Exiqon A/S

LONDON, Oct. 17, 2023 /PRNewswire/ -- Medical technology innovator, Oncotech Nordic AB, awarded CE marking in 2022 for its mobile health screening technology, Ophtascan™, will be distributed in Sri Lanka for the first time this autumn through a new partnership with the DiaPearl Group. In development since 2014, Ophtascan™ is a mobile in-real-time detection system for pre-cancerous plus all four stages of lung, cervical, breast, uterine and prostate cancers. The technology can also be used for detecting type 2 diabetes. Continue Reading From left: Andre Rafnsson, Bren Sambunathan and Jeevan Gnanam The mobile screening technology is used by doctors and patients in Central Africa, where there is huge demand for diabetes and cancer screening plus diagnostics. The Ophtascan™ technology is currently being used by Sigma Africa clinicians in the Central African Republic, Democratic Republic of Congo, Liberia and Tanzania. In addition, the AI-powered Ophtascan™ technology will be distributed in Europe through Medical Express Romania. Using the technology, clinicians can use their own smartphone devices to photograph the iris of their patients and upload images to the Oncotech server. The Oncotech AI diagnostic and machine learning system then sends the results back to the clinician in under a minute. The test is non-invasive, quick and requires minimal equipment, meaning that testing can take place in remote locations away from hospitals. Sri Lankan partnership Bren Sambunathan, Chairman and CEO of the DiaPearl Group, who is leading the distribution drive in Sri Lanka and broadly Asia said, "The medical technology within the Ophtascan™ technology will ultimately assist in alleviating the impact of type 2 diabetes and cancer within our society". "The early detection of these conditions typically presents the best outcomes for patients and the sophisticated technology within the Ophtascan™ technology has true transformative potential. We at the DiaPearl Group are thrilled to be the first business partners within Asia for this ground-breaking innovation that is destined to have a positive impact globally." In February 2022, final validation of Ophtascan™ was completed, following tests on over 2,000 oncology patients over a three-year period. The scanning precision success rate was over 95 per cent, and last year reached a 97 per cent precision scanning rate, as additional patients were assessed and data was validated on a daily basis. In addition, new research is underway for tests that will examine the early warning signs for colon, bladder, kidney, pancreas and stomach cancer. Oncotech Nordic AB CEO Andre Rafnsson concluded, "Sri Lanka is the third of what will be several new telemedicine and remote health diagnostic business partners. We are now in discussion with potential partners in North America and BRICS countries, with the ultimate aim being to license the Ophtascan™ technology globally. Ophtascan™ is the registered trademark of Oncotech Nordic AB. About Oncotech Nordic AB Oncotech works with internationally acclaimed oncologists and clinical researchers in the EMEA region. The Therapeutic R&D and focus is on diagnostics (mobile in-time cancer screening technology) and cancer treatment therapies. The fully funded business was set up in London, UK in 2020 with a Nordic operational subsidiary in 2021, headed by CEO Andre Rafnsson. Photo: Logo : SOURCE Oncotech Nordic AB

DUBLIN, June 22, 2023 /PRNewswire/ -- The "Global Cancer Vaccine Partnering Terms and Agreements 2010-2023" report has been added to ResearchAndMarkets.com's offering. The Global Cancer Vaccine Partnering Terms and Agreements 2010-2023 report provides comprehensive access to available deals and contract documents for over 350 cancer vaccine deals. Trends in cancer vaccine partnering deals Disclosed headlines, upfronts, milestones and royalties by stage of development Cancer vaccine partnering contract documents Top cancer vaccine deals by value This report provides details of the latest cancer vaccine agreements announced in the life sciences since 2010. The report takes the reader through a comprehensive review cancer vaccine deal trends, key players, top deal values, as well as deal financials, allowing the understanding of how, why and under what terms, companies are entering cancer vaccine partnering deals. The report presents financial deal term values for cancer vaccine deals, listing by headline value, upfront payments, milestone payments and royalties, enabling readers to analyse and benchmark the financial value of deals. The middle section of the report explores the leading dealmakers in the cancer vaccine partnering field; both the leading deal values and most active cancer vaccine dealmaker companies are reported allowing the reader to see who is succeeding in this dynamic dealmaking market. One of the key highlights of the report is that over 350 online deal records of actual cancer vaccine deals, as disclosed by the deal parties, are included towards the end of the report in a directory format - by company A-Z, stage of development, deal type, therapy focus, and technology type - that is easy to reference. Each deal record in the report links via Weblink to an online version of the deal. In addition, where available, records include contract documents as submitted to the Securities Exchange Commission by companies and their partners. Whilst many companies will be seeking details of the payment