Study on comparison of prophylactic phenylephrine infusion versus intravenous ramosetron on hypotension during spinal anaesthesia for herniorhhaphy , hernioplasty : A Randomized controlled trial - NIL

开始日期2024-09-30

申办/合作机构

Rajendra Institute of Medical Sciences

CTRI/2024/08/072368 / Not yet recruiting临床4期IIT

Study on comparison of postoperative analgesic effect of gel foam soaked Ropivacaine 0.25% & with gel foam soaked with Ropivacaine 0.25% &Dexmedetomidine in lumbar laminectomy surgeries - NIL

开始日期2024-08-23

申办/合作机构

Rajendra Institute of Medical Sciences

CTRI/2024/08/072257 / Not yet recruiting临床4期IIT

Effect of pretreatment with MgSO4 in decreasing succinyl choline induced fasciculations, post operative myalgia and its effect on serum pottasium - nil

开始日期2024-08-20

申办/合作机构

Rajendra Institute of Medical Sciences

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899

项与 Rajendra Institute of Medical Sciences 相关的文献（医药）

2024-10-01·Journal of Stomatology, Oral and Maxillofacial Surgery

Efficacy of photobiomodulation in the management of oral Lichen Planus in comparison to topical corticosteroids: Systematic review, meta-analysis, and GRADE-based assessment of certainty of evidence

Review

作者: Mahuli, Amit Vasant ; Mahuli, Simpy Amit ; Ul Haque, Zeya ; Rai, Arpita ; Shree, Priya

BACKGROUNDThere is an urgent need to update the evidence available on the efficacy of photobiomodulation (PBM) in comparison to topical corticosteroids in the management of Oral Lichen Planus (OLP).METHODSCochrane Oral Health's Trials Register, Cochrane Central Register of Controlled Trials in the Cochrane Library, MEDLINE Pubmed, SCOPUS, Lilacs and Google Scholar were searched. Other sources included US National Institutes of Health Ongoing Trials Register, World Health Organization International Clinical Trials Registry Platform and Clinical Trial Registry - India were searched using variations of the keywords "Laser" and "Oral Lichen Planus". Randomized controlled trials comparing PBM and topical corticosteroids in the resolution of pain among OLP patients were included. The studies were assessed using the Cochrane Risk-of-Bias assessment tool. Publication bias was assessed using a funnel plot, and the certainty of evidence was evaluated according to the GRADE guidelines.RESULTSTen studies were included for qualitative assessment and of these eight were included in the meta-analysis. The included studies used laser parameters of varying strengths and duration. Meta-analysis favoured PBM (n = 274, MD =-0.48, CI -0.66- -0.30) for pain score. No adverse effects were reported for laser therapy. There was high heterogeneity and moderate certainty of evidence, and most studies had a high risk of bias.CONCLUSIONThere is improvement in the clinical parameters of OLP when treated with PBM in comparison to topical corticosteroids. However, the strength of the evidence for these findings in limited. It is recommended to conduct better long-term trials with large sample size.

2024-10-01·Annals of African Medicine

Posttraumatic Anterior Hip Dislocation with Ipsilateral Comminuted Intertrochanteric Fracture: A Rare Case Report

Article

作者: Kundu, Sabyasachi ; Prabhat, Vinay ; Topno, Rohit ; Prasad, Verma Dipak Kumar Prakash

Hip joint is a ball and socket type of joint and its anatomic features makes it very stable. However, Incidence of hip dislocation has increased recently due to high energy trauma like road traffic accident, fall from height etc. It is usually associated with fracture of femoral head, neck, shaft and acetabular wall. Association of ipsilateral intertrochantric fracture is exceedingly rare and only a few case reports are available in the literature. We are presenting a rare case report of neglected anterior hip dislocation with ipsilateral comminuted intertrochanteric fracture managed with hemiarthroplasty using long cemented distal press-fit revision stem. A 66-year-old male presented to our outpatient department with history of fall from a tree 22 days back with pain in right hip and inability to bear weight on right lower limb. Radiographs were suggestive of anterior hip dislocation with fracture of ipsilateral comminuted intertrochanteric fracture of right side. Anterior hip dislocation with ipsilateral intertrochanteric fracture is a very rare entity, and only a few case reports are available in the literature. Management includes early open reduction and fixation to achieve optimal outcomes, but doing primary arthroplasty is also a viable option especially in neglected cases as there is high chances of avascular necrosis and secondary osteoarthritis of the hip joint later on.

2024-10-01·Annals of African Medicine

Comparison of Double Endobutton and Clavicular Hook Plate in Acromioclavicular Joint Disruption: A Systematic Review and Meta-analysis

Review

作者: Halder, Subhajit ; Kumar, Amit ; Rani, Sudha ; Gupta, Govind Kumar ; Kumar, Tushar ; Chakraborty, Ratnajeet

Background:Acromioclavicular joint (ACJ) disruptions are corrected by surgery either with an endobutton or a hook plate. The results in the long term were found to be similar in many randomized controlled trials. This study aims to conduct a meta-analysis to evaluate the functional outcome and complications of double endo button versus clavicular hook plate (CHP) for ACJ disruption (Rockwood types III–VI).Materials and Methods:Two authors independently searched related articles from electronic databases (PubMed, Google Scholar, MEDLINE, SCOPUS, and Web of Science) till January 26, 2022. The data were extracted from the related articles and analyzed by Stata software. For bias calculation of each study, the Newcastle–Ottawa scale and the RevMan 5.4 software were used.Results:14 cohort studies, 2 randomized control trial studies, and 1 case–control study including patients were selected in this meta-analysis. The results of our study showed a significantly higher Constant–Murley Score (WMD 5.79, 95% confidence interval [CI] 2.23–9.36), Visual Analog Scale (WMD− 0.63, 95% CI [−0.79, −0.46]) and University of California at Los Angeles shoulder score (UCLA) scale (WMD 3.32, 95% CI [2.87, 3.77]) for double endobutton group. At the same time, some complications like implant failure were more common in the double endobutton group.Conclusion:This meta-analysis shows better functional and clinical outcomes of shoulder joint for the treatment of acromioclavicular joint (ACJ) disruption cases (Rockwood types III–VI) with no need for secondary operation, unlike the CHP. Complications like subacromial erosion, ACJ arthrodesis, and infection rate are higher in the CHP group, whereas the chance of implant failure is higher in the double endobutton group.

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