The purpose of this study is to examine the effects of normal vs. protein-rich afternoon snacks on appetite control, satiety, and reward-driven eating (particularly in the evening) in young people. Indices of attention and mood will also be assessed.
Study hypotheses include the following:
The consumption of a high-protein, soy-rich afternoon snack will lead to significant improvements in appetite control and satiety, reductions in food motivation and reward, and will delay the drive to eat in normal to overweight young people.
The consumption of a high-protein, soy-rich afternoon snack will lead to reduced unhealthy, evening snacking, particularly on foods high in fat and/or sugar, in normal to overweight young people.
The daily consumption of a high-protein, soy-rich afternoon snack will lead to significant improvements in afternoon alertness, concentration, fatigue, and well-being in normal to overweight young people.

开始日期2013-01-01

申办/合作机构

University of Missouri

[+1]

NCT01358318 / CompletedN/A

Effect of Addition of Soy Protein and Soy Fiber to a Snack Bar on Satiety and Food Intake

The purpose of this study is to determine whether ingestion of a bar containing either added soy protein or soy fiber or both, increases subjective and objective measures of satiety compared to a control bar.

开始日期2011-02-01

申办/合作机构

Solae LLC

[+1]

NCT01749202 / CompletedN/A

Effects of Stearidonic Acid-Containing Foods on Eicosapentaenoic Acid Levels in Red Blood Cells and Omega-3 Index

The purpose of this study is to assess the effect of stearidonic acid when used as a food ingredient on eicosapentaenoic enrichment of red blood cell membranes and Omega-3 Index in men and women.

开始日期2010-08-01

申办/合作机构

Solae LLC

[+1]

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2017-01-01·Sustainable Protein Sources

Soy Protein

作者: M. Thrane ; P.V. Paulsen ; M.W. Orcutt ; T.M. Krieger

Abstract Soybeans have provided protein through traditional foods into Asian diets for over a thousand years. Today, new processes enable isolation of soybean proteins expanding their potential for food applications. Various environmental impacts associated with isolated soy protein (ISP) have recently been analyzed in a third-party review and ISO 14040/44 compliant life cycle assessment (LCA). The environmental analysis demonstrates that the carbon footprint of ISP produced by DuPont Nutrition & Health amounts to only a few kg carbon dioxide equivalents (CO2e) per kg protein, from cultivation to edible product as coined “cradle-to-gate.” LCA screenings show that the carbon footprints of animal-based protein products are, respectively, 8–80 times and 3–30 times higher than for the analyzed ISP, depending on the type of animal protein and the applied LCA methodology (consequential vs attributional modeling). Advances in processing technologies and applications have created new opportunities for human consumption of plant proteins; in many cases, these opportunities exist in foods combining animal and plant proteins for economic, functional, and nutritional advantage.

2014-02-01·BMJ Open4区 · 医学

Effect of a 6-month vegan low-carbohydrate (‘Eco-Atkins’) diet on cardiovascular risk factors and body weight in hyperlipidaemic adults: a randomised controlled trial

4区 · 医学

ArticleOA

作者: Dorothea A Faulkner ; Tracy C K Leong ; Julia M W Wong ; William Singer ; Ratna Mukherjea ; David J A Jenkins ; Cyril W C Kendall ; Ed Vidgen ; Gregory Paul ; Elaine S Krul ; Amin Esfahani ; Vivian W Y Ng

ObjectiveLow-carbohydrate diets may be useful for weight loss. Diets high in vegetable proteins and oils may reduce the risk of coronary heart disease. The main objective was to determine the longer term effect of a diet that was both low-carbohydrate and plant-based on weight loss and low-density lipoprotein cholesterol (LDL-C).Design, setting, participantsA parallel design study of 39 overweight hyperlipidaemic men and postmenopausal women conducted at a Canadian university-affiliated hospital nutrition research centre from April 2005 to November 2006.InterventionParticipants were advised to consume either a low-carbohydrate vegan diet or a high-carbohydrate lacto-ovo vegetarian diet for 6 months after completing 1-month metabolic (all foods provided) versions of these diets. The prescribed macronutrient intakes for the low-carbohydrate and high-carbohydrate diets were: 26% and 58% of energy from carbohydrate, 31% and 16% from protein and 43% and 25% from fat, respectively.Primary outcomeChange in body weight.Results23 participants (50% test, 68% control) completed the 6-month ad libitum study. The approximate 4 kg weight loss on the metabolic study was increased to −6.9 kg on low-carbohydrate and −5.8 kg on high-carbohydrate 6-month ad libitum treatments (treatment difference (95% CI) −1.1 kg (−2.1 to 0.0), p=0.047). The relative LDL-C and triglyceride reductions were also greater on the low-carbohydrate treatment (treatment difference (95% CI) −0.49 mmol/L (−0.70 to −0.28), p<0.001 and −0.34 mmol/L (−0.57 to −0.11), p=0.005, respectively), as were the total cholesterol:HDL-C and apolipoprotein B:A1 ratios (−0.57 (−0.83, −0.32), p<0.001 and −0.05 (−0.09, −0.02), p=0.003, respectively).ConclusionsA self-selected low-carbohydrate vegan diet, containing increased protein and fat from gluten and soy products, nuts and vegetable oils, had lipid lowering advantages over a high-carbohydrate, low-fat weight loss diet, thus improving heart disease risk factors.Trial Registrationclinicaltrials.gov (http://www.clinicaltrials.gov/), #NCT00256516.

2013-12-01·Lipids in Health and Disease3区 · 医学

Effect of stearidonic acid-enriched soybean oil on fatty acid profile and metabolic parameters in lean and obese Zucker rats

3区 · 医学

ArticleOA

作者: John M Casey ; Dustie N Butteiger ; Jeremy E Davis ; William J Banz ; Daniel A Goldstein ; Elaine S Krul

AbstractBackgroundConsumption of marine-based oils high in omega-3 polyunsaturated fatty acids (n3PUFAs), eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) is known to protect against obesity-related pathologies. It is less clear whether traditional vegetable oils with high omega-6 polyunsaturated fatty acid (n6PUFA) content exhibit similar therapeutic benefits. As such, this study examined the metabolic effects of a plant-based n3PUFA, stearidonic acid (SDA), in polygenic obese rodents.MethodsLean (LZR) and obese Zucker (OZR) rats were provided either a standard westernized control diet (CON) with a high n6PUFA to n3PUFA ratio (i.e., 16.2/1.0) or experimental diet modified with flaxseed (FLAX), menhaden (FISH), or SDA oil that resulted in n6PUFA to n3PUFA ratios of 1.7/1.0, 1.3/1.0, and 1.0/0.8, respectively.ResultsAfter 12 weeks, total adiposity, dyslipidemia, glucose intolerance, and hepatic steatosis were all greater, whereas n3PUFA content in liver, adipose, and muscle was lower in OZR vs. LZR rats. Obese rodents fed modified FISH or SDA diets had lower serum lipids and hepatic fat content vs. CON. The omega-3 index (i.e., ΣEPA + DHA in erythrocyte membrane) was 4.0, 2.4, and 2.0-fold greater in rodents provided FISH, SDA, and FLAX vs. CON diet, irrespective of genotype. Total hepatic n3PUFA and DHA was highest in rats fed FISH, whereas both hepatic and extra-hepatic EPA was higher with FISH and SDA groups.ConclusionsThese data indicate that SDA oil represents a viable plant-derived source of n3PUFA, which has therapeutic implications for several obesity-related pathologies.

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