The goal of this observational study is to investigate the efficacy of percutaneous electrolysis compared with dry needling on pain sensations and multifidus muscle properties in subjects with low back pain. The main questions it aims to answer are:
The high-intensity and low-intensity percutaneous electrolysis may induce pressure pain threshold (PPT) changes in myofascial trigger points in the low back during the intervention compared with dry needling.
Percutaneous electrolysis interventions may reduce stiffness in the multifidus muscle during the intervention compared with dry needling.

开始日期2024-11-04

申办/合作机构

Wroclaw University of Environmental & Life Sciences

[+2]

NCT06642233 / Active, not recruitingN/AIIT

Relationships Among Cervical Functional Test in Patients With Unspecific Neck Pain: a Descriptive and Correlation Study

The goal of this clinical trials is to describe and correlate the posture, function and disability of the cervical spine in patients with unspecific neck pain. The research hypothesis is: In patients with unspecific neck pain, there is a significant correlation between posture, function and disability of the cervical spine. Participants will take part in functional tests and complete surveys and questionnaires.

开始日期2024-06-21

申办/合作机构

Wroclaw University of Environmental & Life Sciences

[+1]

NCT06493149 / RecruitingN/AIIT

Tensegrity Principle in Massage Therapy on Selected Anatomical Examples

The study design is a randomised, controlled, parallel, two-arm trial. The subjects are randomly assigned to one of the study groups: the intervention group or the control group. The study will analyze the applicability of the tensegrity principle in the massage therapy. The main aim of this study is to examine if the tensegrity principle can be used in massage therapy to increase the effectiveness of the intervention. Contractile and passive mechanical properties are assessed before and after the intervention.

开始日期2024-06-01

申办/合作机构

Wroclaw University of Environmental & Life Sciences

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2025-01-01·Journal of Ethnopharmacology

Antibacterial and therapeutic potential of historic deposits of silesian healing clay – terra sigillata Silesiaca

Article

作者: Badora, Krzysztof ; Waroszewski, Jarosław ; Proćków, Jarosław ; Gębarowska, Elżbieta ; Gałka, Bernard ; Budek, Karolina ; Gębarowski, Tomasz ; Spielvogel, Izabela

ETHNOPHARMACOLOGICAL RELEVANCEThe increasing evolution of pathogen resistance is a global problem that requires novel solutions. Recently, an increased interest in ethnomedicinal sources can be observed in the derivation of new medicines. The return to traditional medicinal formulations handed down for generations is being followed, but it is necessary to revise them again, taking into account the generally accepted research protocol.AIM OF THE STUDYWe aimed to evaluate the antimicrobial potential of historical deposits of Silesian healing clay (SHC), used in ethnomedicine against Gram-positive bacteria and to assess their biological activity using a primary dermal fibroblast line (NHDF) and a model monocyte line (THP1).MATERIALS AND METHODSInformation on medicinal clay deposits that occur in Silesia and are traditionally used in ethnomedicine or ancient medicine and known as terra sigillata Silesiaca or SHC, was selected on available source materials and old prints and maps from the archives of the Polish Geological Institute (Wrocław, Poland). Subsequently, their places of occurrence were identified and traced in the field by taking three deposits from the Silesia territory: Upper Silesia (D1), Opole Silesia (D2), and Lower Silesian (D3) Voivodeships for analysis. Their basic parameters and antimicrobial efficacy against pathogenic bacteria, Gram-positive streptococci and staphylococci, including methicillin-resistant strains, were examined. The study evaluated the effects of clays on growth and vitality using a primary dermal fibroblast line (NHDF) and a monocytic line (THP1). Studies were performed on a cell culture model to determine the effects on tissue regeneration (fibroblasts) and anti-inflammatory effects (monocytes). The study attempted to identify the mechanism of antimicrobial action, especially the textural characteristics and geochemical composition, as well as the environmental reaction (pH).RESULTSSHCs were classified into the following textural classes: clay loam (D1), clay (D2), and sand (D3). The tested deposits have antimicrobial properties that reduce the bacterial population (10⁴ CFU) compared to the control (10⁸ CFU). The antimicrobial effect depends on the type of clay and the species or strain of bacteria used. In-house studies clearly showed that Staphylococcus aureus Pcm 2054 and Staphylococcus epidermidis MRSE ATCC 2538 cells were completely adsorbed by clay minerals from clay D3.13. Furthermore, 10% leachates also showed an antimicrobial effect, as a reduction in bacterial populations was observed ranging from 91 to 100%. The results showed stimulation of fibroblast culture proliferation and inhibition of the growth of inflammatory cells (monocytes).CONCLUSIONSHCs tested have antimicrobial potential, in particular D2.7, D2.11, and D3.13. The D3.13 deposit had a bactericidal effect against the staphylococci tested. Aqueous solutions of clays also showed bacteriostatic effect. The results obtained in cell culture model tests indicate properties that modulate the healing process - stimulation of fibroblast growth (NHDF line) and inhibition of monocyte growth (THP1 line).

