Objective The study aimed to evaluate the effect of Salacia extract and naringin on blood glucose. Methods A randomized, double blind, placebo-controlled, parallel-group study was conducted in 60 healthy volunteers. The subjects were randomly divided into two groups and took placebo food or test food containing Salacia extract and naringin for 12 wk. The primary outcome was HbAlc and the secondary outcome was fasting blood glucose, insulin, HOMA-IR, 1,5-AG, body weight, BMI and triglycerides. Results The test food didn't suppress HbAlc significantly than placebo, but significantly increased 1.5-AG. Addnl., in the subgroup anal. with higher ΒΜΙ, the test food significantly suppressed HbAIc than placebo. ConcIusion These results suggest that the ingestion of Salacia extract and naringin suppresses HbAlc in healthy subjects with higher BML.