order to improve their nutritional status and evaluate the level of adherence to dietetic counseling.

开始日期2022-04-01

申办/合作机构

Consorci Sanitari Integral

100 项与 Consorci Sanitari Integral 相关的临床结果

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0 项与 Consorci Sanitari Integral 相关的专利（医药）

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项与 Consorci Sanitari Integral 相关的文献（医药）

2018-01-01·Hysteroscopy

Endometrial Osseous Metaplasia

作者: Laura Acín ; Natalia Giraldo ; Enric Cayuela ; Estefania Llanos ; Federico Heredia ; Patricia Zarco ; Josep Vilanova ; María del Río

Bone metaplasia of the endometrium is an uncommon entity characterized by the presence of fragments of mature bone in the endometrium. Without presenting a defined syndrome, it is often associated with infertility, bleeding, and pain. The origin of this bone tissue has been interpreted as sequelae of early abortion, with no basis other than the statistical association between the two conditions. However, recent studies based on genetic identification techniques of DNA allow reinterpreting the phenomenon and establish that endometrial bone metaplasia originates from the patient’s stem cells lying in the endometrium. Diagnosis is based on ultrasound detection and subsequent confirmation by hysteroscopy, which usually shows excellent clinical results with more than 70% of cases of regaining fertility.

2016-01-01·Arthroscopy

Arthroscopy of Subtalar Joint

作者: Xavier Martin Oliva ; Juan Manuel Rios ; Matteo Guelfi

The talus is an irregularly shaped tarsal bone with three articular surfaces which serve for the articulation with the calcaneus. The subtalar joint acts as a hinge with beveled surfaces connecting the talus and the calcaneus. Between the articulation of the posterior and middle articular facets, we can find a deep groove, the sinus tarsi, which runs obliquely forward and lateralward. This structure is broader and deeper in front filled up in the fresh state by the interosseous talocalcaneal ligament.

2015-12-01·Journal of Clinical Psychopharmacology4区 · 医学

Additional Effect on Sleep and Motor Dysfunction

4区 · 医学

Article

作者: Leon, Lucia ; Caballol, Nuria ; Cardona, Xavier ; Bello, Juan ; Avila, Asuncion ; Martin-Baranera, Montserrat ; Millet, Pablo

Depression and sleep disorders are among the most prevalent nonmotor symptoms of Parkinson disease (PD). Because agomelatine acts as a MT1 and MT2 agonist and as a 5HT2c antagonist, this study was designed to assess the efficacy of agomelatine in treating depressive symptoms in PD patients, and the potential changes both in sleep quality and motor symptoms. Depressed patients with PD were treated with agomelatine for 6 months, and they were evaluated with an array of scales. Completed nocturnal video-polysomnography was performed at baseline and week 12. The efficacy analysis population included 24 patients (12 men). The mean (SD) age was 75.2 (8.3) years. The mean (SD) daily dose of agomelatine was 25.00 (10.43) mg at 24 weeks. No changes in dopamine replacement therapy were made. There was a significant decrease in the 17-item Hamilton Depression Scale score over the course of the study (P < 0.0005). The Scales for Outcomes in Parkinson disease Sleep Questionnaire showed a statistically significant improvement over time in each of its subscales: nighttime sleep (P < 0.005), last month nighttime sleep (P < 0.0005), and daytime sleepiness (P < 0.0005). Surprisingly, changes over time in the motor subscale of Unified Parkinson Disease Rating Scale were statistically significant (P < 0.0005). Periodic limb movements and awakenings measured by polysomnography improved significantly (P < 0.005 and P < 0.05, respectively). We concluded that the use of agomelatine in PD depressed patients may have a considerable therapeutic potential because of its dual action for treating both symptoms of depression and disturbed sleep given its secondary beneficial effects regarding the reduction of extrapyramidal symptoms.

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