Delving into the Latest Updates on Accupharma Sp Zoo with Synapse

概览

排名前五的药物类型	数量

小分子化药	1

排名前五的靶点	数量

ACE x NKCC2	1

关联

1

项与 Accupharma Sp Zoo 相关的药物

Lisinopril/Torasemide

赖诺普利/托拉塞米

靶点

ACE x NKCC2

作用机制

ACE抑制剂 [+2]

在研机构

Accupharma Sp Zoo

原研机构

Accupharma Sp Zoo

在研适应症

原发性高血压 [+1]

非在研适应症-

最高研发阶段批准上市

首次获批国家/地区

波兰

首次获批日期2017-09-28

100 项与 Accupharma Sp Zoo 相关的临床结果

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0 项与 Accupharma Sp Zoo 相关的专利（医药）

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1

项与 Accupharma Sp Zoo 相关的文献（医药）

2017-11-01·Journal of AOAC INTERNATIONAL4区 · 农林科学

Characterization of Low-Molecular-Weight Heparins by Strong Anion-Exchange Chromatography

4区 · 农林科学

Article

作者: Widomski, Paweł ; Buszewski, Bogusław ; Gadzała-Kopciuch, Renata ; Sadowski, Radosław ; Jujeczka, Ludwik ; Kowalkowski, Tomasz

AbstractCurrently, detailed structural characterization of low-molecular-weight heparin (LMWH) products is an analytical subject of great interest. In this work, we carried out a comprehensive structural analysis of LMWHs and applied a modified pharmacopeial method, as well as methods developed by other researchers, to the analysis of novel biosimilar LMWH products; and, for the first time, compared the qualitative and quantitative composition of commercially available drugs (enoxaparin, nadroparin, and dalteparin). For this purpose, we used strong anion-exchange (SAX) chromatography with spectrophotometric detection because this method is more helpful, easier, and faster than other separation techniques for the detailed disaccharide analysis of new LMWH drugs. In addition, we subjected the obtained results to statistical analysis (factor analysis, t-test, and Newman–Keuls post hoc test).

100 项与 Accupharma Sp Zoo 相关的药物交易

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100 项与 Accupharma Sp Zoo 相关的转化医学

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