Evaluation of the Discomfort Contrast Induced during Angiographic evaluation of peripheral arterial occlusive disease to define the treatment approach for percutaneous transluminal balloon angioplasty (PTA). Randomized prospective trial, comparing two iodinated contrast media.

开始日期2012-04-10

申办/合作机构

Casa di Cura Abano Terme Polispecialistica e Termale SpA

EUCTR2010-022032-37-IT / Not yet recruitingN/A

Randomized, open-label, single centre study on ovarian stimulation in ART poor responders treated with recombinant FSH in association with recombinant LH.

开始日期2011-03-18

申办/合作机构

Casa di Cura Abano Terme Polispecialistica e Termale SpA

100 项与 Casa di Cura Abano Terme Polispecialistica e Termale SpA 相关的临床结果

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0 项与 Casa di Cura Abano Terme Polispecialistica e Termale SpA 相关的专利（医药）

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156

项与 Casa di Cura Abano Terme Polispecialistica e Termale SpA 相关的文献（医药）

2024-04-01·Reproductive BioMedicine Online

Comparison of clinical and ultrasound examinations in assessing the parametria in patients with deep infiltrating endometriosis: a multicentre prospective study

Article

作者: Fanfani, Francesco ; Biasioli, Anna ; Ianieri, Manuel Maria ; Virgilio, Bruna Anna ; Mascilini, Floriana ; Scaglione, Giulia ; Arcieri, Martina ; Scambia, Giovanni ; Lo Turco, Alice ; Beneduce, Giuliana ; Carlea, Annunziata ; Carfagna, Pietro ; Pontrelli, Giovanni ; Testa, Antonia Carla ; Ladisa, Irene ; Moro, Francesca ; De Cicco Nardone, Alessandra ; Vizzielli, Giuseppe

RESEARCH QUESTIONHow do clinical rectovaginal examination and transvaginal ultrasound examination perform in the diagnosis of parametrial infiltration in patients with endometriosis?DESIGNThis was a multicentre prospective observational study. Patients with suspected deep endometriosis at clinical examination and/or at ultrasound evaluation and scheduled for surgery were included. Following multicentre multidisciplinary meetings, consensus was obtained on terms and methodology to define the parametrium at pelvic anatomy, ultrasound and surgery. Sensitivity, specificity, accuracy, and positive and negative likelihood ratios were calculated for clinical and ultrasound examinations with respect to surgery.RESULTSIn total, 195 women were selected for the present study and 164 were included in the analysis. Ultrasound examination had good to high specificity (>80%) for all parameters, except the left lateral parametrium (78.8%). The sensitivity of ultrasound examination was good to high for fixity of the right and left ovaries, uterosacral ligaments, retrocervix and rectovaginal space; and low for the anterior and lateral parametria, vagina, bladder and bowel. Clinical examination had good to high specificity for fixity of the left ovary, anterior parametrium, right uterosacral ligament, retrocervix and vagina; and low specificity for fixity of the right ovary, lateral parametrium, left uterosacral ligament and rectovaginal space. The sensitivity of clinical examination was good for the uterosacral ligaments and rectovaginal space, and low for the remaining parameters.CONCLUSIONUltrasound examination provided good specificity for all the parameters, but sensitivity was low for the anterior and lateral parametria. Clinical examination provided good specificity for the anterior and posterior parametria, but sensitivity was low for the anterior and lateral parametria. Further prospective studies are needed to validate this methodology and confirm the results.

2024-03-06·The Journal of Maternal-Fetal & Neonatal Medicine4区 · 医学

Calcium and lactate in the fetal-to-neonatal transition

4区 · 医学

Article

作者: Straface, Gianluca ; Crivellaro, Carlo ; Severino, Lorenzo ; Zanardo, Vincenzo ; Sandri, Andrea ; Garani, Gianpaolo ; Simbi, Alphonse

OBJECTIVETo explore the relationship between calcium and lactate in arterial cord blood of healthy term neonates in response to the stress of labor.METHODSThis was a prospective cohort study of consecutive, vaginal, term births in a community medical center (April 2029 to February 2020). Calcium and lactate were measured in cord blood gas analysis immediately after delivery.RESULTSIn the arterial cord blood of 480 neonates, calcium levels were 1.5 (1.4; 1.5) mmol/L and lactate levels were 3.8 (2.9; 4.9) mmol/L. Calcium and lactate showed a statistically significant positive correlation (Pearson's correlation, r = 0.15, p = .001). Calcium levels had a significant positive correlation with PaCO₂ and a significant negative correlation with pH, PaO₂, HCO₃^-, and ABE levels. Multivariable analysis models confirmed that calcium levels were associated with HCO₃^-, gestational age, and birth weight, all accounting for 7% of the variability.CONCLUSIONIn healthy term vaginally delivered neonates, it was found that calcium and lactate were strongly correlated, together pointing to a neonatal response to the stress of labor and delivery. Cord blood calcium regulation may have an ancillary role in defining neonatal adaptation to extrauterine life.

2024-03-06·The Journal of Maternal-Fetal & Neonatal Medicine4区 · 医学

Postpartum bonding: the impact of stressful life events during pregnancy

4区 · 医学

Article

作者: Manghina, Valeria ; Tedde, Federica ; Callegher, Claudio Zandonella ; Sandri, Andrea ; Giliberti, Lara ; Strafaceee, Gianluca ; Zanardo, Vincenzo

OBJECTIVEWe aimed to determine if and to what extent a woman's exposure to stressful life events were associated with impaired maternal bonding by using a sample of high-income Italian women.METHODSIn the second day postpartum, 425 healthy puerperae responded to Life Experiences Survey (LES), Mother-to-Infant Bonding Scale (MBS), and to the Edinburgh Postnatal Depression Scale (EPDS).RESULTSAnalysis revealed that the stressful life events scored by LES were a significantly predictor of impaired bonding as measured by MIBS (β = 0.04; t = 3.45; p < .001) and of postpartum depression symptoms as measured by EPDS total score (β = 0.32; t = 4.86; p < .001) as well as its subscales Anhedonia (β = 0.059; t = 4.99; p < .001), Anxiety (β = 0.03; t = 5.72; p < .001), and Depression (β = 0.05; t = 6.53; p < .001). Moreover, the partial correlation between EPDS total score and MIBS accounting for LES positive and negative scores was statistically significant (r = 0.208; n = 332; p < .001).CONCLUSIONThe findings emphasize the importance of identifying mothers with negative experiences toward pregnancy and delivery to address possible interventions beyond hospital-based antenatal care to improve bonding and maternal mental outcomes.

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100 项与 Casa di Cura Abano Terme Polispecialistica e Termale SpA 相关的转化医学

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