OnabotulinumtoxinA (VA Office of Research and Development)

If approved, BOTOX® Cosmetic (onabotulinumtoxinA) would be the only neurotoxin with five aesthetic indications and the first and only approved for masseter muscle prominence in the U.S. Submission is supported by two Phase 3 studies (M21-416 and M21-417), demonstrating statistically significant improvements in masseter muscle prominence and patient satisfaction with treatment IRVINE, Calif., Aug. 4, 2026 /PRNewswire/ -- Allergan Aesthetics, an AbbVie company (NYSE: ABBV), today announced the U.S. Food and Drug Administration (FDA) has accepted for review its supplemental Biologics License Application (sBLA) for BOTOX® Cosmetic (onabotulinumtoxinA) for the temporary improvement in the appearance of marked to very marked masseter muscle prominence (MMP) associated with masseter muscle activity in adults. If approved, BOTOX® Cosmetic would become the first and only neurotoxin indicated for this condition in the U.S. and expand its portfolio to a fifth aesthetic indication. "This submission builds on the depth and versatility of BOTOX® Cosmetic and reflects our continued investment in advancing aesthetic medicine," said Darin Messina, Ph.D., senior vice president, head of aesthetics research and development, AbbVie. "At Allergan Aesthetics, our approach to innovation includes both developing new treatment options and continuing to expand the potential of established products. The pursuit of a fifth aesthetic indication demonstrates that commitment to addressing evolving patient needs." MMP can contribute to the appearance of a wider or more square lower face. This submission addresses a growing patient interest in non-surgical facial contouring options, offering a clinically studied approach to achieving improved jawline definition and shape, as well as a more slimming jawline overall. If approved, this indication would provide both patients and aesthetic specialists with a differentiated, science-backed treatment option. "Patients are increasingly seeking overall facial assessments with non-surgical options to address aesthetic needs for the lower face," said Steve Yoelin, MD, a coordinating clinical investigator with over 25 years of experience in minimally invasive medical aesthetics. "As facial assessment continues to evolve beyond individual treatment areas, this indication would further broaden the clinical utility of BOTOX® Cosmetic, if approved, by providing an important new treatment option." The sBLA submission is supported by two Phase 3 clinical studies (M21-416 and M21-417), both of which met their primary endpoints and demonstrated statistically significant improvements in the severity of masseter muscle prominence compared with placebo (p=0.0046 and p=0.0014, respectively). The safety profile was consistent with established uses, with no new safety signals identified. Patient satisfaction was also demonstrated, with twice as many patients treated with BOTOX® Cosmetic reporting they were "Very Satisfied" or "Satisfied" compared with placebo. BOTOX® Cosmetic (onabotulinumtoxinA) Important Information BOTOX® Cosmetic (onabotulinumtoxinA) is indicated in adult patients for the temporary improvement in the appearance of: - Moderate to severe glabellar lines associated with corrugator and/or procerus muscle activity - Moderate to severe lateral canthal lines associated with orbicularis oculi activity - Moderate to severe forehead lines associated with frontalis activity - Moderate to severe platysma bands associated with platysma muscle activity IMPORTANT SAFETY INFORMATION, INCLUDING BOXED WARNING CONTRAINDICATIONS BOTOX® Cosmetic is contraindicated in the presence of infection at the proposed injection site(s) and in individuals with known hypersensitivity to any botulinum toxin preparation or to any of the components in the formulation. WARNINGS AND PRECAUTIONS Lack of Equivalency Between Botulinum Toxin Products The potency Units of BOTOX ® Cosmetic are specific to the preparation and assay method utilized. BOTOX ® Cosmetic is not equivalent to other preparations of botulinum toxin products, and therefore, Units of biological activity of BOTOX ® Cosmetic cannot be compared to nor converted into Units of any other botulinum toxin products assessed with any other specific assay method. Spread of Toxin Effect Please refer to Boxed Warning for Distant Spread of Toxin Effect. No definitive serious adverse event reports of distant spread of toxin effect associated with dermatologic use of BOTOX® Cosmetic at the labeled dose of 20 Units (for glabellar lines), 24 Units (for lateral canthal lines), 40 Units (for forehead lines with glabellar lines), 44 Units (for simultaneous treatment of lateral canthal lines and glabellar lines), and 64 Units (for simultaneous treatment of lateral canthal lines, glabellar lines, and forehead lines) have been reported. Patients or caregivers should be advised to seek immediate medical care if swallowing, speech, or respiratory disorders occur. Serious Adverse Reactions With Unapproved Use Serious adverse reactions, including excessive weakness, dysphagia, and aspiration pneumonia, with some adverse reactions associated with fatal outcomes, have been reported in patients who received BOTOX® injections for unapproved uses. In these cases, the adverse reactions were not necessarily related to distant spread of toxin, but may have resulted from the administration of BOTOX® to the site of injection and/or adjacent structures. In several of the cases, patients had preexisting dysphagia or other significant disabilities. There is insufficient information to identify factors associated with an increased risk for adverse reactions associated with the unapproved uses of BOTOX®. The safety and effectiveness of BOTOX® for unapproved uses have not been established. Hypersensitivity Reactions Serious and/or immediate hypersensitivity reactions have been reported. These reactions include anaphylaxis, serum sickness, urticaria, soft-tissue edema, and dyspnea. If such a reaction occurs, discontinue further injection of BOTOX Cosmetic and immediately institute appropriate medical therapy. One fatal