Micromet AG

CAMBRIDGE, Mass., Feb. 1, 2024 /PRNewswire/ -- Myeloid Therapeutics, Inc. ("Myeloid"), a clinical stage oncology company, has appointed Robert Hofmeister, Ph.D., as Chief Scientific Officer (CSO). An expert in immuno-oncology, gene and cell therapy, Dr. Hofmeister brings more than 25 years of scientific leadership experience and a track record of drug discovery and early development. "As Myeloid advances our novel pipeline of programs, I am thrilled to welcome Dr. Hofmeister as our new Chief Scientific Officer. His successful track record leading drug discovery teams, which contributed to the approval of two drugs by the FDA, will be instrumental in building upon our achievements and navigating the promising opportunities ahead," said Daniel Getts, Ph.D., Myeloid CEO. Dr. Hofmeister's appointment comes at a crucial time when Myeloid has achieved numerous milestones, including a Phase 1 clinical study with MT-302 for patients with TROP2-expressing tumors. Notably, this study investigates the first in vivo mRNA CAR candidate to ever be dosed in patients. In the year ahead, the company is on track to advance its second in vivo CAR program to the clinic targeting GPC3-positive liver cancers. In addition to being a key member of the executive management team, Dr. Hofmeister will lead the expansion of Myeloid's cutting-edge RNA focused research and development efforts, aimed at designing novel therapeutics that target, deliver, and program immune cells to combat cancer and other deadly diseases. "I'm thrilled to work with Myeloid's world class team and cutting-edge in vivo engineering platform to revolutionize the treatment of cancer and autoimmune diseases, and make a difference in the lives of patients," Robert Hofmeister, Ph.D. "Myeloid's in vivo mRNA programming platform is positioned to dramatically change the future of cancer immunotherapy and the treatment of other devastating diseases." Before joining Myeloid, Dr. Hofmeister was the CSO at Resonance Medicine where he drove the development of their discovery platform for therapeutic proteases. Previously, he served as CSO at TCR2 Therapeutics where he started as employee number one and was instrumental in building and leading the R&D function, driving the development of their proprietary TRuC®-T cell platform from concept to first cleared IND (TC-210 program) and successfully contributed to taking the company public as well as securing multi-million dollar rounds of fundraising. Dr. Hofmeister also held various roles at EMD Serono where he was involved in the development of now approved Bavencio (avelumab) and building the company's immuno-oncology platform. He started his biotech career at Micromet AG, now Amgen Research Munich, where he helped shape the development of Blincyto (blinatumomab), the first FDA-approved bispecific antibody for the treatment of refractory ALL. Dr. Hofmeister received his Ph.D. from the University of Regensburg in Germany, where he studied the signaling of the cytokine interleukin-1. He continued to work in the cytokine field as a postdoctoral fellow at the National Cancer Institute. About Myeloid Therapeutics Myeloid Therapeutics is a clinical stage oncology company developing novel therapies for cancer. Integrating the fields of mRNA-based therapeutics, immunology, and cancer biology, the Company's proprietary platform provides clinical solutions for patients with solid tumors. Myeloid is headquartered in Cambridge, MA. For more information visit: . Media Contact: Jennifer Hanley Ridge Hill Group [email protected] Investor Contact Amy Conrad Juniper Point [email protected] SOURCE Myeloid Therapeutics, Inc.

- Dr Zbigniew Zasłona, PhD promoted to Chief Scientific Officer – Dr Zasłona remains a member of Molecure's Management Board - Dr Adam Gołębiowski transitioning from management board position to take on role of Senior Research Fellow WARSAW, Poland, Jan. 3, 2023 /PRNewswire/ -- Molecure S.A. ("Molecure": WSE: MOC) a clinical stage biotechnology company using its world leading medicinal chemistry capabilities to discover first-in-class small molecule drug candidates that directly modulate unexplored protein and RNA targets to treat multiple incurable diseases, announces that Dr. Samson Fung, Chief Medical officer has been appointed to the Company's management board. Dr. Adam Gołębiowski has stepped down from the management board to take on the role of Senior Research Fellow at Molecure. In parallel, Dr. Zbigniew Zasłona, has been promoted to Chief Scientific Officer from his current position as VP Research Biology. Dr. Zasłona, will remain on Molecure's management board. These changes are designed to better position the company to rapidly progress its clinical stage assets towards meaningful endpoints and partnering transactions, while simultaneously developing its early stage programs, including its innovative RNA discovery platform, to create a balanced pipeline of first-in-class assets with breakthrough therapy potential. Marcin Szumowski, Co-founder & CEO commented, "The new roles among our leadership team are tailored to support the successful development of our exciting clinical portfolio, which comprises 0ATD-01, which is targeting inflammatory lung diseases, starting with sarcoidosis, and OATD-02, which is being developed to treat a broad range of cancers. I would like to congratulate Samson as he becomes a new member of the management board where his significant pharmaceutical and biotech industry experience will be an important asset. I am also delighted to announce the promotion of Zbigniew to Chief Scientific Officer, which reflects the significant contribution he has made since joining Molecure. Dr. Adam Gołębiowski has initiated the discovery of both of our clinical