Vardhman Mahavir Medical College & Safdarjung Hospital (Vardhman Mahavir Medical College & Safdarjung Hospital)

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189

项与 Vardhman Mahavir Medical College & Safdarjung Hospital 相关的临床试验

CTRI/2024/09/074453 / Not yet recruiting临床3期IIT

Effect of Remote Ischemic conditioning on albuminuria in adults with Diabetes mellitus (RICADIME): A Parallel group, double blind, Sham controlled, Randomized clinical trial - RICADIME

开始日期2024-10-01

申办/合作机构

Vardhman Mahavir Medical College & Safdarjung Hospital

CTRI/2024/09/073379 / Not yet recruitingN/AIIT

Comparison of ultrasound guided erector spinae plane block and caudal block for postoperative analgesia in paediatric patients undergoing infraumbilical surgery - NIL

开始日期2024-10-01

申办/合作机构

Vardhman Mahavir Medical College & Safdarjung Hospital

CTRI/2024/08/072168 / Not yet recruitingN/AIIT

Comparison of Caval aorta index with Internal jugular vein collapsibility index to predict post spinal anaesthesia hypotension in controlled hypertensive patients - NIL

开始日期2024-09-05

申办/合作机构

Vardhman Mahavir Medical College & Safdarjung Hospital

100 项与 Vardhman Mahavir Medical College & Safdarjung Hospital 相关的临床结果

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0 项与 Vardhman Mahavir Medical College & Safdarjung Hospital 相关的专利（医药）

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2,670

项与 Vardhman Mahavir Medical College & Safdarjung Hospital 相关的文献（医药）

2024-10-01·Journal of Hand and Microsurgery

Hatchet flap for distal fingertip amputations

Article

作者: Tandon, Raman ; Tripathi, Komal ; Nemichand ; Reddy, Dharmala Nitesh

Purpose- Fingertip amputations are responsible for significant pain, suffering, discomfort as well as lost productivity and financial and physical hardship. Distal finger tip amputations pose a unique reconstructive challenge as the aim is to provide a supple cover with sensation. Wide variety of options are available for the reconstruction following fingertip amputations. This study evaluates the use of hatchet flap in the management of distal fingertip amputations.MethodsThe hatchet flap was done in 35 fingers of 31 patients with fingertip amputations at the level of distal phalanx who presented to our unit, fulfilling the inclusion criteria during a period of 18 months. All transverse and dorsal oblique amputations (of any size) at the level of distal phalanx of any age group were included in the study. Volar fingertip amputations at the level of distal phalanx and fingertip amputations associated with other injury over the volar aspect of finger were excluded from the study.ResultsThe flap provided a very good padded soft tissue cover with good aesthetic shape to the finger tip. The scars were unnoticeable with an average 2 point discrimination of 6.7 mm at 12 weeks post operatively. Paresthesia was noted maximally at 1 week post operative duration. Joint stiffness was not noted in any patient. Most patients were able to return back to their normal daily routine at around 3 weeks. Complete flap necrosis was noted in 1 patient while partial tip necrosis was noted in 2 patients.ConclusionThe hatchet flap serves as a good local reconstructive flap option which preserves the tactile sensation and is a valuable addition to the wide armamentarium of reconstructive procedures available for treating the distal fingertip amputations.

2024-10-01·Pathology - Research and Practice

Understanding the spectrum of HER2 status in breast cancer: From HER2-positive to ultra-low HER2

Review

作者: Zaheer, Sufian ; Ahuja, Sana ; Khan, Adil Aziz

2024-10-01·Cardiovascular Toxicology

Prevalence, Outcomes, and Predictors of Prolonged Corrected QT Interval in Hydroxychloroquine-Naïve Hospitalized COVID-19 Patients

Article

作者: Gupta, Kapil ; Gupta, Anunay ; Sharma, Monica ; Balakrishnan, Ira ; Bansal, Sandeep ; Gupta, Praveen

The studies regarding prevalence, outcomes, and predictors of prolonged corrected QT (QTc) among COVID-19 patients not on QTc-prolonging medication are not available in the literature. In this retrospective cohort study, the QTc of 295 hospital-admitted COVID-19 patients was analyzed and its association with in-hospital mortality was determined. The QTc was prolonged in 14.6% (43/295) of the study population. Prolonged QTc was seen in patients with older age (P = 0.018), coronary artery disease (P = 0.001), congestive heart failure (P = 0.042), elevated N-terminal-pro-B-type natriuretic peptide (NT-ProBNP) (P < 0.0001), and on remdesivir (P = 0.046). No episode of torsades de pointes arrhythmia or any arrhythmic death was observed among patients with prolonged QTc. The mortality was significantly high in patients with prolonged QTc (P = 0.003). The multivariate logistic regression analysis showed coronary artery disease (odds ratio (OR): 4.153, 95% CI 1.37-14.86; P = 0.013), and NT-ProBNP (ng/L) (OR: 1.000, 95% CI 1.000-1.000; P = 0.007) as predictors of prolonged QTc. The prolonged QTc was associated with the worst in-hospital survival (p by log-rank 0.001). A significant independent association was observed between prolonged QTc and in-hospital mortality in multivariate cox-regression analysis (adjusted hazard ratio: 3.861; (95% CI 1.719-6.523), P < 0.0001). QTc was found to be a marker of underlying comorbidities among COVID-19 patients. Prolonged QTc in hospitalized COVID-19 patients was independently associated with in-hospital mortality.

100 项与 Vardhman Mahavir Medical College & Safdarjung Hospital 相关的药物交易

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100 项与 Vardhman Mahavir Medical College & Safdarjung Hospital 相关的转化医学

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