case of anaphylaxis has been reported in which lidocaine was used as the diluent and, consequently, the causal agent cannot be reliably determined. Cardiovascular System There have been reports following administration of BOTOX® of adverse events involving the cardiovascular system, including arrhythmia and myocardial infarction, some with fatal outcomes. Some of these patients had risk factors, including preexisting cardiovascular disease. Use caution when administering to patients with preexisting cardiovascular disease. Increased Risk of Clinically Significant Effects With Preexisting Neuromuscular Disorders Patients with neuromuscular disorders may be at increased risk of clinically significant effects, including generalized muscle weakness, diplopia, ptosis, dysphonia, dysarthria, severe dysphagia, and respiratory compromise from onabotulinumtoxinA (see Warnings and Precautions). Monitor individuals with peripheral motor neuropathic diseases, amyotrophic lateral sclerosis or neuromuscular junction disorders (eg, myasthenia gravis or Lambert-Eaton syndrome) when given botulinum toxin. Dysphagia and Breathing Difficulties Treatment with BOTOX® and other botulinum toxin products can result in swallowing or breathing difficulties. Patients with preexisting swallowing or breathing difficulties may be more susceptible to these complications. In most cases, this is a consequence of weakening of muscles in the area of injection that are involved in breathing or oropharyngeal muscles that control swallowing or breathing (see Boxed Warning). Preexisting Conditions at the Injection Site Use caution when BOTOX® Cosmetic treatment is used in the presence of inflammation at the proposed injection site(s) or when excessive weakness or atrophy is present in the target muscle(s). Dry Eye in Patients Treated With BOTOX ® Cosmetic There have been reports of dry eye associated with BOTOX® Cosmetic injection in or near the orbicularis oculi muscle. If symptoms of dry eye (eg, eye irritation, photophobia, or visual changes) persist, consider referring patients to an ophthalmologist. Human Albumin and Transmission of Viral Diseases This product contains albumin, a derivative of human blood. Based on effective donor screening and product manufacturing processes, it carries a remote risk for transmission of viral diseases and variant Creutzfeldt-Jakob disease (vCJD). There is a theoretical risk for transmission of Creutzfeldt-Jakob disease (CJD), which would also be considered remote. No cases of transmission of viral diseases, CJD, or vCJD have ever been identified for licensed albumin or albumin contained in other licensed products. ADVERSE REACTIONS The most frequently reported adverse reactions following injection of BOTOX® Cosmetic for glabellar lines were eyelid ptosis (3%), facial pain (1%), facial paresis (1%), and muscular weakness (1%). The most frequently reported adverse reaction following injection of BOTOX® Cosmetic for lateral canthal lines was eyelid edema (1%). The most frequently reported adverse reactions following injection of BOTOX® Cosmetic