aim of this study is to compare the effect of selective truncal blocks, performed at different doses and volumes, on the onset times of motor and sensory blocks required for anesthesia in patients scheduled for hand, wrist, forearm, and elbow surgeries. Completing the operation under regional anesthesia will be considered a successful block.

开始日期2024-11-01

申办/合作机构

Gaziosmanpasa Research and Education Hospital

NCT06664177 / Not yet recruitingN/AIIT

Comparison of the Postoperative Analgesic Efficacy of Quadratus Lumborum Block and Transversalis Fascia Block in Laparoscopic Inguinal Hernia Surgery

It is planned to compare the postoperative analgesic efficacy of the Transversalis Fascia Plane Block and the anterior Quadratus Lumborum Block in elective laparoscopic inguinal hernia surgeries.

开始日期2024-11-01

申办/合作机构

Gaziosmanpasa Research and Education Hospital

100 项与 Gaziosmanpasa Research and Education Hospital 相关的临床结果

登录后查看更多信息

0 项与 Gaziosmanpasa Research and Education Hospital 相关的专利（医药）

登录后查看更多信息

项与 Gaziosmanpasa Research and Education Hospital 相关的文献（医药）

2024-09-01·International Journal of Impotence Research

The prevalence and topographic distribution of penile calcification in a large cohort: a retrospective cross-sectional study

Article

作者: Bayraktarli, Recep Yilmaz ; Tuncer, Murat ; Otunctemur, Alper ; Alkan, Aykut ; Yazar, Selim ; Oktem, Cagri ; Yoldas, Mehmet ; Baran, Caner ; Akalin, Mustafa Kaan ; Kirdag, Mustafa Koray ; Kacan, Turgay ; Akgul, Burak ; Bulut, Berk ; Ergun, Kasim Emre ; Gonultas, Serkan ; Aydin, Mustafa ; Guzelburc, Vahit ; Bayraktar, Arif Bedirhan ; Guzel, Ahmet ; Gezmis, Cem Tugrul ; Kadioglu, Ates ; Cek, Hakki Mete ; Balci, Mustafa Bahadir Can ; Calik, Gokhan ; Ozgur, Berat Cem ; Efiloglu, Ozgur ; Durak, Huseyin Mert ; Ogras, Mehmet Sezai ; Kaya, Coskun ; Dogan, Kazim ; Demirelli, Erhan ; Aglamis, Erdogan ; Danacioglu, Yavuz Onur ; Culha, Mehmet Gokhan ; Can, Murat ; Aydin, Mehmet Erhan ; Cakan, Murat ; Yildirim, Asif

The prevalence of penile calcification in the population remains uncertain. This retrospective multicenter study aimed to determine the prevalence and characteristics of penile calcification in a large cohort of male patients undergoing non-contrast pelvic tomography. A total of 14 545 scans obtained from 19 participating centers between 2016 and 2022 were retrospectively analyzed within a 3-months period. Eligible scans (n = 12 709) were included in the analysis. Patient age, penile imaging status, presence of calcified plaque, and plaque measurements were recorded. Statistical analysis was performed to assess the relationships between calcified plaque, patient age, plaque characteristics, and plaque location. Among the analyzed scans, 767 (6.04%) patients were found to have at least one calcified plaque. Patients with calcified plaque had a significantly higher median age (64 years (IQR 56-72)) compared to those with normal penile evaluation (49 years (IQR 36-60) (p < 0.001). Of the patients with calcified plaque, 46.4% had only one plaque, while 53.6% had multiple plaques. There was a positive correlation between age and the number of plaques (r = 0.31, p < 0.001). The average dimensions of the calcified plaques were as follows: width: 3.9 ± 5 mm, length: 5.3 ± 5.2 mm, height: 3.5 ± 3.2 mm, with an average plaque area of 29 ± 165 mm² and mean plaque volume of 269 ± 3187 mm³. Plaques were predominantly located in the proximal and mid-penile regions (44.1% and 40.5%, respectively), with 77.7% located on the dorsal side of the penis. The hardness level of plaques, assessed by Hounsfield units, median of 362 (IQR 250-487) (range: 100-1400). Patients with multiple plaques had significantly higher Hounsfield unit values compared to those with a single plaque (p = 0.003). Our study revealed that patients with calcified plaques are older and have multiple plaques predominantly located on the dorsal and proximal side of the penis.

