Tau protein, Neutrophil-to lymphocyte ratio, C-Reactive Protein to albumin as predictive tools for post-operative cognitive dysfunction in oncosurgical patients : In single centre study: a Prospective observational study. - nil

开始日期2024-08-15

申办/合作机构

Swami Rama Himalayan University

CTRI/2024/06/069102 / Not yet recruiting临床4期IIT

Evaluation and analysis of different laryngeal mask airway LMA Blockbuster, LMA Proseal and LMA Baska in terms of oropharyngeal leak pressure and post operative sore throat in patient undergoing elective laparoscopic cholecystectomy - nil

开始日期2024-06-25

申办/合作机构

Swami Rama Himalayan University

100 项与 Swami Rama Himalayan University 相关的临床结果

登录后查看更多信息

0 项与 Swami Rama Himalayan University 相关的专利（医药）

登录后查看更多信息

651

项与 Swami Rama Himalayan University 相关的文献（医药）

2024-11-01·Lupus

Early diagnosis of lupus: A possibilty. A multicentric study from SLE Special Interest Group (SIG) of Indian Rheumatology Association (IRA)

Article

作者: Aggarwal, Amita ; Selvam, Sumithra ; Shobha, Vineeta ; Nallasivan, Subramanian ; Jain, Avinash ; Rajasekhar, Liza ; Malviya, Sourabh ; Singh, Aradhana ; V, Shaleni ; Gupta, Ranjan ; Yadav, Deepak ; Preet Singh, Yogesh ; KR Rao, Vijay ; Ponniah Subramanian, Arul R ; Mathew, John

Introduction Systemic Lupus Erythematosus (SLE) warrants an early diagnosis and prompt management. Delay in diagnosis can result in repeated flares, permanent damage, and even death. There is a large variability in the time taken to diagnose SLE across the world. We undertook this study to determine the time taken for diagnosis of SLE in India and to identify the factors associated. Methods Patients with SLE diagnosed within the previous 1 year as per Systemic Lupus Erythematosus International Collaborating Clinics criteria (SLICC) 2012 criteria were included in a cross-sectional multicentre questionnaire-based survey. Demographic profile, self-reported socioeconomic status as per Kuppuswamy classification of socioeconomic status (version 2022) (SES), and several healthcare related parameters including referral pattern were recorded. Median time taken for diagnosis was used to demarcate early or late diagnosis and associated factors were explored. Results We included 488 patients with SLE from 10 rheumatology centres. The median time to diagnosis was 6 months Interquartile Range (IQR 3,14.7) and within 3 months in about one third [150(30.7%)]. Very early diagnosis (<1 month) was established in 78(16.0%) patients. The mean SLE Disease Activity Index (SLEDAI) at diagnosis was 10.28+7.24. In univariate analysis, an older age, lower SES, non-southern state of residence and larger family size were significantly associated with late diagnosis. In the multivariate analysis, higher SES (AOR 0.95, 95% CI: 0.92-0.98), multiple organ system involvement at initial presentation (AOR1.75 95%CI: 1.08–2.84) and place of residence in south Indian states (AOR1.92 95%CI: 1.24–2.97) had lesser odds of being associated with late diagnosis. Distance from the closest medical centre/professional did not influence the time to diagnosis. Majority of patients had first consulted a medical graduate (42.5%) or postgraduate doctor (48.2%), and referral to rheumatologist was largely done by postgraduate (65%) doctors. More than half of our patients (61%) self-finance their treatment. Conclusion Median time to diagnosis of SLE was 6 months, 1/3rd being diagnosed within 3 months and 78(16.0%) with 1 month of symptom onset. Delay in diagnosis was noted in those belonging to lower socioeconomic strata and those with single organ disease. Distance to the health care facility did not influence time to diagnosis.

2024-11-01·Transfusion Clinique et Biologique

Beyond the Microscope: A memoir of Professor Sudha S. Bhat, an iconic Indian pathologist, and a transfusion medicine specialist

Article

作者: Shivhare, Aditya ; Shastry, Shamee ; Raturi, Manish

2024-10-01·Food Chemistry

Encapsulation of debittered pomelo juice using novel Moringa oleifera exudate for enrichment of yoghurt: A techno-functional approach

Article

作者: Jha, Avinash Kumar ; Naik, Bindu ; Das, Tanuva ; Rustagi, Sarvesh ; Gupta, Arun Kumar ; Kumar, Vijay ; Khan, Javed Masood

Debittering of pomelo juice was conducted using 3.7 g of activated resin, resulting in a 36.8% reduction in bitterness without affecting the bioactive properties of juice. The debittered juice was then encapsulated with Moringa oleifera exudate at various ratios (1-5%), yielding a powder with a slightly rough surface. Total phenol content (TPC) increased by 46-56% compared to the debittered juice. Functional yoghurt containing encapsulates at concentrations of 1% and 2% demonstrated that the 2% concentration led to longer storage duration, resulting in increased acidity and syneresis compared to the control. TPC of the yoghurt (161.89-198.22 μg Gallic acid equivalent (GAE)/g) remained significantly higher (p < 0.05) than that of the control (47.15 μg GAE/g) and acacia gum-based yoghurt (141.89-171.37 μg GAE/g), decreasing with storage duration. Addition of encapsulates significantly altered the yoghurt's texture, resulting in lower firmness (0.57 to 0.64 N) compared to the control, while adhesiveness values remained comparable (6.33 to 6.25 g.s). The highest values of G' and G" were observed in samples containing 2% encapsulates with moringa compared to those with acacia gum. This study suggests potential avenues for further exploration in functional foods with enhanced health benefits.

100 项与 Swami Rama Himalayan University 相关的药物交易

登录后查看更多信息

100 项与 Swami Rama Himalayan University 相关的转化医学

登录后查看更多信息