for forehead lines with glabellar lines were headache (9%), brow ptosis (2%), and eyelid ptosis (2%). The safety profile of BOTOX® Cosmetic treatment of platysma bands is consistent with the known safety profile of BOTOX® Cosmetic for other indications. DRUG INTERACTIONS Coadministration of BOTOX® Cosmetic and aminoglycosides or other agents interfering with neuromuscular transmission (eg, curare-like compounds) should only be performed with caution as the effect of the toxin may be potentiated. Use of anticholinergic drugs after administration of BOTOX® Cosmetic may potentiate systemic anticholinergic effects. The effect of administering different botulinum neurotoxin products at the same time or within several months of each other is unknown. Excessive neuromuscular weakness may be exacerbated by administration of another botulinum toxin prior to the resolution of the effects of a previously administered botulinum toxin. Excessive weakness may also be exaggerated by administration of a muscle relaxant before or after administration of BOTOX® Cosmetic. USE IN SPECIFIC POPULATIONS There are no studies or adequate data from postmarketing surveillance on the developmental risk associated with use of BOTOX® Cosmetic in pregnant women. There are no data on the presence of BOTOX® Cosmetic in human or animal milk, the effects on the breastfed child, or the effects on milk production. Please see BOTOX ® Cosmetic full Prescribing Information , including Boxed Warning and Medication Guide . About Allergan Aesthetics At Allergan Aesthetics, an AbbVie company, we develop, manufacture, and market a portfolio of leading aesthetics brands and products. Our aesthetics portfolio includes facial injectables, body contouring, plastics, skin care, and more. Our goal is to consistently provide our customers with innovation, education, exceptional service, and a commitment to excellence, all with a personal touch. For more information, visit . About AbbVie AbbVie's mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people's lives across several key therapeutic areas including immunology, neuroscience and oncology – and products and services in our Allergan Aesthetics portfolio. For more information about AbbVie, please visit us at . Follow @abbvie on LinkedIn, Facebook, Instagram, X and YouTube. Forward-Looking Statements Some statements in this news release are, or may be considered, forward-looking statements for purposes of the Private Securities Litigation Reform Act of 1995. The words "believe," "expect," "anticipate," "project" and similar expressions and uses of future or conditional verbs, generally identify forward-looking statements. AbbVie cautions that these forward-looking statements are subject to risks and uncertainties that may cause actual results to differ materially from those expressed or implied in the forward-looking statements. Such risks and uncertainties include, but are not limited to, challenges to intellectual property, competition from other products, difficulties inherent in the research and development process, adverse