2024-09-01·Academic Radiology

Differentiation of Malignancy and Idiopathic Granulomatous Mastitis Presenting as Non-mass Lesions on MRI: Radiological, Clinical, Radiomics, and Clinical-Radiomics Models

Article

作者: Deger, Enes ; Kurt, Seda Aladag ; Ucar, Nese ; Saracoglu, Mehmet Sakıpcan ; Boy, Fatma Nur Soylu ; Icten, Gul Esen ; Kayadibi, Yasemin

RATIONALE AND OBJECTIVESTo investigate the effectiveness of machine learning-based clinical, radiomics, and combined models in differentiating idiopathic granulomatous mastitis (IGM) from malignancy, both presenting as non-mass enhancement (NME) lesions on magnetic resonance imaging (MRI), and to compare these models with radiological evaluation.MATERIAL AND METHODSA total of 178 patients (69 IGM and 109 breast cancer patients) with NME on breast MRI evaluated between March 2018 and April 2022, were included in this two-center study. Age, skin changes, presence of fistula, and abscess were recorded from hospital records. Two experienced radiologists evaluated MRI images according to the breast imaging reporting and data system 2013 lexicon. Lesions were segmented independently on T2-weighted, apparent diffusion coefficient, and post-contrast-T1-weighted sequences. Data were split into training and external testing sets. Machine learning models were built using Light GBM (light gradient-boosting machine). Radiological, clinical, radiomics, and clinical-radiomics models were created and compared. Decision curve analysis was performed. Quality of reporting and that of methodology were evaluated using CLEAR and METRICS tools.RESULTSIGM group was younger (p = 0.014). Abscesses (p < 0.001), fistulas (p < 0.001), and skin changes (p < 0.001) were significantly more common in the IGM group. No significant difference was detected in terms of lesion size (p = 0.213). In the evaluation of NME, the lowest performance belonged to the radiologists' evaluation (AUC for training, 0.740; for testing, 0.737), while the highest AUC was achieved by the model developed by combined clinical and radiomics features (AUC for training, 0.979; for testing, 0.942).CONCLUSIONOur study has shown that the machine learning-based clinical-radiomics model might have the potential to accurately discriminate IGM and malignant lesions in evaluating NME areas.

2024-05-01·Pancreatology

Acute pancreatitis in Turkey: Results of a nationwide multicenter study

Article

作者: Sezgin, Orhan ; Gül, Özlem ; Oruç, Nevin ; Altıntaş, Engin ; Bilgiç, Yılmaz ; Şair, Ümit ; Yurci, Alper ; Cindoruk, Mehmet ; Kalkan, İsmail Hakkı ; İrak, Kader ; Toka, Bilal ; Saruç, Murat ; Eminler, Ahmet Tarık ; Tahtacı, Mustafa ; Parlak, Erkan ; Yaraş, Serkan ; Barutçu, Sezgin ; Gökden, Yasemin ; Büyüktorun, İlker ; Koç, Deniz Öğütmen ; Şen, İlker ; Kösem, Gizem ; Yıldırım, Abdullah Emre ; Hakim, Gözde Derviş ; Oğuz, Dilek ; Soytürk, Müjde ; Köksal, Aydın Şeref ; Tozlu, Mukaddes ; Basır, Hakan ; Sağlam, Osman ; Ünal, Hakan ; Bengi, Göksel ; Ünal, Nalan Gülşen ; Özşeker, Burak ; Kasap, Elmas ; Özel, Mustafa ; Ergül, Bilal ; Nedirli, Ferda

BACKGROUNDAcute pancreatitis (AP) is the most common gastrointestinal disease requiring hospitalization, with significant mortality and morbidity. We aimed to evaluate the clinical characteristics of AP and physicians' compliance with international guidelines during its management.METHODSAll patients with AP who were hospitalized at 17 tertiary centers in Turkey between April and October 2022 were evaluated in a prospective cohort study. Patients with insufficient data, COVID-19 and those aged below 18 years were excluded. The definitions were based on the 2012 revised Atlanta criteria.RESULTSThe study included 2144 patients (median age:58, 52 % female). The most common etiologies were biliary (n = 1438, 67.1 %), idiopathic (n = 259, 12 %), hypertriglyceridemia (n = 128, 6 %) and alcohol (n = 90, 4.2 %). Disease severity was mild in 1567 (73.1 %), moderate in 521 (24.3 %), and severe in 58 (2.6 %) patients. Morphology was necrotizing in 4.7 % of the patients. The overall mortality rate was 1.6 %. PASS and BISAP had the highest accuracy in predicting severe pancreatitis on admission (AUC:0.85 and 0.81, respectively). CT was performed in 61 % of the patients, with the majority (90 %) being within 72 h after admission. Prophylactic NSAIDs were not administered in 44 % of the patients with post-ERCP pancreatitis (n = 86). Antibiotics were administered to 53.7 % of the patients, and 38 % of those received them prophylactically.CONCLUSIONSThis prospective study provides an extensive report on clinical characteristics, management and outcomes of AP in real-world practice. Mortality remains high in severe cases and physicians' adherence to guidelines during management of the disease needs improvement in some aspects.

100 项与 Gaziosmanpasa Research and Education Hospital 相关的药物交易

登录后查看更多信息

100 项与 Gaziosmanpasa Research and Education Hospital 相关的转化医学

登录后查看更多信息