2024-12-31·Environmental Technology Reviews

Advancing wastewater treatment with Azolla filiculoides waste: a comprehensive review of adsorption applications

作者: Lal, Basant ; Igwegbe, Chinenye Adaobi ; Ghosh, Soumya ; Onyeaka, Helen ; Ahmadi, Shabnam ; Meskini, Maryam ; Hosseini-Bandegharaei, Ahmad ; Malloum, Alhadji ; Osagie, Christian ; Bornman, Charné ; Al-Najjar, Shahad Z. ; Al-Sharify, Zainab T. ; Benettayeb, Asmaa ; Ajala, Oluwaseun Jacob

Rapid urbanisation and industrialisation have led to severe environmental pollution from the accumulation of wastewater and poorly treated or untreated industrial wastes.Traditional waste treatment methods are often expensive and ineffective in fully removing contaminants.As a result, there is a growing interest in exploring natural and cost-effective treatment systems.One such potential solution is the use of the aquatic fern, Azolla filiculoides Lam which has shown promise as a readily available, free-floating biomass that can effectively adsorb and remove metal ions and other pollutants from water.This review paper delves into the untapped potential of A. filiculoides bio-adsorbent, as a highly effective and eco-friendly solution for removing organic and inorganic pollutants from wastewater.The review also identified future research opportunities and recognized existing limitations in our understanding of A. filiculoides for wastewater treatment.Various aspects of its efficiency, including equilibrium isotherm, kinetics, thermodn., desorption, and adsorbent reclamation, have been studied.The research highlights A. filiculoides′s impressive maximum sp. surface area of 484 m²/g, enabling it to adsorb a wide range of contaminants effectively.Among the studied adsorption models, Langmuir and pseudo-second-order models best described the adsorption phenomena on this bio-adsorbent.Thermodn. evaluations further confirm that its waste can be utilized to construct feasible and spontaneous adsorption systems for efficient pollutant removal.It shows great promise as a bio-adsorbent to mitigate the adverse environmental impacts of wastewater pollution promoting sustainable water management practices.Further research and application of A. filiculoides in wastewater treatment could lead to substantial environmental benefits.

2024-12-31·Journal of Natural Fibers

Cottonization of Decorticated and Degummed Flax Fiber - A Novel Approach to Improving the Quality of Flax Fiber and its Biomedical Applications

作者: Wróbel-Kwiatkowska, Magdalena ; Czuj, Tadeusz ; Wojtasik, Wioleta ; Zimniewska, Małgorzata ; Kostyn, Kamil ; Preisner, Marta ; Szopa, Jan

There is a growing demand for high-quality natural fibers, including flax fibers, which possess bioactive compounds with antioxidant, antibacterial, and anti-inflammatory properties.Traditional methods like dew retting are commonly used for flax fiber production, but alternative approaches are sought for enhanced fiber quality.This study presents a novel method involving cottonization to improve the quality of flax fibers obtained from low-quality decorticated fibers.The research evaluates the quality enhancement through various stages of the new method, comparing it with dew retting.Studies conducted on both transgenic (B14) and non-transgenic flax fibers revealed a decrease in fiber polymers and bioactive compounds after cottonization compared to dew retting.However, despite this reduction, the antioxidant potential of cottonized fibers increased significantly.Moreover, cottonized flax fibers exhibited high antimicrobial activity, particularly against Pseudomonas aeruginosa.Furthermore, extracts from both transgenic and non-transgenic cottonized flax fibers showed cytotoxic effects on hamster lung fibroblast cells, indicating potential future applications in cancer research.These findings highlight the potential of cottonization in enhancing the quality and bioactivity of flax fibers, paving the way for further exploration in various applications, including medical and textile industries.

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