clauses, the devil is in the detail in terms of how payments are triggered - contract documents provide this insight where press releases and databases do not. The initial chapters of this report provide an orientation of cancer vaccine dealmaking. Chapter 1 provides an introduction to the report, whilst chapter 2 provides an overview of the trends in cancer vaccine dealmaking since 2010, including details of headline, upfront, milestone and royalty terms. Chapter 3 provides a review of the leading cancer vaccine deals since 2010. Deals are listed by headline value. Where the deal has an agreement contract published at the SEC a link provides online access to the contract. Chapter 4 provides a comprehensive listing of the top 25 most active companies in cancer vaccine dealmaking with a brief summary followed by a comprehensive listing of cancer vaccine deals announced by that company, as well as contract documents, where available. Chapter 5 provides a comprehensive and detailed review of cancer vaccine partnering deals signed and announced since Jan 2010, where a contract document is available in the public domain. Each deal title links via Weblink to an online version of the deal record and contract document, providing easy access to each contract document on demand. Chapter 6 provides a comprehensive and detailed review of cancer vaccine partnering deals signed and announced since Jan 2010. The chapter is organized by specific cancer vaccine technology type. Each deal title links via Weblink to an online version of the deal record and where available, the contract document, providing easy access to each deal on demand. A comprehensive series of appendices is provided organized by cancer vaccine partnering company A-Z, stage of development, deal type, and therapy focus. Each deal title links via Weblink to an online version of the deal record and where available, the contract document, providing easy access to each deal on demand. The report also includes numerous tables and figures that illustrate the trends and activities in cancer vaccine partnering and dealmaking since 2010. In conclusion, this report provides everything a prospective dealmaker needs to know about partnering in the research, development and commercialization of cancer vaccine technologies and products. Key benefits In-depth understanding of cancer vaccine deal trends since 2010 Access to headline, upfront, milestone and royalty data Detailed access to actual cancer vaccine contracts entered into by leading biopharma companies Identify most active cancer vaccine dealmakers since 2010 Insight into terms included in a cancer vaccine partnering agreement, with real world examples Understand the key deal terms companies have agreed in previous deals Undertake due diligence to assess suitability of your proposed deal terms for partner companies In Global Cancer Vaccine Partnering Terms and Agreements 2010-2023, the available deals are listed by: Company A-Z Headline value Stage of development at signing Deal component type Specific therapy target Technology type Analyzing actual contract agreements allows assessment of the following: What are the precise rights granted or optioned? What is actually granted by the agreement to the partner company? What exclusivity is granted? What is the payment structure for the deal? How are sale sand payments audited? What is the deal term? How are the key terms of the agreement defined? How are IPRs handled and owned? Who is responsible for commercialization? Who is responsible for development, supply, and manufacture? How is confidentiality and publication managed? How are disputes to be resolved? Under what conditions can the deal be terminated? What happens when there is a change of ownership? What sublicensing and subcontracting provisions have been agreed? Which boilerplate clauses does the company insist upon? Which boilerplate clauses appear to differ from partner to partner or deal type to deal type? Which jurisdiction does the company insist upon for agreement law? Companies Mentioned 2A 3D Medicines A*STAR Bioprocessing Technology Institute Aura Biosciences Averion AV Therapeutics Beth Israel Deaconess Medical Center BGI CureLab Oncology CureVac Cyplasin Biomedical CYTLIMIC Daiichi Sankyo Dainippon Sumitomo Pharma Dalton Pharma Services Exiqon ExpreS2ion Biotechnologies Federal Ministry of Education and Research (BMBF) Flaskworks Georgia Health Sciences University GeoVax German Cancer Research Center Hookipa Pharma Human Vaccines Project iBio Icahn School of Medicine at Mount Sinai Ichor Medical Systems Leukaemia & Lymphoma Research LG Life Sciences Ligand Pharmaceuticals Massachusetts Life Sciences Center Mayo Clinic National Research Council Canada National Surgical Adjuvant Breast and Bowel Project OncoQR OncoSec Medical Oncotherapy Science PsiOxus Therapeutics Pulmotec PX Biosolutions Qiagen Radboud University Nijmegen Medical Centre Selecta Biosciences Selexis Sellas Clinicals Holding Seres Therapeutics Telormedix Teva Pharmaceutical Industries VGX International Vinnova ViroMed Vivalis VLP Therapeutics VLST Corporation Y-mAbs Therapeutics Yale University Yamaguchi University For more information about this report visit About ResearchAndMarkets.com ResearchAndMarkets.com is the world's leading source for international market research reports and market data. We provide you with the latest data on international and regional markets, key industries, the top companies, new products and the latest trends. Contact: Research and Markets Laura Wood, Senior Manager [email protected] For E.S.T Office Hours Call +1-917-300-0470 For U.S./CAN Toll Free Call +1-800-526-8630 For GMT Office Hours Call +353-1-416-8900 U.S. Fax: 646-607-1907 Fax (outside U.S.): +353-1-481-1716 Logo: SOURCE Research and Markets

