Scutellarin in Dengzhan Huasu tablets was determined HPLC was used, column: DS-C18 mobile phase: methanol-tetrahydrofuran-0.3% phosphoric acid (12:13:75), wave length: 335 nm. The linear range was 10-100 μg/mL (r = 0.9999), recovery rate was 99.49%, RSD = 1.13%. The method is rapid, simple, and accurate.