Canadian Immunization Research Network

The goal of this pilot demonstration and evaluation project is to increase the accessibility and uptake of recommended immunizations in the general public by implementing a transitional stepped co-payment model in community pharmacies in Nova Scotia and Ontario for the delivery of recommended but unfunded vaccines until full public funding is available. The main question it aims to answer is:
* Can a transitional stepped co-payment model through pharmacies for the delivery of recommended but unfunded vaccines (e.g., Shingrix, FluMist) increase the accessibility and uptake of recommended immunizations among various stakeholders until full public funding is available?
Participants will:
* Receive a reduced cost of the vaccine (if eligible) through this transitional stepped co-payment funding model, as part of routine care (following standard pharmacy practice).
* Complete a feedback and satisfaction survey exploring their thoughts on the transitional stepped co-payment model, their satisfaction with the co-payment model, their perception on vaccinations in general and specifically about recommended but unfunded vaccines, and their demographics (such as gender, age, education, race/ethnicity).

The main goals of this study are to assess the immune response and safety of two different vaccines for first, second, third and fourth doses as well as for differing intervals between the first and second dose of two-dose vaccines.

This study evaluates whether priming influenza naive infants, age six to 23 months, with a MF59-adjuvanted (oil in water emulsion) influenza vaccine is preferred to priming with an inactivated unadjuvanted influenza vaccine. All participants will receive a priming vaccine, either MF59-adjuvanted trivalent influenza vaccine (aTIV) or unadjuvanted quadrivalent influenza vaccine (QIV). For the booster shot the following year, two thirds of participants will receive QIV and one third will receive MF59-adjuvanted vaccine.