LONDON, Oct. 19, 2022 /PRNewswire/ -- Medical technology innovator Oncotech Nordic AB has been awarded CE marking for the mobile health screening app, Ophtascan™, which is currently being trialled by doctors and patients in Central Africa, where there is huge demand for cancer screening and diagnosis. The new screening app is being used by Sigma Africa clinicians in the Central African Republic, Democratic Republic of Congo, Liberia and Tanzania. Continue Reading The Ophtascan™ app is used by clinicians from Sigma Africa in four countries. The Ophtascan™ mobile phone app works by a clinician taking a high resolution photographic image of the patient's eyes, which is then analysed by Oncotech Nordic AB, making use of thousands of data sets. The test is non-invasive, quick and requires minimal equipment, meaning that testing can take place in remote locations, far away from hospitals. Developed since 2014 by Oncotech Nordic AB, Ophtascan™ is a mobile in-real-time detection system of pre-cancerous and all four levels of cancer conditions and targeted oncological diseases. Clinicians can use their own smartphone devices, then photograph the iris of their patient, and upload the image to the Oncotech server. The Oncotech AI diagnostic and deep learning system then sends the results back to the clinician within just 25 seconds. Andre Rafnsson, CEO of Oncotech said, "We are delighted to be partnering with the UK charity MedAid, which provides essential healthcare to the underprivileged in remote villages in Africa. The charity has been operating for over 20 years, providing high quality, healthcare infrastructure and services, significantly improving the lives of those living in many communities across Africa." Simon Henry Opio-Emuna, CEO at MedAid added, "As we aim to improve health outcomes in Africa, we are excited to be working with Oncotech, who've provided us with training support on how to use the app. It's set to be a game-changer because it offers remote medical diagnosis at a very low cost per use, presenting excellent value to clinicians. It's easy to screen large numbers of patients and the test only takes a matter of seconds. Conditions currently clinically validated and screened include lung cancer, cervical cancer, breast cancer, uterine cancer and prostate cancer." Dr. John Paul Kaswija, a medical practitioner for Sigma Africa, a division of MedAid said, "Cancer survival rates are determined by a number of factors, and early detection is one of the most significant determinants. The diagnosis of cancer and type 2 diabetes can often be difficult because current healthcare systems require visits to hospitals, which is impractical for people in remote locations. In addition, most patients seek medical care when the disease is already advanced. The innovative Ophtascan™ app allows clinicians with a smartphone to quickly and precisely screen patients for pre-cancerous conditions, in real-time. A bonus is that it does not unnecessarily overload the public health care diagnostic system, hence eliminating patient cancer screening waiting lists." With its base of operations in both Sweden and the United Kingdom, Oncotech has been established by Andre Rafnsson, alongside a management team consisting of CTO Marat Kalimulov, CSO Professor Shamil Gantzev and COO Rustem Amirov. The roots of the Ophtascan™ proof of concept technology can be traced back to post-war research and rests on ancient technology. Until recently, technology was not sophisticated enough to realise the system's full potential. In 2014, Kalimulov and Professor Gantzev relaunched the initiative by incorporating IT and AI, giving fresh impetus to the possibilities offered by an examination of the eye. In 2022, final validation of Ophtascan™ was completed, following tests on 13,500 oncology patients over a three-year period. The scanning precision success rate was over 95 per cent, and last year reached a 97 per cent precision scanning rate, as additional patients were tested and data is validated on a daily basis. Andre Rafnsson concluded, "MedAid is the first of what will be several telemedicine and remote health diagnostic business partners in Africa, Europe, North America and Asia with the ultimate aim being to license the Ophtascan™ technology. In addition, new research is underway for Ophtascan™ tests that will examine the early warning signs for type 2 diabetes, a condition with rates that are seen as a 'ticking healthcare time-bomb'." Ophtascan™ is the registered trademark of Oncotech Nordic AB. About Oncotech Nordic AB Oncotech works with internationally acclaimed oncologists and clinical researchers in the EMEA region. The Therapeutic R&D and focus is on Diagnostics (mobile in-time cancer screening technology) and cancer treatment Therapies (breast, uterus, lung, prostate, pancreas, liver and neuroblastoma). R&D partners include: Dana Genetics A/S, Eldon Biologicals A/S, Cencor Technology Ltd, and My Blue Label APS. The fully funded business was set up in London, UK in 2020 with a Nordic operational subsidiary in 2021, headed by CEO Andre Rafnsson. Photo: Logo: SOURCE Oncotech Nordic AB