litigation or government action, changes to laws and regulations applicable to our industry, the impact of global macroeconomic factors, such as economic downturns or uncertainty, international conflict, trade disputes and tariffs, and other uncertainties and risks associated with global business operations. Additional information about the economic, competitive, governmental, technological and other factors that may affect AbbVie's operations is set forth in Item 1A, "Risk Factors," of AbbVie's 2025 Annual Report on Form 10-K, which has been filed with the Securities and Exchange Commission, as updated by its Quarterly Reports on Form 10-Q and in other documents that AbbVie subsequently files with the Securities and Exchange Commission that update, supplement or supersede such information. AbbVie undertakes no obligation, and specifically declines, to release publicly any revisions to forward-looking statements as a result of subsequent events or developments, except as required by law. SOURCE AbbVie 21% more press release views with Request a Demo

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Injection to Balance Eyebrows and Facial Shapes: A Review with Illustrative Clinical Examples 78.Three-dimensional three-interval thixotropy test (3D-3ITT) protocol for cosmetic lotions: A proof-of-concept study linking thixotropy to sensory and emotional responses 79.Bridging the gap between consumer perception and objective measurements: A novel multiview image analysis methodology for quantifying hair volume on a human head (curl type I to III) 80.Real-world evidence for the efficacy and tolerability of an isobutylamido-thiazolyl-resorcinol (Thiamidol)-containing skincare regimen on facial hyperpigmentation and overall skin appearance: A multi-centre study in 11 European countries 81.A Possible Role of Mycobiome in the Pathophysiology of Acne: Structured Narrative Review and Perspectives 82.MFAP4 Promotes Scar Formation by Regulating Macrophage-Myofibroblast Transformation Through Activation of the TGF-β/Smad3 Signalling Pathway 83.Polynucleotides and Polydeoxyribonucleotides for Skin Rejuvenation, Postoperative Scar Prevention, and Wound Healing: A Systematic Review of Randomized Clinical Trials 84.First Case Series on Ambulatorial Endoscopic Sleeve Gastroplasty for Morbidity Obesity: A Single Center Experience 85.Short-Term Clinical and Metabolic Outcomes of Laparoscopic Sleeve Gastrectomy in Korean Adolescents with Severe Obesity: A Retrospective Analysis 86.Neural Decision-Making and Affective Dynamics in Weight Regain after Metabolic and Bariatric Surgery: A Multimodal Longitudinal Computational Psychiatry Study 87.Beyond Initial Resolution: Predictors of Recurrence of Obesity-related Medical Conditions after Metabolic and Bariatric Surgery 88.Fractional CO2 Laser in Lichen Amyloidosis With Rapid Pruritus Resolution and Long-Term Remission: Serial PGP9.5 and Dylon Observations With Touch Sensitivity Assessment 89.Integrated single-cell and spatial transcriptomic analyses reveal an aging-associated fibroblast subtype linked to tumor