Comparative study to know the efficacy and safety of stromal vascular fraction-enriched platelet-rich plasma therapy versus platelet rich plasma therapy in the treatment of Androgenetic alopecia - NIL

开始日期2025-05-01

申办/合作机构

Rajarajeswari Medical College & Hospital

CTRI/2024/09/074198

/ Not yet recruiting临床4期IIT

A Randomized Comparative Study of the Sniffing Position with Simple Head Extension for Visualization of Glottis and Difficulty in Intubation during Direct Laryngoscopy - NIL

开始日期2024-10-01

申办/合作机构

Rajarajeswari Medical College & Hospital

CTRI/2024/08/072540

/ Not yet recruitingN/AIIT

To determine the efficacy of dexmedetomidine and dexamethasone nebulisation in preventing sore throat in patients undergoing general anesthesia: A randomised double blind comparative study - Nil

开始日期2024-08-26

申办/合作机构

Rajarajeswari Medical College & Hospital

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项与 Rajarajeswari Medical College & Hospital 相关的文献（医药）

2025-04-01·Journal of Psychiatric Research

Association between smartphone addiction and sedentary behaviour amongst children, adolescents and young adults: A Systematic Review and meta-analysis

Review

作者: Priyan, Shanthosh ; Kailasam, Jayashree Guka ; Krishnamoorthy, Yuvaraj ; U, Sharath ; Ganesh, Karthika ; Nambirajan, Murali Krishnan ; Kannan, Suthanthira ; Vidusha, Karavadi ; Govindan, Dhanajayan

BACKGROUNDThe rapid proliferation of smartphones has raised concerns about their impact on physical activity levels, particularly among younger demographics. While smartphones offer numerous benefits, there is growing evidence to suggest that excessive use may lead to sedentary behaviours, potentially impacting physical health adversely. Hence, this review was done to explore the association between smartphone addiction and reduced physical activity amongst children, adolescents and young adults.METHODSThis meta-analysis systematically reviewed ten studies involving 5195 participants. We employed a random-effects model with DerSimonian-Laird estimation for tau² to calculate pooled odds ratios (ORs). Subgroup analyses were conducted based on geographical regions, risk of bias, and different measurement tools to assess the robustness and variability of the findings. Publication bias was assessed using funnel plots, Egger's test, and the trim-and-fill method.RESULTSThe analysis revealed a significant association between smartphone addiction and reduced physical activity, with a pooled OR of 2.19 (95% CI: 1.34 to 3.57, p = 0.002). Notably, subgroup analyses demonstrated a stronger association in studies from the Middle-Eastern region (OR = 4.75; p = 0.026) and among studies employing alternative standardized scales (OR = 3.32; p = 0.044). Sensitivity analyses confirmed the robustness of these findings, and although potential publication bias was detected, it did not materially affect the overall estimates.CONCLUSIONSSmartphone addiction is significantly linked with reduced physical activity among younger populations, underscoring the need for targeted public health interventions and longitudinal studies to elucidate causal mechanisms. These findings highlight that mitigating excessive smartphone use may be a critical component in promoting active lifestyles.

2025-02-01·Indian Journal of Anaesthesia

Thoracic spinal anaesthesia – An effective alternative to general anaesthesia in breast surgeries: A randomised, non-blinded study

Article

作者: Karthik, G. S. ; Amabareesha, M. ; Sudheer, R. ; Kumar, M. Dilip ; Monisha, T. S. ; Srinivasan, Rangalakshmi

2025-01-09·Cureus

Using Lung Ultrasound Combined With N-terminal Pro-brain Natriuretic Peptide to Differentiate Acute Heart Failure From Chronic Obstructive Pulmonary Disease and Asthma in Emergency Department Patients Experiencing Acute Shortness of Breath

Article

作者: Kaeley, Nidhi ; Vasisht, Shivani ; Aravindan, Nisarg ; Datta, Soumya Subhra ; Sharma, Ankit

INTRODUCTIONDifferentiating acute heart failure (AHF) from chronic obstructive pulmonary disease (COPD) or asthma is essential for prompt and appropriate treatment in patients presenting with acute shortness of breath in the emergency department (ED).AIMThis study aimed to evaluate the diagnostic accuracy of bedside lung ultrasound, N-terminal pro-brain natriuretic peptide (NT-proBNP) level, and clinical criteria (using the modified Boston criteria) for differentiating AHF from COPD/asthma.MATERIALS AND METHODSThis prospective cohort study was conducted in the Emergency Medicine Department of the All India Institute of Medical Sciences, Rishikesh, from June 2023 to December 2023. Patients presenting with acute shortness of breath were managed using clinical assessment (according to modified Boston criteria), lung ultrasound, and NT-proBNP measurements.RESULTSOut of 104 patients, 45 were diagnosed with AHF, and 59 had pulmonary-related causes of shortness of breath. Lung ultrasound demonstrated a sensitivity of 100%, specificity of 62.3%, negative predictive value (NPV) of 100%, and positive predictive value (PPV) of 65.15% for diagnosing heart failure. NT-proBNP, with a cutoff value of 500 pg/mL, showed 100% sensitivity, 91.8% specificity, 100% NPV, and 89.58% PPV. The Boston modified criteria had a sensitivity of 76.74%, specificity of 88.52%, NPV of 84.38%, and PPV of 82.5%. A comparison of these three diagnostic methods revealed significant differences between the ultrasound findings and both NT-proBNP and modified Boston criteria (p < 0.05). The combination of ultrasound signs and NT-proBNP yielded 100% sensitivity, specificity, NPV, and PPV.CONCLUSIONSThe integration of lung ultrasound, NT-proBNP level, and clinical criteria provides a reliable and rapid approach for differentiating AHF from COPD/asthma in the ED.

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