This is a randomised, double-blind, placebo-controlled study that recruited 110 participants. The objectives of this study are to determine the dietary intake levels of lutein and zeaxanthin among precipitants. In additionally, this study also aimed to determine the efficacy of twinkle eyez supplementation in improving ocular health and immunity. The participant are required to take one sachet of twinkle eyez supplements or placebo for 20 days. The outcomes were assessed by food frequency questionnaire (FFQ), Ocular Surface Disease Index (OSDI), the Immune Status Questionnaire (ISQ), and the Visual Analogue Scale (VAS).

开始日期2024-07-01

申办/合作机构

UCSI University

NCT06524271 / CompletedN/A

Effect of Fermented Soybean (FSB) Supplementation on Gas-troesophageal Reflux Disease (GERD)

Gastroesophageal reflux disease (GERD) is a prevalent chronic condition affecting the well-being of both adults and children in general medical practice. Research on the effects of fermented soy-bean (FSB) supplementation in managing GERD is relatively new, with limited studies available. Existing research often lacks sufficient dosing regimens and study durations to differentiate be-tween transient placebo effects and sustained benefits. In this study, the beneficial effects of FSB supplementation were investigated in 50 voluntary participants. Participants were required to take 1g of FSB supplement once daily for twelve weeks. GERD symptoms were evaluated using the Reflux Disease Questionnaire (RDQ), while inflammatory markers, including interleukin-4 (IL-4), interleukin-6 (IL-6), and interleukin-8 (IL-8), were measured to assess inflammation. The Quality of Life in Reflux and Dyspepsia (QOLRAD) questionnaire was used to evaluate partici-pants' quality of life. Results indicated that FSB supplementation significantly (P<0.05) alleviated heartburn and regurgitation symptoms and reduced levels of IL-4, IL-6, and IL-8, indicating a notable anti-inflammatory effect. Additionally, significant (P<0.05) improvements were observed in QOLRAD scores, particularly in vitality, emotional distress, and physical/social functioning. Collectively, our findings support the use of FSB as an adjuvant approach in managing GERD, with notable improvements in patients' quality of life.

开始日期2023-11-01

申办/合作机构

UCSI University

JPRN-UMIN000046962 / SuspendedN/AIIT

Home gardening programme for the improvement of vegetable consumption among urban poor children aged 9 to 12 years in Kuala Lumpur, Malaysia - Home gardening programme for the improvement of vegetable consumption among urban poor children aged 9 to 12 years in Kuala Lumpur, Malaysia

开始日期2022-09-01

申办/合作机构

UCSI University

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项与 UCSI University 相关的文献（医药）

2024-12-31·Energy Sources, Part A: Recovery, Utilization, and Environmental Effects

Effect of combined exhaust gas recirculation and retarded injection timing on diesel engine operated distilled waste plastic oil blend

作者: Kit Ang, Chun ; Chinnappan, Ramesh ; Chandran, Mohanraj

This work is focused to improve the engine operation along with reducing the emission in diesel engine, operated using optimal distilled waste plastic oil blend (D1WPO30).Here, the exhaust gas was recirculated to the engine during run under standard and retarded injection timings about 23° and 17° bTDC.The percentages of exhaust gas recirculation (EGR) were 10 vol% and 20 vol%.In both cases, the engine was operated using diesel and distilled waste plastic oil blends with an optimized ratio of 30 vol%.The engine performance, combustion, and exhaust parameters were analyzed and compared with normal operations, and the brake thermal efficiency (BTE) of the engine was found higher about 10% with retarded and EGR operation than a normal operation with 23° bTDC.The specific fuel consumption was found increased by about 5% than normal operations due to the re-burning of unburned hydrocarbon.Both cylinder pressure and heat release rate were found to decrease with an increase in EGR rates, which was mainly due to reduced cylinder temperatureThe NOx and other emission parameters like carbon monoxide and unburned hydrocarbon were found a decrease from 8 to 16% due to the combined effect of retarded and EGR operation than standard D1WPO30 operations.The NOx was reduced upto 5% with EGR operations due to lower cylinder temperature caused by the increased heat capacity of the working mixture

2024-12-31·European Journal of Psychotraumatology

Dynamic networks of complex posttraumatic stress disorder and depression among college students with childhood trauma: insights from cross-sectional and cross-lagged panel network analysis

Article

作者: Liu, Mingxiao ; Liu, Aiyi ; Zhang, Lake Mozi ; Peng, Yu ; Ren, Yizhen

Background and Objective: There is a current research gap regarding the symptom structure and underlying causal relationships between complex posttraumatic stress disorder (CPTSD) and depressive symptoms. This longitudinal study used a cross-sectional network and cross-lag panel network (CLPN) to examine how CPTSD and depression symptoms interact over time in Chinese college students with childhood trauma.Methods: From 18,933 college students who took part in 2 surveys 12 months apart, 4006 participants (mean age: 20.07 ± 2.04) who reported childhood trauma were screened. Within this sample, there were 2354 (58.8%) males and 1652 (41.2%) females.Results: In the one-year interval CLPN model, it was found that depressive symptoms may precede other symptoms. Specifically, negative emotions and negative self-evaluations are more likely to predict subsequent symptoms. Conversely, in CPTSD, symptoms related to fear and anxiety, such as avoidance, intrusion, and hyperarousal, are more frequently activated by other symptoms, including negative emotionsConclusions: This finding offers a novel perspective on the interplay between CPTSD and depression, extending the existing theory. From a clinical standpoint, the points of intervention for comorbidity between depression and CPTSD who have experienced childhood trauma differ across different stages.

2024-12-31·Energy Sources, Part A: Recovery, Utilization, and Environmental Effects

Effect of nano cerium oxide additive with tire oil blends on diesel engine combustion and emissions parameters with soot morphology analysis

作者: Chinnappan, Ramesh ; N, Parthipan ; Chandran, Mohanraj ; Ang, Chun Kit

This article focused to analyze the effect of cerium oxide (CeO₂) as an additive to distilled tire oil blends (DTO30) in diesel engine operation.The nano cerium oxide (morphol.: spherical with a size of 20 nm) was added with proportions of 50 mg/L and 100 mg/L to the distilled tire oil blend.Addition of this CeO₂ to tire oil blends tend to reduce emission, soot suspension time along with improved engine performance.The extraction of tire oil was carried out by thermal pyrolysis and distilled with a fractional distillation column apparatusThe diesel engine was tested and the results were analyzed based on performance, combustion and emission with soot morphol. anal. using transmittance electron microscope (TEM).The results with CeO₂ operations show that the brake thermal efficiency was increased up to 14% with 100 mg/L and brake specific fuel consumption was reduced significantly compared with DTO30 without CeO₂.The cylinder pressure and heat release rate were reduced by shortening the ignition delay.Also the NOx, CO, and UHC were reduced between 15% and 22% with CeO₂ additives compared to normal operations.Also, the reduction of soot particle has found up to 20% while using additives.In TEM morphol., the size of soot particulates was increased because its intensity to bind around the cerium oxide, the size was increased up to 200 nm to 300 nm than normal size.

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