progression in human skin 90.Microcore Skin Biopsies: A Novel, Micro-Invasive Skin Biopsy Technique Yielding Full-Thickness Histology 91.Topical Melatonin in Aesthetic Dermatology: From Cutaneous Melatoninergic Biology to Photoprotection, and Skin Rejuvenation 92.Fast-tracking dermatologic care for “VIP” patients: ethical concerns and practical approaches 93.Acneiform Eruption with Deucravacitinib: Systematic Review and Meta-Analysis 94.Topical Hypochlorous Acid for Acne Vulgaris: Mechanisms, Clinical Evidence, and Therapeutic Potential 95.Equity Evaluation: Analysis of the Prescribing Patterns of Isotretinoin Based on Reproductive Potential 96.Rosacea: We Still Haven’t Found What We’re Looking For 1. 鼻整形术对性生活活跃已婚女性性功能、自尊及抑郁症状的影响（更正） 2. 评《评估大语言模型生成医疗文书的效能：ChatGPT-4、ChatGPT-4o与Claude的比较研究》 3. 无脱细胞真皮基质及补片的胸前乳房重建：呼吁比较性证据 4. 皮内注射10%葡萄糖（Sihler G）用于头皮毛发再生：一项随机、评估者设盲的预试验研究 5. 肌内臀部填充的技术演进：15年队列、5081例手术及高级臀部塑形术（MAG）的创立 6. A型肉毒毒素注射后骨骼肌的细胞重塑：一项单核RNA测序研究 7. A型肉毒毒素：迷思、证据与全球媒体叙事 8. 激光、微针及联合疗法治疗中重度萎缩性痤疮瘢痕：一项系统综述与网状Meta分析 9. 肌肉作为眉间肉毒毒素注射的基本治疗单元：技术描述与初步临床经验 10. A型肉毒毒素通过抑制TGF-β1/Smad通路减轻兔耳模型增生性瘢痕形成（更正） 11. 致编辑的信回复：《肌内效贴作为外部机械疗法：将其作用从乳腺手术拓展至身体塑形》 12. 评《肋软骨切取的新理念以减轻供区术后疼痛》 13. 单瓣耳廓重建中的新型耳上切口：一项回顾性研究 14. 先天性单睑与重睑的睑板前纤维脂肪筋膜层：一项尸体、组织学及超声研究 15. 面部自体脂肪移植后脂肪坏死：已报道并发症及处理策略的系统综述 16. 血管紧张素Ⅱ作为烧伤后增生性瘢痕评估与预测的新型生物标志物：一项倾向评分匹配队列研究 17. 美容外科领域医患信任多维测量量表的构建方案 18. CO₂激光消融术与锥切术治疗宫颈上皮内瘤变2级：一项前瞻性队列研究 19. 点阵微针射频治疗光老化及萎缩性痤疮瘢痕：两种设备的半脸临床观察 20. 强脉冲光（IPL）、脉冲染料激光（PDL）与Q开关掺钕钇铝石榴石（Nd:YAG）激光治疗中重度炎症性痤疮的疗效与安全性比较：一项三臂随机对照临床试验 21. 保留皮肤清创联合负压滴注滞留伤口治疗早期坏死性筋膜炎 22. 90度叶旋转的岛状双叶皮瓣修复基底细胞癌切除后鼻尖缺损 23. 超微血管成像增强淋巴超声用于淋巴水肿相关淋巴管静脉吻合术前定位 24. 腹壁下深动脉穿支皮瓣乳房重建联合血管化淋巴结移植及腹壁整形的一体化显微外科康复 25. 背阔肌皮瓣治疗放射性胸壁溃疡 26. 神经源性胸廓出口减压术中采用再生性周围神经界面处理锁骨上神经横断 27. 照亮黑暗：吲哚青绿血管造影评估晚期动静脉环血栓后游离皮瓣自主血运重建 28. 负压伤口治疗调节铜绿假单胞菌感染猪伤口的pH值及细菌侵袭 29. DIEP皮瓣重建中双穿支的血流动力学优势 30. 解读至关重要：回顾性外科研究中的常见统计学陷阱 31. 为整形外科医生构建实用人工智能工具：Cowork分步指南 32. 患者对透明质酸填充剂的认知误区：基于经验的思考 33. 鼻整形术后镜像对峙困扰：患者报告结局测量工具的开发与验证 34. 稀释型羟基磷灰石钙羧甲基纤维素（Radiesse）治疗颈胸区皱纹：成年女性的安全性与有效性 35. 整形外科中的人工智能：100篇最高被引英文出版物的文献计量学与可视化分析 36. 乳房植入物及肋骨骨髓炎中的偶发分枝杆菌感染：一例病例报告及文献复习 37. 超稀释羟基磷灰石钙注射联合点阵微针射频改善膨胀纹：一项预试验研究 38. 一次手术、多根神经、多样疼痛表型：面部透明质酸注射后三叉神经病理性疼痛四例病例系列 39. 采用预修剪法的非剃发毛囊单位提取及大剂量毛发移植：巴西外科团队经验 40. 乳蛋白水解物对自觉皮肤暗沉女性皮肤质量及晚期糖基化终末产物的影响：两项为期8周的随机对照试验 41. 蜂蜜作为化妆品配方中保湿成分的功效：临床试验的系统综述 42. 面部美容外科中的光生物调节疗法：疗效与安全性的系统综述 43. 化学剥脱术在色素性皮肤病治疗中的应用进展 44. Q开关Nd:YAG激光去除艺术性及美容性纹身 45. 损伤病因与瘢痕结局的关联：一项回顾性临床研究 46. 上面部皱纹神经毒素注射时机 47. 大剂量多通道射频治疗对内脏及皮下腹部脂肪的影响：一项干预前后研究 48. 化妆品使用及其潜在风险：印度旁遮普地区公众认知与态度评估 49. 外用曲法罗汀治疗马来西亚寻常痤疮的疗效与耐受性：一项单臂、开放标签、观察性研究 50. 多核苷酸注射后面部双侧革兰阴性脓肿 51. 双平面生物刺激剂注射中的平面-厚度等分匹配探讨 52. 羟基磷灰石钙用于中国人群颞部轮廓修复的临床及三维评估 53. 采用尖端超声技术研究安全填充剂注射技术 54. 神经美学应用于美容医学的概念与披露考量 55. 植入物相关ASIA及乳房植入物疾病中的全身症状模式：一项研究水平描述性系统综述 56. 寻常痤疮中的睡眠-压力-皮肤轴 57. 采用高能量密度1064nm皮秒激光的统一黄金参数疗法无副作用去除纹身 58. 含补骨脂酚与水杨酸的护肤霜治疗轻中度寻常痤疮的疗效与安全性：一项非劣效性随机对照试验 59. 外用山椒素衍生制剂治疗黄褐斑的疗效与安全性：一项随机、双盲、安慰剂对照试验 60. 评射频微针与点阵二氧化碳激光治疗面部萎缩性痤疮瘢痕的疗效、恢复及色素安全性比较：一项前瞻性随机半脸试验 61. 证据合成中的人工智能：益处、局限及透明报告的重要性 62. 近红外血管定位引导浅表皮肤血管病变的操作处理 63. 儿科患者的中央离心性瘢痕性脱发：一项回顾性分析 64. 透明质酸、氨基酸与维生素的焕活复合物促进人体皮肤微循环 65. 90天护肤方案期间皮肤变化的仪器与患者报告评估：一项前瞻性单臂观察性研究 66. 澳大利亚人群BODY-Q模块常模数据及与北美、欧洲常模的比较 67. 便携式结构光三维容积测量用于乳房及皮瓣评估：技术验证与工作流程开发 68. 