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更新于：2026-07-18
OnabotulinumtoxinA (VA Office of Research and Development)
更新于：2026-07-18
概要
基本信息
在研机构- |
权益机构- |
最高研发阶段无进展临床2期 |
首次获批日期- |
最高研发阶段(中国)- |
特殊审评- |
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关联
4
项与 OnabotulinumtoxinA (VA Office of Research and Development) 相关的临床试验TCTR20220112005
Low-dose onabotulinumtoxinA using 7-point pattern intradermal axillary injections in patients with moderate-to-severe primary axillary hyperhidrosis
开始日期2022-01-17 |
申办/合作机构- |
ACTRN12614000196640
Evaluation of the efficacy of intradermal onabotulinumtoxinA for the treatment of accordion wrinkles: A 2-centre randomized double-blinded split face clinical trial
开始日期2014-02-24 |
申办/合作机构- |
NCT01589263
Effectiveness of OnabotulinumtoxinA (onaBoNT-A) vs Oral Tamsulosin in Men With Benign Prostatic Hyperplasia & Lower Urinary Track Symptoms (#02-10-10-05)
Benign prostatic hyperplasia (BPH) and its related symptoms are a common condition that affects nearly half of men over age 50 and 90% of men over 80. Lower urinary tract symptoms (LUTS) caused by BPH can be very troublesome, affect an individual's quality of life significantly, and are costly.
his Phase 2 clinical research trial is a double-blind, randomized, placebo-controlled, parallel-group study to compare the treatment effects of onaBoNT-A 200 U versus 0.4 mg per day of oral tamsulosin in male Veterans diagnosed with moderate to severe LUTS [American Urologic Association Symptom Score (AUASS) equal to or greater than 8] associated with BPH. A total of 74 volunteers will be recruited to participate in this clinical trial. Volunteers will include only males who are greater than 50 years of age and diagnosed with LUTS associated with BPH. They are Veterans who visit the Michael E. DeBakey Veterans Affairs Medical Center - Houston (MEDVAMC). There are no eligibility restrictions as to race or ethnicity.
his Phase 2 clinical research trial is a double-blind, randomized, placebo-controlled, parallel-group study to compare the treatment effects of onaBoNT-A 200 U versus 0.4 mg per day of oral tamsulosin in male Veterans diagnosed with moderate to severe LUTS [American Urologic Association Symptom Score (AUASS) equal to or greater than 8] associated with BPH. A total of 74 volunteers will be recruited to participate in this clinical trial. Volunteers will include only males who are greater than 50 years of age and diagnosed with LUTS associated with BPH. They are Veterans who visit the Michael E. DeBakey Veterans Affairs Medical Center - Houston (MEDVAMC). There are no eligibility restrictions as to race or ethnicity.
开始日期2012-06-01 |
100 项与 OnabotulinumtoxinA (VA Office of Research and Development) 相关的临床结果
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100 项与 OnabotulinumtoxinA (VA Office of Research and Development) 相关的转化医学
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100 项与 OnabotulinumtoxinA (VA Office of Research and Development) 相关的专利（医药）
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1,425
项与 OnabotulinumtoxinA (VA Office of Research and Development) 相关的文献（医药）2026-12-31·JOURNAL OF MEDICAL ECONOMICS
Real-world treatment switching and healthcare costs of onabotulinumtoxinA and calcitonin gene-related peptide monoclonal antibodies in Medicare patients with chronic migraine: a retrospective claims analysis
Article
作者: Dong, Yanan ; Mao, Ziling ; Dominguez, Annaliza ; Park, Tae Jin
AIMS:
Evaluate treatment switching and healthcare costs of onabotulinumtoxinA (onabotA) compared to calcitonin gene-related peptide (CGRP) monoclonal antibodies (mAbs) for the preventive treatment of chronic migraine (CM).
MATERIALS AND METHODS:
Adult patients with CM who initiated onabotA or a CGRP mAb between 1 October 2021 and 31 December 2023 were identified from the Optum de-identified Clinformatics Data Mart database. Index date was the first recorded treatment claim and patients must have had continuous Medicare coverage 12-months pre- and post-index period. Treatment switching, defined as ≥1 claim for a different branded migraine preventive treatment in the 12 months post-index period, was evaluated. Two additional treatment switch definitions were evaluated. All-cause healthcare resource utilization and costs were evaluated over the 12-month follow-up. Multivariable logistic regression adjusted for baseline characteristic differences when comparing odds of switching between onabotA and CGRP mAbs. Patient information on CM severity was not available in the database and not reported.