stage assets enabling Molecure to become a clinical stage company. He has been instrumental in launching our early stage pipeline since co-founding Molecure and we look forward to having his continued engagement in a more science focused role in Molecure's early-stage programs. The experience within the senior leadership team combines deep scientific knowledge and clinical development expertise that will be important in helping us advance and broaden our pipeline." Dr Samson Fung graduated from the University of Freiburg, Germany and obtained his board certification in internal medicine with sub-specialization in oncology and hematology. Dr. Fung brings more than three decades of global industry and senior leadership experience across the life science sector. He has significant biotech experience with senior leadership roles (Head of Clinical Development, interim CMO) at several of Europe's most successful biotech companies including Micromet, later acquired by AMGEN, Morphosys and Argenx. Before that Dr Fung has held senior roles in clinical development, medical affairs, business development and strategic marketing at leading global pharmaceutical companies including Roche, Novartis, Pharmacia/Pfizer, Novo Nordisk and AstraZeneca. Dr Zbigniew Zasłona has been with Molecure for 2.5 years. He obtained his PhD in 2010 at the University of Giessen and the Marburg Lung Center in Germany, followed by a postdoctoral fellowship at the University of Michigan, USA. From 2015 to October 2020, he was a research fellow at Trinity College Dublin (Ireland) in the Department of Biochemistry and Immunology, as well as a Senior Investigator at the UK biotechnology company Sitryx (which in March 2020 entered into a $1bln collaboration and license agreement with Eli Lilly), where he was responsible for anti-inflammatory drug development programs. Dr. Zasłona has a publishing track record with h-index 26 and over 3000 citations. He is a recognized international expert in the field of inflammatory processes and lung diseases being repeatedly invited to lecture at leading international scientific conferences. Dr Adam Gołębiowski, who is a co-founder of Molecure has over 30 years of experience in leading research and development and drug discovery programs. In 1987 he completed his doctorate at the Institute of Organic Chemistry of the Polish Academy of Sciences, followed by a postdoctoral fellowship at Wayne State University, Michigan, USA. From 1989 to 2006, he led teams of medicinal chemists and research programs at Procter & Gamble Pharmaceuticals. From 2006 to 2012, he led research programs at the Institutes for Pharmaceutical Discovery (IPD) in Connecticut, USA. He is author of over 30 patents, 100 original publications, review articles and books. For further information, please contact: Molecure S.A. (PR & IR) Marta Borkowska Email: [email protected] +(48) 728 728 143 MEDiSTRAVA Consulting (Financial PR) Frazer Hall, David Dible, Sandi Greenwood, Eleanor Perkin [email protected] +44 (0)203 928 6900 About Molecure Molecure is a clinical stage biotechnology company that uses its world leading medicinal chemistry and biology capabilities to discover and develop first-in-class small molecule drug candidates that directly modulate the function of underexplored protein and RNA targets to treat multiple incurable diseases. Molecure has generated a diverse pipeline of eight distinct programs with the support of leading academic life science institutions globally, including Yale University, Rutgers University, the Flemish Institute for Biotechnology (VIB) in Ghent, the University of Michigan and the International Institute of Molecular and Cell Biology in Warsaw (IIMCB). Molecure's most advanced in-house drug candidate is OATD-01, a first-in-class dual chitinase inhibitor for the treatment of interstitial lung diseases, such as sarcoidosis and idiopathic pulmonary fibrosis, that is Phase II ready. A Phase II trial in patients with sarcoidosis is expected to start in 2023. Our second proprietary candidate is OATD-02, an oral, potent and selective first-in-class, dual arginase inhibitor (ARG1 and ARG2) for the treatment of cancer. Molecure's headquarters and laboratories are located in Warsaw, Poland with an additional laboratory facility in Łódź. The company is listed on the Warsaw Stock Exchange (ticker: MOC). For more information, please visit LinkedIn: Molecure| Twitter: @molecure_sa | YouTube: Molecure SA SOURCE Molecure

NEW YORK and VIENNA, Austria, Dec. 15, 2022 (GLOBE NEWSWIRE) -- HOOKIPA Pharma Inc. (NASDAQ: HOOK, ‘HOOKIPA’), a company developing a new class of immunotherapeutics based on its proprietary arenavirus platform, announced today the promotion of Katia Schlienger, M.D., Ph.D., to Chief Medical Officer and the appointment of Malte Peters, M.D., to its Board of Directors, both effective January 1, 2023. “Katia has had a major impact on HOOKIPA’s clinical development strategy and execution in immuno-oncology therapeutics and vaccines since she joined the Company in 2021. She will be leading the progression of our clinical programs to the next level, specifically our own programs in head and neck and prostate cancers and our partnered programs with Gilead and Roche,” said Joern Aldag, Chief Executive Officer at HOOKIPA. “We are also excited to welcome Malte to our Board. With a background in both oncology and infectious disease, Malte’s experience leading dozens of oncology therapies through the clinic to help patients will be invaluable to HOOKIPA as we advance our pipeline and initiate additional clinical studies.” Dr. Schlienger has been promoted to Chief Medical Officer. She has served as the Company’s Executive Vice President, Clinical Research and Development since July 2022. Prior