Formula is the preferred alternative food for infants and young children when the supply of breast milk is insufficient. Although the compositions of other animal milk, such as bovine, were quite different from human milk, which had always been imitated by formula with the development of the research on the nutrition of breast milk. IgA (IgA), lysozyme and lactoperoxidase are important bioactive proteins in breast milk, which provide the immune effect for health of infants and young children. The study evaluated the concentrations of the above three active proteins in 12 com. young children formulas, including that the level range of IgA was 182.50∼436.94 mg/100 g, of lysozyme was 3.75∼7.15 mg/100 g, and of lactoperoxidase was 11.70∼49.96 mg/100 g, which shown different results in each sample. Then the relationship between protein content, source of raw milk and processing technol. was further analyzed. It was found that the levels of IgA and lactoperoxidase in domestic milk source were higher than those in imported ones, while the concentration of lysozyme might be related to the processing technol. In addition, Pearson correlation anal. was carried out and showed that IgA concentration was neg. correlated with lactoperoxidase (r=-0.594, P<0.05), which still needs further study.