更新于:2025-01-23

SPIB

基本信息

别名
SPI-B、Spi-B transcription factor、SPIB
+ [1]
简介
Sequence specific transcriptional activator which binds to the PU-box, a purine-rich DNA sequence (5'-GAGGAA-3') that can act as a lymphoid-specific enhancer. Promotes development of plasmacytoid dendritic cells (pDCs), also known as type 2 DC precursors (pre-DC2) or natural interferon (IFN)-producing cells. These cells have the capacity to produce large amounts of interferon and block viral replication. May be required for B-cell receptor (BCR) signaling, which is necessary for normal B-cell development and antigenic stimulation.

分析

对领域进行一次全面的分析。
对领域进行一次全面的分析。
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