Delving into the Latest Updates on Alantos Pharmaceuticals AG with Synapse

概览

排名前五的药物类型	数量

小分子化药	1

排名前五的靶点	数量

MMP13(基质金属蛋白酶-13)	1

关联

1

项与 Alantos Pharmaceuticals AG 相关的药物

MMP13 inhibitors(Alantos Pharmaceuticals)

靶点

MMP13

作用机制

MMP13抑制剂

在研机构

Alantos Pharmaceuticals AG

原研机构

Alantos Pharmaceuticals AG

在研适应症

骨关节炎

非在研适应症-

最高研发阶段临床前

首次获批国家/地区-

首次获批日期-

100 项与 Alantos Pharmaceuticals AG 相关的临床结果

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0 项与 Alantos Pharmaceuticals AG 相关的专利（医药）

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1

项与 Alantos Pharmaceuticals AG 相关的文献（医药）

Methods and Principles in Medicinal Chemistry

Dynamic combinatorial diversity in drug discovery

作者: Lehn, Jean-Marie ; Hochguertel, Matthias

A review.Modern combinatorial libraries are characterized by the generation of numerous different, but structurally related compounds that exist discretely as static entities, under similar conditions, in a systematic manner.These combinatorial arrays can be produced in a parallel fashion, either as a library of individual compounds or as pooled mixturesIn applying a parallel format, the compounds are handled individually in separated compartments.This removes difficulties associated with compound mixtures; and it allows for every individual compound a straightforward evaluation of chem. integrity and structure-activity relation after biol. testing.The library size handled with this methodol. is more limited than in a pooling strategy.Pooled mixture formation is straightforward and less time-consuming than the synthesis of individual compoundsMore difficult is the anal. and screening of mixtures of components. By the split and mix technol., very large libraries can be formed progressively over multiple synthetic steps.

100 项与 Alantos Pharmaceuticals AG 相关的药物交易

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100 项与 Alantos Pharmaceuticals AG 相关的转化医学

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