Indira Gandhi Institute of Medical Sciences (Indira Gandhi Institute of Medical Sciences)

概览

关联

125

项与 Indira Gandhi Institute of Medical Sciences 相关的临床试验

CTRI/2024/10/074892 / Not yet recruiting临床3期IIT

Early hydrocortisone in neonatal shock versus standard care,a randomized control trial - NIL

开始日期2024-10-15

申办/合作机构

Indira Gandhi Institute of Medical Sciences

CTRI/2024/09/073794 / Not yet recruitingN/AIIT

Efficacy, Safety and Pill burden of Sucroferric oxyhydroxide compared with Sevelamer carbonate in Indian dialysis patients with hyperphosphataemia: A randomized, active-controlled study - NIL

开始日期2024-10-01

申办/合作机构

Indira Gandhi Institute of Medical Sciences

CTRI/2024/08/072768 / Not yet recruiting临床3期IIT

Efficacy and Safety of Metformin compared to Watchful observation in Breast fibroadenoma- A randomized, controlled, assessor-blinded study from India - NILL

开始日期2024-09-01

申办/合作机构

Indira Gandhi Institute of Medical Sciences

[+1]

100 项与 Indira Gandhi Institute of Medical Sciences 相关的临床结果

登录后查看更多信息

0 项与 Indira Gandhi Institute of Medical Sciences 相关的专利（医药）

登录后查看更多信息

944

项与 Indira Gandhi Institute of Medical Sciences 相关的文献（医药）

2024-12-01·Journal of Trace Elements in Medicine and Biology

Impact of fluorosis on molecular predictors in pathogenesis of type 2 diabetes associated microvascular complications

Review

作者: Pal, Biplab ; Meenakshi, Sarasa ; Murti, Krishna ; Prakash, Ved ; Narapaka, Pavan Kumar ; Dhingra, Sameer ; Kumar, Nitesh ; Bahekar, Triveni

AIMThis review presents specific insights on the molecular underpinnings of the connection between fluorosis, type 2 diabetes, and microvascular complications, along with the novel biomarkers that are available for early detection.SUMMARYFluoride is an essential trace element for the mineralization of teeth and bones in humans. Exposure to higher concentrations of fluoride has harmful effects that significantly outweigh its advantageous ones. Dental fluorosis and skeletal fluorosis are the common side effects of exposure to fluoride, which affect millions of individuals globally. Alongside, it also causes non-skeletal fluorosis, which affects the population suffering from non-communicable diseases like diabetes by impacting the soft tissues and causing diabetic microvascular complications. Previous studies reported the prevalence range of these diabetic complications of neuropathy (3-65 %), nephropathy (1-63 %), and retinopathy (2-33 %). Fluoride contributes to the development of these complications by causing oxidative stress, cellular damage, degrading the functioning capability of mitochondria, and thickening the retinal vein basement.CONCLUSIONEarly diagnosis is a prompt way of prevention, and for that, biomarkers have emerged as an innovative and useful technique. This allows healthcare practitioners and policymakers in endemic areas to comprehend the molecular complexities involved in the advancement of diabetic microvascular problems in the context of high fluoride exposure.

2024-09-10·Monaldi archives for chest disease = Archivio Monaldi per le malattie del torace

Infective pulmonary diseases and the eye: a narrative review.

Article

作者: Sinha, Bibhuti Prassan ; Katoch, Cds ; Doshi, Jinish ; Deokar, Kunal ; Singh, Mamta

Several infectious pulmonary diseases affect the eye. An understanding of the association between infectious pulmonary and ocular diseases is pivotal to their successful management. We aimed to review the infections affecting both the lungs and the eye. The electronic database PubMed and the search engine Google Scholar were searched for relevant articles. Ocular tuberculosis (TB), usually not associated with clinical evidence of pulmonary TB, can affect almost all the ocular structures. Confirmation of the diagnosis of ocular TB requires demonstration of Mycobacterium tuberculosis in ocular fluids/tissues. Among the drugs used to treat TB, ethambutol, isoniazid, and linezolid may cause toxic optic neuropathy. Elderly, those with renal disease, diabetes mellitus, malnourished, alcoholics, and those who will receive ethambutol at doses greater than 15 mg/kg/day and for prolonged periods are at high risk of developing toxic optic neuropathy. These individuals should be referred to an ophthalmologist before initiating ATT for a baseline ophthalmic evaluation. Linezolid may also cause toxic retinal neuropathy. Rifampicin may cause yellowish-orange discoloration of tears and contact lenses. Adenovirus, coronavirus, influenza virus, respiratory syncytial virus, and rhinovirus exhibit both pulmonary and ocular tropism. Pneumocystis jirovecii choroiditis is rare and mainly seen when aerosolized pentamidine is used for pneumocystis pneumonia prophylaxis. Further research is needed to develop non-interventional strategies to diagnose ocular TB. Biomarkers for early detection of toxic optic neuropathy are a need of the hour. Genetic factors and mechanisms behind the development of ethambutol, isoniazid, and linezolid-induced toxic optic neuropathy need further study.

2024-09-01·Journal of Indian Association of Pediatric Surgeons

Epignathus with Cervical Lymphangioma

作者: Lal, Rohit ; Thakur, Vinit Kumar

ABSTRACTThe occurrence of teratoma is 1 in 4,000 live births. Head-and-neck region teratoma (epignathus) is rare. These patients present with facial disfigurement, respiratory problems, and difficulty in feeding. It warrants early excision to avoid any morbidity or mortality due to airway obstruction. We describe the management of a patient with pedunculated epignathus with cervical lymphangioma.

100 项与 Indira Gandhi Institute of Medical Sciences 相关的药物交易

登录后查看更多信息

100 项与 Indira Gandhi Institute of Medical Sciences 相关的转化医学

登录后查看更多信息