More than half of the Dutch population is overweight or obese, which is associated with an increased risk of Covid-19 and worse outcomes during a Covid-19 infection. In addition, malnutrition and loss of muscle mass are often reported with Covid-19, as well as with cancer and other diseases. Malnutrition and overweight or obesity can coexist, even within the same individual. It is still unclear which mechanisms contribute to the worse outcomes of Covid-19 and other diseases in case of overweight, malnutrition, and a combination of both. We aim to identify which parameters are associated with worse disease outcomes through literature research and database research (Covid-19 and cancer, more than 150.000 participants). In addition, we will conduct a clinical study aiming to develop a simple screening tool for the recognition of the coexistence of malnutrition and overweight or obesity in clinical practice.

开始日期2024-10-02

申办/合作机构

HAN University of Applied Sciences

[+3]

NCT06282757 / Not yet recruitingN/AIIT

The Effect of Physiotherapists' Placebo or Nocebo Communication About Virtual Reality on Treatment Beliefs in Patients With CMP

Rationale: Chronic musculoskeletal pain (CMP) is a common and disabling condition. Physiotherapy is the most frequently administered non-pharmacological treatment option for patients with CMP and recently virtual reality (VR) was introduced in physiotherapy care as a novel treatment modality. Proper communication about physiotherapy treatment (modalities) is important to improve treatment outcomes, by applying placebo effects enhancing communication and avoiding nocebo effects enhancing communication. However, yet is still unknown to what extent this applies to communication of physiotherapists about VR in patients with CMP.
Objective: To determine the effect of physiotherapists' placebo or nocebo therapeutic communication about VR, on treatment credibility and expectation in patients with CMP
Study design: Web-based randomized controlled trial.
Study population: 100 participants
Intervention: The placebo intervention group will be shown an educational video about VR, containing placebo effects enhancing verbal language. The nocebo intervention group will be shown an educational video about VR, containing nocebo effects enhancing verbal language.
Primary study parameters: The primary study parameters are treatment credibility and treatment expectation. Treatment credibility and treatment expectations will be measured using the Dutch credibility and expectancy questionnaire (CEQ).

开始日期2024-04-01

申办/合作机构

HAN University of Applied Sciences

NL-OMON53210 / RecruitingN/AIIT

The effect of collagen supplementation on human tendon protein synthesis - Collagen for tendon remodelling

开始日期2024-03-01

申办/合作机构

HAN University of Applied Sciences

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1,449

项与 HAN University of Applied Sciences 相关的文献（医药）

2024-12-31·International Review of Sport and Exercise Psychology

Resilience in sports: a multidisciplinary, dynamic, and personalized perspective

Article

作者: Brink, Michel S. ; Atzmueller, Martin ; Platvoet, Sebastiaan ; Brauers, Jur J. ; Emerencia, Ando ; Meerhoff, L. Rens A. ; Hill, Yannick ; Van Yperen, Nico W. ; Frencken, Wouter G. P. ; Lemmink, Koen A. P. M. ; Neumann, Niklas D. ; Den Hartigh, Ruud. J. R.

Athletes are exposed to various psychological and physiological stressors, such as losing matches and high training loads. Understanding and improving the resilience of athletes is therefore crucial to prevent performance decrements and psychological or physical problems. In this review, resilience is conceptualized as a dynamic process of bouncing back to normal functioning following stressors. This process has been of wide interest in psychology, but also in the physiology and sports science literature (e.g. load and recovery). To improve our understanding of the process of resilience, we argue for a collaborative synthesis of knowledge from the domains of psychology, physiology, sports science, and data science. Accordingly, we propose a multidisciplinary, dynamic, and personalized research agenda on resilience. We explain how new technologies and data science applications are important future trends (1) to detect warning signals for resilience losses in (combinations of) psychological and physiological changes, and (2) to provide athletes and their coaches with personalized feedback about athletes' resilience.

2024-12-31·International Journal of Qualitative Studies on Health and Well-being

A qualitative study on the facilitators and barriers to adopting the N-of-1 trial methodology as part of clinical practice: potential versus implementation challenges

Article

作者: Wilmont, Ilona ; Loeffen, Mark ; Hoogeboom, Thomas

PURPOSETo investigate opinions among healthcare stakeholders whether implementation of the N-of-1 trial approach in clinical practice is a feasible way to optimize evidence-based treatment results for unique patients.METHODSWe interviewed clinicians, researchers, and a patient advocate (n = 13) with an interest in or experience with N-of-1 trials on the following topics: experience with N-of-1, measurement, validity and reliability, informally gathered data usability, and influence on physician-patient relationship. Interviews were analysed using qualitative, thematic analysis.RESULTSThe N-of-1 approach has the potential to shift the current healthcare system towards embracing personalized medicine. However, its application in clinical practice carries significant challenges in terms of logistics, time investment and acceptability. New skills will be required from patients and healthcare providers, which may alter the patient-physician relationship. The rise of consumer technology enabling self-measurement may leverage the uptake of N-of-1 approaches in clinical practice.CONCLUSIONSThere is a strong belief that the N-of-1 approach has the potential to play a prominent role in transitioning the current healthcare system towards embracing personalized medicine. However, there are many barriers deeply ingrained in our healthcare system that hamper the uptake of the N-of-1 approach, making it momentarily only interesting for research purposes.

2024-12-01·International Journal of Sports Science & Coaching

Multidimensional performance characteristics of talented youth judoka: Dynamic balance and coping skills relate to international competitive performance

作者: Schoof, Suzan ; Pion, Johan ; Lojanica, Maria B. ; Krabben, Kai ; Elferink-Gemser, Marije T.

Understanding of the multidimensional performance characteristics (MPCs) that underlie performance and distinguish athletes of varying performance levels are key for talent development programs. However, in the Olympic combat sport of judo, including MPCs in talent development research is still a recent approach. Hence, little is known about the MPCs of talented youth judoka. Therefore, this study aimed to determine differences in MPCs of talented youth (U18) judoka with varying levels of success in international competition, specified by sex and corrected for body weight. Fifty-two international level judoka (males: n = 28, age: 16.7 ± 0.9 and females: n = 24, age: 16.3 ± 0.9) participated. Multiple linear regressions were performed with performance level as the dependent variable. Performance level was defined as the win rate at international competitions in one competitive season. Anthropometrical (e.g., body height), physiological (e.g., dynamic balance), and psychological (e.g., coping skills) characteristics were used as independent variables. Results showed that win rate of females positively relates to dynamic balance and coping with adversity, and negatively relates to goal setting and mental preparation ( R2 = .611, p < .001). Peaking under pressure positively relates to the win rate of males ( R2 = .152, p < .05). The extent to which MPCs explain competition performance differs between sexes. However, for both sexes, coping skills seem to be important. Therefore, it is recommended that psychological characteristics are integrated in talent programs of youth judoka next to the judo-specific, physiological and/or technical-tactical trainings whilst taking in consideration the individual differences.

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