Karnataka Institute of Medical Sciences (Karnataka Institute of Medical Sciences)

概览

关联

25

项与 Karnataka Institute of Medical Sciences 相关的临床试验

CTRI/2024/08/072722 / Not yet recruiting临床2/3期IIT

Effect of dexmedetomidine and ketamine on bispectral index during induction with propofol: A randomised double blinded controlled study - NIL

开始日期2024-08-30

申办/合作机构

Karnataka Institute of Medical Sciences

CTRI/2024/07/070936 / Not yet recruitingN/AIIT

Usefullness of oxygen reserve index as an early warning for desaturation during rapid sequence induction : a cross sectional study

开始日期2024-07-30

申办/合作机构

Karnataka Institute of Medical Sciences

CTRI/2024/07/069784 / Not yet recruiting临床2/3期IIT

Comparative evaluation of preoperative virtual operating room tour vs meditation music in allaying preoperative anxiety A prospective openlabel randomized controlled endpoint blinding study. - Nil

开始日期2024-07-12

申办/合作机构

Karnataka Institute of Medical Sciences

100 项与 Karnataka Institute of Medical Sciences 相关的临床结果

登录后查看更多信息

0 项与 Karnataka Institute of Medical Sciences 相关的专利（医药）

登录后查看更多信息

728

项与 Karnataka Institute of Medical Sciences 相关的文献（医药）

2024-09-28·IP Journal of Surgery and Allied Sciences

Anterolateral thigh free flap surgery for medial malleoli fracture with extensive dorsal foot skin defect: A case report

作者: Mudgal, Chandrashekar V ; Prasad, Krishna ; Naik, Rajesh B

Severe foot deformities, especially those affecting the dorsum of the foot, can make it difficult to perform daily activities. For example, mild pain when walking can be felt on the dorsal aspect of the foot, and toe contractures can make it difficult to wear non supportive shoes. Reconstructive surgeons face a great deal of difficulty in providing a suitable flap in accordance with the "like for like" reconstructive principle. The best outcomes for reconstructing small- to medium-sized dorsal foot lesions have been reported using local flaps and pedicled flaps. Reconstruction of large dorsal foot deformities is, however, hardly studied. In this work, we report our experience reconstructing large dorsal foot lesions using the free anterolateral thigh (ALT) flap.

2024-09-28·Indian Journal of Orthopaedics Surgery

Severe acinetobacter necrotizing fascitis following open reduction and tension band wiring for patella fracture: A case report

作者: Pawar, Vinay ; Hosangadi, Adiveppa A ; Naik, Rajesh B ; Kammar, Sherashah F

Necrotizing fasciitis (NF) is a rare form of bacterial infection that leads to necrosis of the fascia, skin, subcutaneous tissues and vasculature surrounding them; high mortality rate and morbidity make it a major concern. Here, a young male of 27 years who was previously healthy, came to the Emergency department for motor vehicle accident. It was determined that he suffered a closed transverse fracture of the left patella for which he undergoes open reduction and Tension band wiring. Post operatively a patient started with clinical image of necrotizing fasciitis like erythema, tenderness, blisters, and skin necrosis. Microbiological examination of the cultures unraveled that Acinetobacter species sensitive to meropenem. The patient was taken to the operation room for the fasciotomy and subsequently debridement of the wound was done to deal with the sepsis. Split skin graft was harvested and then placed on the wound site to facilitate the healing. At six month follow-up, the wound had closed adequately with a perfect outcome. An early diagnosis and a timely surgical debridement, the use of targeted antibiotic therapy, and the practice of vigilant wound care are essential strategy needed to prevent the complications and to see the best recovery.

2024-09-01·Journal of Pharmaceutical and Biomedical Analysis

Serum Organophosphorus compound levels as a surrogate marker for severity assessment and management in Acute Organophosphorus Poisoning − A novel approach

Article

作者: H B, Nidish ; Kurjogi, Mahantesh M ; S, Veeresh ; Kaulgud, Ram S ; Vanti, Gulamnabi L

Organophosphorus (OP) compounds are the most extensively used pesticides' class worldwide; cause most self‑poisoning deaths especially in India. Thus, it is utmost important for early identification and aggressive management of OP poisoning from the clinical perspective to prevent serious complications by using sophisticated LC-MS/MS approach. This was a prospective study involving 103 patients of OP cases admitted to Karnataka Institute of Medical Sciences from June 2022 to May 2023, based on the inclusion and exclusion criteria patients were subjected to study. On admission, venous blood was collected from patient with Malathion and Profenofos OP poisoning history and subjected to serum biomarker and to LC-MS/MS analysis. Out of the 103 patients, 68 patients consumed Profenofos (66%) and 35 patients consumed Malathion (34%). Pseudocholinesterase levels among the of OP cases revealed that the 33 patients had mild toxicity, 40 patients had moderate toxicity and 30 patients had severe toxicity of OP poisoning. Subsequently LC-MS/MS analysis showed that the results obtained are not in correlation with indirect serum marker pseudocholinesterase levels. On the other side, LC-MS/MS results are in correlation with the clinical outcome of the patients with respect to morbidity and mortality. Thus, LC-MS/MS approach to assess the OP levels in patients could be used as potential diagnostic and prognostic marker for the absolute quantification of OP compounds compared to indirect OP levels estimation.

100 项与 Karnataka Institute of Medical Sciences 相关的药物交易

登录后查看更多信息

100 项与 Karnataka Institute of Medical Sciences 相关的转化医学

登录后查看更多信息