更新于：2024-11-01

Aphakia, Postcataract

白内障后无晶状体

更新于：2024-11-01

基本信息

别名

Aphakia, Postcataract、Aphakias, Postcataract、Aphakic Eye, Postcataract

+ [12]

简介

Absence of the crystalline lens resulting from cataract extraction.

关联

透明质酸钠/硫酸软骨素钠

靶点-

作用机制-

在研机构

Seikagaku Corp. [+1]

原研机构

Alcon Japan Ltd.

在研适应症

白内障后无晶状体 [+1]

非在研适应症-

最高研发阶段批准上市

首次获批国家/地区

日本

首次获批日期2009-08-20

项与白内障后无晶状体相关的临床试验

NCT06363448 / RecruitingN/AIIT

Yamani Technique Versus Proline Mesh for Intraocular Lens Scleral Fixation in Aphakia

The study aims to describe a new method of sulcus fixation of intraocular lenses (IOLs) using a prolene mesh and to compare its outcomes with Yamani technique.

开始日期2024-01-01

申办/合作机构

Sohag University

NCT05821101 / RecruitingN/AIIT

Clinical Outcomes of Clareon Vivity Intraocular Lens With Mini-Monovision Approach

Purpose is to study the clinical outcomes of Clareon Vivity and Clareon Vivity Toric intraocular lens (IOL) implants in patients who are planning to have cataract surgery in both eyes with a mini-monovision approach.

开始日期2023-04-06

申办/合作机构

Palo Alto Foundation Medical Group

[+1]

NCT04176965 / Active, not recruitingN/A

Clinical Investigation of the Safety and Effectiveness of FINEVISION HP Trifocal IOL

This study is a prospective, multicenter, randomized, double masked confirmatory trial comparing an investigational trifocal intraocular lens (IOL) and a commercially available monofocal IOL.

开始日期2022-05-30

申办/合作机构

Beaver-Visitec International, Inc.

100 项与白内障后无晶状体相关的临床结果

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100 项与白内障后无晶状体相关的转化医学

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0 项与白内障后无晶状体相关的专利（医药）

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项与白内障后无晶状体相关的文献（医药）

2021-12-20·Journal of Ophthalmology4区 · 医学

Scleral Fixation of Akreos AO60 Intraocular Lens Using Gore-Tex Suture: An Eye on Visual Outcomes and Postoperative Complications

4区 · 医学

ArticleOA

作者: Leuzinger-Dias, Mariana ; Fernandes, Vítor ; Madeira, Carolina ; Rodrigues, Rita ; Oliveira-Ferreira, Cláudia ; Falcão, Manuel ; Lima-Fontes, Mário ; Falcão-Reis, Fernando ; Rocha-Sousa, Amândio

Purpose. “In-the-bag” placement of an IOL is the Holy Grail for any cataract surgeon. However, in the absence of capsular integrity, alternative surgical options to place the IOL must be sought. We aim to report the clinical outcomes and safety profile of scleral-fixated Akreos AO60 intraocular lens implantation using Gore-Tex suture, combined with pars plana vitrectomy. Methods. This is a single-center, retrospective case series descriptive study. Electronic clinical records of all patients subjected to scleral fixation of a Bausch and Lomb Akreos AO60 IOL combined with pars plana vitrectomy, between April 1, 2017, and August 1, 2021, were reviewed. Data concerning age, sex, laterality, past ophthalmological history, pre- and postoperative best-available visual acuity, surgical indication, and intra- and postoperative complications were collected. Measured outcomes were the differences in best-available visual acuity and frequency of postoperative complications. Results. A total of 37 eyes (20 right eyes and 17 left eyes) from 36 patients (16 females and 20 males) were included in the statistical analysis. The mean age at time of surgery was 72.0 ± 12.4 years. The mean follow-up period was 548.9 days (range 39–1564 days). Globally, the mean best-available logMAR visual acuity improved from 1.61 preoperatively (0.025 decimal equivalent) to 0.57 postoperatively (0.3 decimal equivalent), this difference being statistically significant (

P < 0.001

). Indications for surgery included aphakia due to complicated cataract surgery (24.3%; n = 9); subluxated IOL due to closed trauma (21.6%; n = 8); PEX-related subluxated IOL (16.2%; n = 6); non-traumatic, non-PEX-related subluxated IOL (18.9%; n = 7); subluxated crystalline lens due to closed trauma (8.1%; n = 3); aphakia due to open-globe injury (5.4%; n = 2); silicone-induced IOL opacification (2.7%; n = 1); and aphakia post-endophthalmitis (2.7%; n = 1). Postoperative complications included transient ocular hypertension (27.0%; n = 10), transient corneal edema (18.9%; n = 7), cystoid macular edema (18.9%, n = 7), self-limited hypotension (5.4%, n = 2), self-limited vitreous hemorrhage (2.7%, n = 1), central retinal vein occlusion (2.7%, n = 1), late retinal detachment (2.7%, n = 1), and Akreos IOL opacification (2.7%, n = 1). No suture-related complications were observed. Conclusion. There was a statistically significant improvement in visual acuity after scleral fixation of Akreos AO60 intraocular lens using Gore-Tex suture, with no suture-related problems recorded. This procedure seems to be a valuable alternative for posterior chamber IOL placement when secondary IOL implantation is required.

2020-03-01·Der Ophthalmologe4区 · 医学

Operationszeitpunkt der kongenitalen Katarakt

4区 · 医学

Review

作者: Kuhli-Hattenbach, C ; Kohnen, T ; Fronius, M

A congenital cataract is a rare disorder, which is associated with a high risk of amblyopia. Ophthalmologists are faced with many diagnostic and surgical challenges in the management of this disease. Older children can undergo primary treatment with an intraocular lens, whereas children younger than 12 months of age usually initially remain aphakic. The most frequent long-term complication of aphakic eyes following congenital cataract surgery in connection with posterior capsulorrhexis and anterior vitrectomy is aphakic glaucoma, which in individual cases can lead to substantial impairment of vision. Many factors have been reported to increase the risk of postoperative glaucoma, including microphthalmos, fetal nuclear cataract, conspicuous family history and associated ocular malformations, such as persistent fetal vasculature (PFV). Cataract surgery during early infancy is well-established to be the most important factor for the formation of postoperative aphakic glaucoma. In individual treatment planning it has to be considered that although younger age at the time of cataract removal can provide better prerequisites for prophylaxis of amblyopia, it also confers a higher risk of development of aphakic glaucoma. Children undergoing congenital cataract surgery have to be regularly monitored given the lifelong risk for postoperative complications, such as aphakic glaucoma.

2020-01-01·GMS ophthalmology cases

A technique for the management of posttraumatic aniridia and aphakia.

作者: Costa Andrade, Gabriel ; Pereira Bruxelas, Carolina ; Correa Maia, André ; Sousa Silva, Rita

Aim: To describe our results with HumanOptics IOL-ArtificialIris complex in post traumatic aphakia and aniridia. Methods: Retrospective, single-surgeon chart review of cases in which aniridia and aphakia were corrected using HumanOptics IOL-ArtificialIris complex sutured to the sclera with Gore-Tex^® sutures and coupled with the Akreos^® IOL (Bausch&Lomb). Results: The authors present four cases of ocular trauma with globe rupture. For every patient, posterior vitrectomy was done and an artificial iris-lens diaphragm was sutured to the sclera. All patients had a good functional and cosmetic outcome. Conclusions: Surgical implantation of the HumanOptics IOL-ArtificialIris complex coupled with the Akreos^® IOL was successful in alleviating post-trauma aphakia and aniridia related visual impairment.