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排名前五的药物类型	数量

多肽偶联药物（PDC）	1

排名前五的靶点	数量

ACE(血管紧张素转化酶)	1

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1

项与 Egyptian Petroleum Research Institute 相关的药物

RXPA380-P

靶点

ACE

作用机制

ACE调节剂

在研机构

Egyptian Petroleum Research Institute [+1]

原研机构

The University of Liverpool [+1]

在研适应症

高血压

非在研适应症-

最高研发阶段临床前

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100 项与 Egyptian Petroleum Research Institute 相关的临床结果

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4,198

项与 Egyptian Petroleum Research Institute 相关的文献（医药）

2025-04-01·Journal of Environmental Sciences

Application of new tetra-cationic imidazolium ionic liquids for capture and conversion of CO2 to amphiphilic calcium carbonate nanoparticles as a green additive in water based drilling fluids

Article

作者: Atta, Ayman M ; Gaffer, Amany K. ; El-Segaey, Abeer A ; Ghiaty, Eman A. ; Atta, Ayman M. ; Shafek, Samir H. ; Ghiaty, Eman A ; Gaffer, Amany K ; El-Segaey, Abeer A. ; Shafek, Samir H

Conversion and capture of carbon pollutants based on carbon dioxide to valuable green oil-field chemicals are target all over the world for controlling the global warming. The present article used new room temperature amphiphilic imidazolium ionic liquids with superior surface activity in the aqueous solutions to convert carbon dioxide gas to superior amphiphilic calcium carbonate nanoparticles. In this respect, tetra-cationic ionic liquids 2-(4-dodecyldimethylamino) phenyl)-1,3-bis (3-dodecyldimethylammnonio) propyl) bromide-1-H-imidazol-3-ium acetate and 2-(4-hexyldimethylamino) phenyl)-1,3-bis(3-hexcyldimethylammnonio) propyl) bromide-1 H-imidazol-3-ium acetate were prepared. Their chemical structures, thermal as well as their carbon dioxide absorption/ desorption characteristics were evaluated. They were used as solvent and capping agent to synthesize calcium carbonate nanoparticles with controlled crystalline lattice, sizes, thermal properties and spherical surface morphologies. The prepared calcium carbonate nanoparticles were used as additives for the commercial water based drilling mud to improve their filter lose and rheology. The data confirm that the lower concentrations of 2-(4-dodecyldimethylamino) phenyl)-1,3-bis (3-dodecyldimethylammnonio) propyl) bromide-1-H-imidazol-3-ium acetate achieved lower seawater filter lose and improved viscosities.

2025-01-01·Journal of Molecular Structure

The performance of hydrophilic moieties in synthesized fluorinated cationic surfactants on corrosion inhibition of carbon steel pipelines

作者: Mohamed, Moshera Z. ; Sami, Radwa M. ; Abdelhafiz, Fatma M.

Compared with traditional hydrocarbon surfactants, fluorinated surfactants exhibit unique characteristics such as reduced surface tension, enhanced efficacy in reducing interfacial tension, dual hydrophobic and oleophobic nature, increased thermal stability, and superior chem. resistance.These characteristics make them a favorite material for many kinds of applications.This study aims to highlight the synthetic route for three novel cationic fluorinated surfactants (CFS) and applied them in the oilfield as corrosion inhibitors.Characterization of the prepared surfactants took place using different spectroscopic techniques.The influence of hydrophilic moieties on the micellar characteristics of ionic surfactants that have the same hydrophobic fluorinated chains are investigated in this research.Also, an evaluation of the influence of these groups on thermodn. parameters was carried out.The metal corrosion inhibition efficiency of the CFS was studied in acidic medium by three different techniques, including potentiodynamic polarization, electrochem. impedance spectroscopy (EIS), and weight loss procedures, at three different temperature ranges (25, 40, and 60 °C).The achieved results displayed the inhibition efficiency of the metal corrosion that was elevated by increasing both the CFS′s concentration and the applied temperature values.The highest level of inhibition, reaching 97.48 %, was achieved at a concentration of 700 ppm (ppm) and a temperature of 60 °C.Furthermore, it was noticed that the charge transfer resistance value was raised; however, the constant phase element was decreased with increasing the CFS concentrationsThe CFS regards an excellent and mixed-type corrosion inhibitor.The adsorption of CFS has agreed the Langmuir′s adsorption isotherm and was related to chemisorption.SEM photos show a good CS surface in the presence of CFS vs. the absence of them.

2024-12-01·Fuel

The pyrolytic distillation of waste lubricants with waste oilfield scale into value-added fuel

作者: Attia, Sayed K. ; Osman, Doaa I. ; Elsayed, Asmaa. E. ; Mohamady Ghobashy, Mohamed ; Rashad, Ahmed M.

The ever-increasing generation of waste materials has become a major environmental concern, highlighting the need for sustainable waste management strategies.This study explores the catalytic pyrolysis of waste lubricant oils using a waste oilfield scale as a low-cost solid catalyst to produce value-added fuel products.The pyrolytic distillation of waste engine oil was carried out in a manual distillation unit, employing a calcium carbonate (CaCO₃) scale as a catalyst under various reaction conditions.Distillation experiments were conducted at 300 °C, 320 °C, and 350 °C, with and without adding NaOH and CaCO₃ catalysts.The distillate fractions were characterized, and their properties were compared to standard fuel specifications.The results demonstrated that increasing the pyrolysis temperature and employing CaCO₃ as a catalyst significantly enhanced the distillate yield and improved key fuel properties.At 350 °C, the distillate yield reached 56 % with 4 g of CaCO₃, exhibiting desirable d. (0.8049 g/cm³), viscosity (2.31 cSt at 40 °C), sulfur content (0.43 wt%), and a calorific value of 43,152 kJ/kg.Further, the distillate fractions were separated into gasoline (80-150 °C), kerosene (180-270 °C), and gas oil/diesel (270-350 °C) ranges, with the diesel fraction showing a promising cetane number of 51.The catalytic pyrolysis fuel (CPF) obtained from distillation with 4 g CaCO₃ at 350 °C, followed by bleaching with CaO, exhibited excellent properties, including a d. of 0.8297 g/cm³, viscosity of 2.71 cSt at 40 °C, pour point of -12 °C, sulfur content of 0.201 wt%, and a calorific value of 43,961 kJ/kg.The GC anal. revealed a paraffin-rich composition in the desired fuel ranges, contributing to the desirable fuel properties.

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100 项与 Egyptian Petroleum Research Institute 相关的转化医学

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