A review.Trifluoromethylated building blocks are the subject matter of considerable interest in several successful industrial sectors including pharmaceuticals, agrochems., dyes, liquid crystals, electronic industries, polymers, etc.For example, fluorinated arenes are widely used as precursors for the synthesis of agrochems. and pharmaceuticals with a volume of several thousand tons per yr.More than 20% of the total newly developed pharmaceuticals, currently under clin. trials and about 50% of certain specialized newly developed agrochems. contain fluorinated aromatic substrates.This article provides a brief introduction of importance of trifluoromethylation technol. including available synthetic methodol., limitations, and applications.