Delving into the Latest Updates on Shahid Chamran University of Ahvaz with Synapse

概览

疾病领域	数量

内分泌与代谢疾病	1
免疫系统疾病	1
肿瘤	1

排名前五的药物类型	数量

小分子化药	1

排名前五的靶点	数量

Nrf2 x STAT3	1

关联

1

项与 Shahid Chamran University of Ahvaz 相关的药物

Dimethyl itaconate

二甲酯衣康酸

靶点

Nrf2 x STAT3

作用机制

Nrf2调节剂 [+1]

在研机构

天津医科大学 [+2]

原研机构-

在研适应症

多囊卵巢综合征 [+2]

非在研适应症-

最高研发阶段临床前

首次获批国家/地区-

首次获批日期-

17

项与 Shahid Chamran University of Ahvaz 相关的临床试验

IRCT20240222061082N1 / Recruiting临床3期IIT

The Effect of Combined Ointment of Alpha-Pinene and Frankincense in Rheumatoid Arthritis on Reducing Pain in Osteoarthritis

开始日期2024-03-10

申办/合作机构

Shahid Chamran University of Ahvaz

IRCT20230709058725N1 / CompletedN/AIIT

comparison of the Effectiveness of transition to parenthood programs the Family Foundation(FF) with Couples Care for Parents(CCP) on subjective well-being, marital conflict, and marital satisfaction new parents.

开始日期2023-11-05

申办/合作机构

Shahid Chamran University of Ahvaz

IRCT20231013059706N1 / RecruitingN/AIIT

Developing an educational program based on psychological empowerment and comparing its effectiveness with cognitive behavioral therapy on psychological flexibility, academic hope and life satisfaction of adolescents

开始日期2023-10-23

申办/合作机构

Shahid Chamran University of Ahvaz

100 项与 Shahid Chamran University of Ahvaz 相关的临床结果

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0 项与 Shahid Chamran University of Ahvaz 相关的专利（医药）

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9,251

项与 Shahid Chamran University of Ahvaz 相关的文献（医药）

2024-12-31·Energy Sources, Part A: Recovery, Utilization, and Environmental Effects

Effect of temperature variation on the accurate prediction of bottom-hole pressure in well drilling

作者: Daneh-Dezfuli, Alireza ; Hajidavalloo, Ebrahim ; Falavand Jozaei, Ali

Knowing the effects of different parameters on the drilling fluid is an essential part of a successful and safe drilling operation.High pressure and high temperature conditions have opposing effects on the fluid d. which has an important effect on the bottom-hole pressure.So for estimating precise bottom-hole pressure, it is essential to take into account these opposite effects on drilling fluid compression or expansion.In this study, Bingham-plastic model is considered as drilling fluid to simulate drilling operation and develop temperature and pressure distribution through the wellbore.The effects of variation in drilling fluid flow rate, drilling fluid sp. heat and inlet mud temperature are explored and discussed for an oil-based mud.Also, the effects of frictional pressure loss, pressure loss in the drill bit and, drill string rotation are considered as internal heat sources in the wellbore.Results show that thermal interaction is required for accurate prediction of the bottom-hole pressure.Variations of different parameters change temperature distribution in the wellbore which consequently changes the bottom-hole pressure.The results show that considering the variation of rheol. properties, bottom-hole pressure prediction may change as much as 685 psi (about 2.30%) which is considerable.Model predictions were compared with the field data for validation of the model.

2024-12-31·Systems Biology in Reproductive Medicine

Study of the genomics and transcriptomics profiles of male-infertility genes in human prostate cancer: an in silico analysis

Article

作者: Tahmasebi-Birgani, Maryam ; Ghandil, Pegah ; Hajjari, Mohammadreza ; Said Ali-Samani, Farima ; Shahrisa, Arman

The World Health Organization has considered the infertility as an international public health problem. Infertility affect nearly 1 in 7 couples and male component contributes to 50% of infertility cases. There is a clear link between male infertility and some cancers such as testicular germ cell, prostate and colon cancers. Two possibilities support this finding: 1) Cancer treatments can affect the fertility factors 2) Genetic profile of infertility genes have been altered in cancer patients. Although the previously published researches have mostly focused on the first factor, no article has yet confirmed the role of genetic factors. In this in silico study, we collected the large number of genes (n = 17703) involved in infertility. These genes were collected from NGS panel tests of male infertility and comprehensive literature review or online data base. The Prostate Adenocarcinoma genomic and transcriptomics raw data were downloaded from the cBioPortal Cancer dataset. This included with 494 patients of Prostate Cancer with 494 mutation data, 489 with CNA and 493 with RNA seqV2 data. TCGA RNA-Seq raw data was extracted in R using the cgdsr extension package with a threshold of ±2 relative to normal samples. The observed data showed that male infertility genes have been distributed through the human genome. Among the 17703 analyzed genes of this study, the genomic profile of three genes including OR9Q1, H4C6 and PSG7 were changed approximately in 100% of (n = 493) patients. In most of patients (>98%), genetic alteration was related to change in gene expression. In conclusion, this study showed that the genomic and transcriptomics patterns of some male-infertility genes are notably altered in patients of prostate cancer and suggested a possible role of genetic factors in occurrence of infertility in cancer patients. Our information can be used as a source for the design of genetic database of male-infertility.

2024-12-31·Geomatics, Natural Hazards and Risk

Assessment of soil erosion and sediment delivery ratio in the Arghandab Catchment, Kandahar Province, Afghanistan by using GIS-based RUSLE method

作者: Tayfur, Gokmen ; Ansari, Ahmad ; Mohammadi, Shahin

100 项与 Shahid Chamran University of Ahvaz 相关的药物交易

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100 项与 Shahid Chamran University of Ahvaz 相关的转化医学

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