to that, Dr. Schlienger served as Senior Vice President, Head of Immuno-Oncology Clinical Research and Development from January 2021 to June 2022. She previously worked at Merck & Co., for 14 years, serving in roles of increasing responsibility across early and late-stage clinical development in oncology and vaccines. She received an M.D. from the School of Medicine Lariboisiere Saint-Louis in Paris, France and a Ph.D. in Microbiology/Virology from Paris Diderot University. Dr. Peters serves as Chief Research and Development Officer at MorphoSys and will retire from the company at the end of 2022. He joined MorphoSys in 2017 as Chief Development Officer. In these roles, he oversaw the company’s research and development pipeline, including the design and execution of three pivotal studies. Prior to joining MorpoSys, Dr. Peters was Global Head of Clinical Development of the biopharmaceuticals business unit of Sandoz in Germany. Dr. Peters also spent 12 years in leadership positions at Novartis Oncology, including Vice President, Clinical Head and Site Head for Basel, East Hanover and Shanghai. He was responsible for multiple development programs and clinical trials at Novartis, contributing to the approval of several cancer therapies. Earlier in his career, he held positions at Micromet AG and Merck KgaA, and also served as a research scientist in infectious disease. Dr. Peters is a Member of the Board of Directors at Tango Therapeutics (NASDAQ: TNGX). He is board certified in internal medicine and earned his medical degree from Freie Universität in Berlin, with a postdoctoral fellowship in Toronto. “I am passionate about improving global health, and I have dedicated my career to making new therapies available to individuals with serious and life-threatening conditions,” said Dr. Peters. “I’m honored to join the HOOKIPA Board of Directors and look forward to contributing my expertise to help the company advance its pipeline of novel arenaviral therapeutic candidates so we may have more tools to improve the lives of people with cancer and chronic infectious disease.” About HOOKIPA HOOKIPA Pharma Inc. (NASDAQ: HOOK) is a clinical-stage biopharmaceutical company focused on developing novel immunotherapies, based on its proprietary arenavirus platform, which are designed to mobilize and amplify targeted T cells and thereby fight or prevent serious disease. HOOKIPA’s replicating and non-replicating technologies are engineered to induce robust and durable antigen-specific CD8+ T cell responses and pathogen-neutralizing antibodies. HOOKIPA’s pipeline includes its wholly owned investigational arenaviral immunotherapies targeting Human Papillomavirus 16-positive cancers, prostate cancers, and other undisclosed programs. HOOKIPA is collaborating with Roche on an arenaviral immunotherapeutic for KRAS-mutated cancers. In addition, HOOKIPA aims to develop functional cures of HBV and HIV in collaboration with Gilead. Find out more about HOOKIPA online at . For further information, please contact: Media Investors Instinctif Partners Matt Beck hookipa@instinctif.com Executive Director – Investor Relations +44 (0)20 7457 2020 matthew.beck@hookipapharma.com +1-917-209-6886 Forward Looking Statements Certain statements set forth in this press release constitute “forward-looking” statements within the meaning of the Private Securities Litigation Reform Act of 1995, as amended. Forward-looking statements can be identified by terms such as “believes,” “expects,” “plans,” “potential,” “would” or similar expressions and the negative of those terms. Such forward-looking statements involve substantial risks and uncertainties that could cause HOOKIPA’s research and clinical development programs, future results, performance or achievements to differ significantly from those expressed or implied by the forward-looking statements. Such risks and uncertainties include, among others, the uncertainties inherent in the drug development process, including HOOKIPA’s programs’ early stage of development, the process of designing and conducting preclinical and clinical trials, the regulatory approval processes, the timing of regulatory filings, the challenges associated with manufacturing drug products, HOOKIPA’s ability to successfully establish, protect and defend its intellectual property, risks relating to business interruptions resulting from the coronavirus (COVID-19) disease outbreak or similar public health crises, the impact of COVID-19 on the enrollment of patients and timing of clinical results, and other matters that could affect the sufficiency of existing cash to fund operations. HOOKIPA undertakes no obligation to update or revise any forward-looking statements. For a further description of the risks and uncertainties that could cause actual results to differ from those expressed in these forward-looking statements, as well as risks relating to the business of the company in general, see HOOKIPA’s quarterly report on Form 10-Q for the quarter ended September 30, 2022, which is available on the Security and Exchange Commission’s website at and HOOKIPA’s website at . Investors and others should note that we announce material financial information to our investors using our investor relations website ( ), SEC filings, press releases, public conference calls and webcasts. We use these channels, as well as social media, to communicate with our members and the public about our company, our services and other issues. It is possible that the information we post on social media could be deemed to be material information. Therefore, we encourage investors, the media, and others interested in our company to review the information we post on the U.S. social media channels listed on our investor relations website.