鼻唇沟皮瓣在鼻重建中的多样化应用：基于缺损的算法 69. 数字时代的患者教育：在线瘢痕疙瘩信息可读性、质量及可操作性评估 70. 脂溢性皮炎对健康相关生活质量的影响：一项质性分析 71. 硬斑病组织中聚集蛋白聚糖的表达：纤维化细胞外基质积聚的潜在促成因素 72. 亚洲患者异维A酸方案的疗效与安全性比较：一项系统综述与Meta分析 73. 采用在体反射式共聚焦显微镜表征不同瘢痕成熟阶段人体瘢痕组织中的胶原 74. 老年肥胖及2型糖尿病患者使用GLP-1受体激动剂的特殊考量 75. 频繁饮用含糖饮料与生物衰老加速相关：来自人群研究及肠道菌群分析的证据 76. 痉挛管理专科进修带来的高级肉毒神经毒素注射培训收益 77. IncobotulinumtoxinA注射平衡眉形与面型：附临床示例的综述 78. 化妆品乳液的三维三区间触变性测试（3D-3ITT）方案：触变性与感官及情绪反应关联的概念验证研究 79. 弥合消费者感知与客观测量之间的差距：一种量化人体头部发量的新型多视角图像分析方法（Ⅰ-Ⅲ型卷发） 80. 含异丁基酰胺基-噻唑基-间苯二酚（Thiamidol）护肤方案改善面部色素沉着及整体皮肤外观的真实世界证据：11个欧洲国家的多中心研究 81. 真菌组在痤疮病理生理学中的可能作用：结构化叙述综述与展望 82. MFAP4通过激活TGF-β/Smad3信号通路调控巨噬细胞-肌成纤维细胞转化促进瘢痕形成 83. 多核苷酸与聚脱氧核苷酸用于皮肤年轻化、术后瘢痕预防及伤口愈合：随机临床试验的系统综述 84. 门诊内镜下袖状胃成形术治疗病态肥胖的首批病例系列：单中心经验 85. 韩国重度肥胖青少年腹腔镜袖状胃切除术的短期临床与代谢结局：一项回顾性分析 86. 代谢与减重手术后体重反弹中的神经决策与情感动力学：一项多模态纵向计算精神病学研究 87. 超越初始缓解：代谢与减重手术后肥胖相关疾病复发的预测因素 88. 点阵CO₂激光治疗淀粉样变苔藓伴瘙痒快速缓解及长期缓解：PGP9.5与Dylon系列观察及触觉敏感性评估 89. 单细胞与空间转录组整合分析揭示与人体皮肤肿瘤进展相关的衰老相关成纤维细胞亚型 90. 微芯皮肤活检：一种可获取全层组织学的新型微创皮肤活检技术 91. 美容皮肤科中的外用褪黑素：从皮肤褪黑素能生物学到光防护及皮肤年轻化 92. "VIP"患者皮肤科快速通道诊疗：伦理考量与实践路径 93. 氘可来昔替尼所致痤疮样皮疹：系统综述与Meta分析 94. 外用次氯酸治疗寻常痤疮：机制、临床证据及治疗潜力 95. 公平性评估：基于生育潜力的异维A酸处方模式分析 96. 玫瑰痤疮：我们仍未找到真正的答案 文献求助 1.Preserving the Modiolus: Enhanced Functional and Aesthetic Restoration with the Modified Bernard-Webster Technique in Lip Reconstruction（暂无） 2.Real-Time Integration of Patient-Reported Outcomes in Breast Cancer Surgery: Feasibility of the BREAST-Q REACT（暂无） 3.Why Plastic Surgery Must Rethink Residency Capacity 4.Seeing Clearly, Working Comfortably: 3D Exoscopes in Cleft Surgery Ergonomics and Education（暂无） 5.Exploring the Role of Fascia Lata Suspension in Triple Nerve Transfer for Facial Reanimation: A Comparative Outcomes Study 6.Vertical Superior Epigastric Artery Perforator Flap for Autologous Breast Augmentation After Massive Weight Loss（暂无） 7.The Impact of Nontobacco Nicotine Dependence on Postoperative Complications in Reconstructive and Aesthetic Breast Surgery Procedures: A Multicenter Propensity-Score Matched Analysis.（暂无） 8.Simultaneous 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Ritlecitinib治疗青少年重度斑秃的真实世界疗效与安全性：为期36周单中心研究 52. 富血小板血浆外用保湿制剂改善肤质效果的初步探究 53. 手术切口术后减张贴敷的美容预后效果：系统综述 54. 头颈部游离皮瓣术后铜绿假单胞菌感染的防治方案：系统综述与系列病例分析 55. 儿童鼻中隔鼻成形术：基于儿童健康信息系统数据库的队列研究 56. 依托标志点形态测量法实现鼻部发育三维预测：预测算法临床验证 57. 真皮基质材料定义标准：全球外科重建领域德尔菲专家共识研究结果 58. 假体置入式乳房整形术中人工合成补片与生物补片的组织反应：6例组织形态学系列病例研究 59. 乳房缩小术后乳头乳晕复合体感觉功能评估与研究现状：范围综述 60. 通讯论述：自体乳房重建术中成品化三维打印植入材料的应用规范 61. 琼脂水凝胶浓度依赖性非线性流变特性 62. 纤维蛋白基生物材料在创面愈合与软组织修复中的作用机制及临床应用 63. 从细胞外基质衰老到力学生物学修复：注射填充剂与真皮成纤维细胞力传导机制综述 64. 远距离非接触式皮肤镜：技术原理、临床应用与发展前景 65. 成纤维细胞状态重塑与基质耗竭调控人类阴茎皮肤衰老微环境 66. 2013-2023年白癜风治疗随机对照试验研究综述 67. 异维A酸常规实验室监测手段停用的必要性探讨 68. 生成式人工智能在皮肤科领域的双刃剑效应：医师职业倦怠、患者满意度及医患沟通质量的多维度横断面研究 69. 成年后痤疮全球疾病负担：1990至2021年25-49岁人群发病趋势分析 70. 磷脂酰胆碱类溶脂溶液皮下注射疗法引发迟发性过敏反应 71. 继发于淋巴水肿的上肢经典型卡波西肉瘤经Nd:YAG激光成功治愈 72. 透明质酸酶注射紧急救治氯化钙外渗损伤 73. 斑秃诊疗S3指南——第一部分：诊断与流行病学 74. 玫瑰痤疮皮肤炎症生物标志物及其与病情严重程度的相关性 75. 面向青年群体的防晒科普社交媒体活动降低皮肤癌风险的前后效果评估 76. 无假体置入前提下利用Liacyr蒂瓣实施对侧乳房肿瘤整形重建术 77. 背阔肌胸外侧皮瓣：全新全自体乳房重建术式 78. 双侧臀上动脉穿支皮瓣用于重度化脓性汗腺炎术后全臀重建 79. 乳房重建术中脂肪移植的超声影像学分析 80. 低成本仿真模型在脂肪抽吸术教学模拟训练中的应用 81. 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