Delving into the Latest Updates on Mahasarakham University with Synapse

概览

关联

23

项与 Mahasarakham University 相关的临床试验

TCTR20221117001 / Not yet recruiting临床3期IIT

A randomized controlled trial evaluating virologic and renal outcomes after switching from TDF/FTC/EFV to TDF/3TC/DTG (TLD) versus DTG/3TC in virologically suppressed Thai PWH

开始日期2023-01-01

申办/合作机构

Mahasarakham University

TCTR20231102007 / Completed临床1/2期IIT

Outcomes of multidisciplinary team for epilepsy management at Setthathirat hospital in LAO PDR.

开始日期2021-11-10

申办/合作机构

Mahasarakham University

TCTR20210213003 / Completed临床1期IIT

Effectiveness of a school-based pregnancy prevention program on sexual health literacy, pregnancy prevention behavior and sexual risk behavior among female teenagers and their boyfriends: A randomized controlled trial

开始日期2021-07-01

申办/合作机构

Mahasarakham University

100 项与 Mahasarakham University 相关的临床结果

登录后查看更多信息

0 项与 Mahasarakham University 相关的专利（医药）

登录后查看更多信息

4,223

项与 Mahasarakham University 相关的文献（医药）

2024-12-31·Journal of Systematic Palaeontology

Xianyuechelys yingliangi : a new nanhsiungchelyid turtle from the Late Cretaceous of Ganzhou Basin, China

作者: Tong, Haiyan ; Han, Fenglu ; Ke, Yuzheng ; Niu, Kecheng ; Hu, Jinfeng ; Rummy, Paul

2024-12-01·Journal of Molecular Graphics and Modelling

Oxoanion complexation of nitroisophthalamide receptors: Insights from the DFT calculations

Article

作者: Wanno, Banchob ; Tabtimsai, Chanukorn ; Somtua, Thanawat ; Rakrai, Wandee

Amide derivative receptors have been designed to investigate the oxoanion complexation ability via hydrogen and halogen bond interactions. Structural, energetic and electronic properties of nitroisophthalamide receptors, i.e., di(benzyl)- (R1), di(hexafluoro)- (R2), di(chloro-,tetrafluoro)- (R3), di(hexachloro)-(R4), di(fluoro-,tetrachloro)-nitroisophthalamide (R5), and their complexes with C₂H₃O₂^-, C₇H₅O₂^-, NO₃^-, H₂PO₄^-, and ClO₄^- oxoanions were computed and obtained using the density functional theory calculations at the B3LYP/6-31G(d,p) theoretical level in gas phase. According to the computed results, all of oxoanions can form the stable complexes with amide receptors R1-R5 via exothermic process in which receptor R1 is found to interact with oxoanions through hydrogen bonds whereas the receptors R2-R5 are found to interact with oxoanion through both of hydrogen and halogen bonds. It is clearly seen that acetate ion displays the strongest complexation interaction with all receptors compared to the other oxoanions. In addition, electronic properties of receptors R1-R5 in both gas and DMSO phases are modified after complexation with oxoanions. Therefore, the designed amide receptors may be potentially used for oxoanion sensing application.

2024-12-01·Natural Products and Bioprospecting

Antiproliferative polyketides from fungus Xylaria cf. Longipes SWUF08-81 in different culture media

Article

作者: Noppawan, Pakin ; Churat, Audomsak ; Mongkolthanaruk, Wiyada ; McCloskey, Sirirath ; Suwannasai, Nuttika ; Senawong, Thanaset ; Tontapha, Sarawut ; Sawadsitang, Sasiphimol ; Moontragoon, Pairot ; Amornkitbamrung, Vittaya ; Jantaharn, Phongphan ; Sresuksai, Kittiwan

AbstractBioactive compounds from the wood-decay fungus Xylaria cf. longipes SWUF08-81, cultivated in three different culture media (GM, YM and PDB), were isolated. Their structures and stereochemistry were deduced from spectroscopic and MS data analysis, together with quantum chemical calculations of 13C NMR chemical shifts and electronic circular dichroism (ECD) spectra. Five undescribed polyketides including dibenzofuran (1), mellein (2), dihydroisocoumarin (15), and two pyrans (16, 17), together with twenty-three compounds were determined. Compounds 18 and 20 were significantly toxic against cancer cell lines (HCT116, HT29, MCF-7 and HeLa) based on the MTT assay. Quantification by HPLC showed that 18 was produced three-fold higher in the broth of PDB than YM. These studies showed that the production of different compounds were primarily dependent on nutrition sources and it has given a starting point for the growth optimization conditions for the scaling up of bioactive compounds production.Graphical Abstract

100 项与 Mahasarakham University 相关的药物交易

登录后查看更多信息

100 项与 Mahasarakham University 相关的转化医学

登录后查看更多信息