The HPLC method for the determination of ferulic acid in Qiying Yuyang granules was presented.The YWG C18 column was used with the mobile phase of methanol-0.066M Na2HPO4 solution (pH 2.5, adjusted by H3PO4) (40:60).The flowing rate was 1.00 mL min-1 and the detection wavelength was 320 nm.The calibration curve was linear in the range of 0.08-0.32 μg, and the average recovery was 98.9% with RSD of 1.54%.