更新于：2024-11-01

SN Medical College, Agra

更新于：2024-11-01

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项与 SN Medical College, Agra 相关的临床试验

NCT05040126 / Active, not recruiting临床3期IIT

Evaluate the Effectiveness, Safety and Tolerability of Various Doses of Linezolid in Combination With Bedaquiline and Pretomanid in Adults With Pre-Extensively Drug-Resistant (Pre-XDR), Or Treatment Intolerant/Non-responsive Multidrug-Resistant (MDRTI/NR) Pulmonary Tuberculosis in India

Existing problem with DR TB management:
Injectable regimens for longer duration with toxicity Poor adherence, treatment failures, continued transmission
Need of the study:
Oral regimens of shorter duration Improved treatment adherence Implementation of community-based models of care Reduction in direct costs and indirect costs of patients Improved treatment outcomes
Need for shorter, tolerable and effective regimen
Hence modified BPaL regimen is designed to study the newer shorter oral in varying doses of Linezolid for pre XDR Tb patients and MDR TI/NR patients

开始日期2021-10-07

申办/合作机构

SN Medical College, Agra

[+1]

CTRI/2020/12/029868 / Not yet recruitingN/AIIT

An observational Study to Asses mRNA expression levels of Blimp1 alpha and beta in SARSCoV-2 infected subjects

开始日期2020-12-23

申办/合作机构

SN Medical College, Agra

CTRI/2020/08/027038 / Not yet recruiting临床3期IIT

A Prospective ,randomized ,double blind,placebo controlled study to access effects of nano ozonized hydrogen peroxide nebulization on results of RTPCR for noval corona virus thus infectivity and clinical course among mild to moderate sick Covid 19 patients HOPE in Covid 19(Hydrogen Peroxide Inhalation).

开始日期2020-08-20

申办/合作机构

SN Medical College, Agra

100 项与 SN Medical College, Agra 相关的临床结果

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0 项与 SN Medical College, Agra 相关的专利（医药）

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项与 SN Medical College, Agra 相关的文献（医药）

2024-03-01·INTERNATIONAL JOURNAL OF SCIENTIFIC RESEARCH

UNRAVELING TAKAYASU ARTERITIS: INCIDENTAL DIAGNOSIS DURING EMERGENCY LAPAROTOMY FOR MESENTERIC VOLVULUS WITH ATYPICAL PRESENTATION

作者: Sharma, Mayank ; Aggarwal, Deepak

Takayasu's arteritis, known as "pulseless" disease, is a large-vessel inammatory vasculitis primarily affecting the aorta and its branches1. Its diverse manifestations pose diagnostic challenges. Our case involves a 56-year-old female presenting with acute abdomen leading to emergency laparotomy. Intraoperatively, suspicion arose of upper limb vascular abnormality due to discordant limb pulses, prompting postoperative CT aortogram revealing occlusion of the brachiocephalic trunk. This conrmed Takayasu's arteritis diagnosis. The case underscores the signicance of recognizing clinical discordance, early diagnosis, and the importance of a multidisciplinary approach.

2023-10-01·The Journal of Obstetrics and Gynecology of India

Sheehan’s Syndrome in India: Clinical Characteristics and Laboratory Evaluation

Article

作者: Agrawal, Mohita ; Singh, Manish Kumar ; Verma, Urvashi ; Chauhan, Richa ; Garg, Ruchika ; Agrawal, Prabhat

BackgroundSheehan's Syndrome (SS) is an important cause of hypopituitarism especially in developing countries though it remains underdiagnosed to a great extent. Torrential bleeding after delivery followed by lactation failure and amenorrhoea gives a clue to the diagnosis which is usually made after several years of delivery.Materials and MethodsIt was a retrospective observational study conducted by reviewing the case records of 38 cases of SS. The age, anthropometric measurements, signs and symptoms, biochemical parameters, hormone levels and imaging reports were examined and analyzed.ResultsThe mean age at presentation was 36.5 years because there was a delay of 8.4 years from last delivery before diagnosis could be made. Ninety percent patients presented with lactation failure. Anaemia, hypotension, hypogonadism, hypothyroidism, and altered lipid profile were the most common findings. The mean systolic blood pressure (BP) was 80.95 mm and diastolic BP was 51.6 mm of Hg at the time of presentation. Hyponatremia was the most common electrolyte abnormality noted and low HDL was the commonest lipid abnormality.ConclusionA large percentage of patients presented with amenorrhea, lactation failure, and decreased or absent axillary/pubic hair. Shock, anemia, and hyponatremia were also common symptoms among the patients studied. The diagnosis of SS rests upon a thorough history taking of the postpartum events in cases presenting with hypopituitarism irrespective of the age at presentation. Proper antenatal care with exclusive institutional deliveries can reduce the prevalence of SS in developing countries.

2023-03-01·Indian Journal of Surgical Oncology

Observational Study to Determine the Involvement of Level III Lymph Nodes in Case of Clinically Positive Level II Nodes in Carcinoma Breast

Article

作者: Dwivedi, Sabita ; Dwivedi, Surjeet ; Hans, Raj ; Shankaran, R ; Saidha, Naresh ; Chaudhary, Abhimanyu ; Arnav, Amiy ; Agarwal, Varun ; Sharma, Rohit ; Mukherjee, Debashish

Management of breast cancer has gradually shifted from era of radical surgery to present days of multimodality management and conservatism. Management of carcinoma breast is primarily multimodality of which surgery is one of the important roles to play. Our study is a prospective observational study to determine the involvement of level III axillary lymph nodes in clinically involved axilla with grossly involved lower-level axillary nodes. Underestimation of a number of involved nodes at level III shall result in inaccuracy of subset risk stratification leading to substandard prognostication. The enigma of not addressing presumably involved nodes thereby altering the staging vs acquired morbidity has always been a contentious issue. Mean lymph node harvest at the lower level (I and II) was 17.9 ± 6.3 (range: 6-32) while positive lower-level axillary lymph node involvement was 6.5 ± 6.5 (range: 1-27). The mean ± SD for level III positive lymph node involvement was 1.46 ± 1.69 (range: 0-8). Our prospective observational study though limited by the number and years of follow-up has demonstrated that the presence of more than three positive LN at a lower level increases the risk for higher nodal involvement substantially. It is also evident in our study that PNI, ECE, and LVI increased the probability of stage up-gradation. LVI was found to be a significant prognostic factor for apical LN involvement in multivariate analysis. On multivariate logistic regression > 3 pathological positive lymph nodes at the level I and II and LVI involvement elevated the risk of involvement at level III by 11 and 46 times, respectively. It is recommended that patients who have a positive pathological surrogate marker of aggressiveness should be evaluated perioperatively for level III involvement, especially in the setting of visible grossly involved nodes. The patient should be counseled and informed decision to perform complete axillary lymph node dissection with the added risk of morbidity should be contemplated.

100 项与 SN Medical College, Agra 相关的药物交易

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100 项与 SN Medical College, Agra 相关的转化医学

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