The goal of this clinical trial is to evaluate an investigational ultralow dose PET imaging technique for prostate cancer detection and monitoring. The main question it aims to answer is:
Can the investigators optimize the timing, scan duration, and image reconstruction to reduce the radiation dose 10-100 fold of the current clinical standard?
Participants will be injected with a radioactive tracer called 18F-DCFPyL and be imaged on a new type of high sensitivity PET scanner for up to 3 hours

开始日期2025-05-01

申办/合作机构

Nuclear Energy Institute

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2022-03-16·Kerntechnik

A mathematic model of two-phase flow taking account of sub-cooled boiling, condensation, and void flashing

作者: Jiang, S. Y. ; Yang, X. ; Zhang, Y.

AbstractBased on a physical model of the test loop HRTL-5 simulating the 5 MW nuclear heating reactor, a drift-flux model of two-phase flow has been derived, in which the sub-cooled boiling and saturated boiling in the heated section, condensation and void flashing in the adiabatic riser etc, are taken into account. It is suitable to investigate the natural circulation two-phase flow, especially at heating reactor conditions. By introducing the concept of condensation boundary layer, a condensation formula has been derived and complemented into the drift-flux model, which was used to investigate the behavior of the HRTL-5 in our previous research works. Based on the mathematical model, a computer program has been developed. At first, through comparing the calculations with the experimental results, the parameters in the two-phase drift-flux model have been determined. Then calculations on the flow characteristics of HRTL-5 have been performed, including the simulation of the mass flow rate and the distribution of various physical variables. At last, the characteristic curves of natural circulation have been simulated; thereby, also useful experiences have been acquired.

2020-09-01

Flexible Nuclear Energy for Clean Energy Systems

作者: Moore, Megan ; Burton, Gordon ; Sim, Ki ; Marco, Bradley ; Siddiqui, Ali ; Frick, Konor ; Araj, Kamal ; Stone, Tim ; Arai, Shiro ; Kilic, Ness ; Throne, David ; Rising, Agneta ; Cox, Jordan ; Herzog, Antoine ; Wanner, Brent ; Gorman, John ; Chesire, Edwin ; Rogers, Philip ; Alexeeva, Victoria ; Shibata, Taiju ; Berthelemy, Michel ; Korsnick, Maria ; Hughes, Caroline ; Paillere, Henri ; Heek, Aliki ; Omoto, Akira ; Hill, Clement ; Bilbao-Y-Leon, Sama ; Peel, Gareth ; Forsberg, Charles ; Kamide, Hideki ; Fraser, Peter ; Feutry, Stéphane ; Monti, Stefano ; Nagasawa, Takeshi ; Brown, Maxwell ; Bragg-Sitton, Shannon ; Pavarini, Claudia

2020-02-01·Optics and Spectroscopy

The Mechanism of Formation of Nanostructures of Hexagonal Symmetry on Surfaces of Metals by a Sequence of Doubled Ultrashort Pulses of Radiation of Orthogonal Polarization

作者: V. S. Makin ; Yu. I. Pestov ; R. S. Makin

Abstract: Recent exptl. results on formation of ordered surface nanostructures of hexagonal symmetry on metals under the action of a series of scanned doubled collinear femtosecond pulses of orthogonal polarization and variable time delay are analyzed.It is demonstrated that the appearance of structures is related to the formation of a dynamic grating by the first pulse and excitation of two pairs of surface plasmon-polaritons by the second pulse in directions sym. with respect to its vector of polarization and forming an angle of π/3 with each other.This leads to the formation of corresponding dynamic gratings and fourfold degeneracy of the first grating.Three dynamic gratings sym. with respect to the surface normal form a residual surface relief of hexagonal symmetry that can be observed exptl.

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