RESULTS:
Of 887 patients identified, 367 initiated onabotA and 520 a CGRP mAb as index treatment. After 12 months of follow-up, 8.7% of onabotA users and 18.3% of CGRP mAb users initiated a different branded migraine preventive treatment. After adjusting for differences in baseline characteristics, CGRP mAb users had 134% higher odds of switching treatment during the 12-month follow-up compared to onabotA users (OR, 2.34; 95% CI: 1.49, 3.67, p < 0.001), or 9.3% absolute risk difference. Results for additional treatment switch definitions were consistent. OnabotA and CGRP mAb users had comparable all-cause healthcare costs during the 12-month follow-up.
LIMITATIONS:
Outcomes could only be adjusted for known and observed confounders, which could introduce bias between comparators.
CONCLUSIONS:
Patients with CM on a CGRP mAb were significantly more likely to switch to a different branded migraine preventive treatment within 12 months of treatment initiation compared to those on onabotA. Total costs were comparable between treatments.
2026-12-31·JOURNAL OF MEDICAL ECONOMICS
Cost-utility of implantable tibial neuromodulation (Revi) versus conservative therapy for urgency urinary incontinence in adults: a US payer perspective
Article
作者: Amundsen, Cindy L. ; Niklewski, Paul J. ; Rodine, Peter R. ; Dmochowski, Roger R. ; Sutherland, Suzette E. ; Lenherr, Sara M.
AIMS:
Implantable tibial nerve neuromodulation (ITNM) represents a minimally invasive intervention for urgency urinary incontinence (UUI). This study evaluated the 3-year cost-utility of ITNM with an external wearable battery (Revi System) versus conservative treatments (behavioral ± pharmacotherapy) from a US payer perspective.
MATERIALS AND METHODS:
A cohort state-transition (Markov) model with annual cycles compared ITNM to conservative treatment modalities (behavioral ± pharmacotherapy). ITNM clinical parameters were derived from the OASIS pivotal trial (N = 150); parameter uncertainty was propagated via 20,000 Monte Carlo simulations. Health states captured responder and non-responder status with permitted transitions, rescue interventions (onabotulinumtoxinA, sacral neuromodulation, percutaneous tibial nerve stimulation), and downstream event modules (falls, urinary tract infection, incontinence-associated dermatitis, depression, cognitive decline/dementia, and nursing-home entry). Costs and quality-adjusted life-years (QALYs) were discounted at 3% annually and expressed in 2025 US dollars. Parameter uncertainty was assessed using probabilistic sensitivity analysis (PSA; 20,000 simulations) and tornado analysis.
RESULTS:
ITNM was both more effective and less costly than behavioral ± pharmacotherapy. Mean 3-year costs were $39,308 versus $43,737 (ΔCost = -$4,428), with mean QALYs of 2.188 and 1.940, respectively (ΔQALY = +0.249). The incremental cost-effectiveness ratio was -$17,818/QALY (dominant). Incremental net monetary benefit at $40,000/QALY was $14,369, with 100% probability of cost-effectiveness across thresholds from $20,000-$150,000/QALY. Key value drivers were responder utility and fall-related parameters.
LIMITATIONS:
The analysis adopts a US payer perspective with direct medical costs only. Some event risks were applied from population-level sources and may not fully capture patient-level heterogeneity. The 3-year base-case horizon may miss longer-term durability effects, though extended-horizon scenarios support consistent findings.
CONCLUSIONS:
Over 3 years, ITNM with an external wearable battery improves quality-adjusted survival and lowers overall payer costs compared with conservative therapies for UUI, supporting its inclusion as a value-consistent minimally invasive therapy.
2026-10-01·TOXICON
Efficacy and durability of therapies for neurogenic lower urinary tract dysfunction: A network meta-analysis of Botulinum Toxin a, instillations, and neuromodulation
Review
作者: Lan, Cunyu ; Wang, Heling ; Lei, Beibei ; Wang, Yage ; Zhuang, Weisheng ; Ma, Shenhong ; Zhang, Di ; Han, Qiaohua
OBJECTIVE:
To evaluate the short-term efficacy and long-term sustainability of botulinum toxin A (BTA), instillations, and neuromodulation for neurogenic lower urinary tract dysfunction (NLUTD). This analysis addresses the clinical need to balance immediate symptom relief with sustained therapeutic stability.
METHODS:
We searched databases through October 2025. Outcomes included maximum cystometric capacity (MCC), maximum detrusor pressure (MDP), and incontinence episode frequency (IEF). OnabotulinumtoxinA and AbobotulinumtoxinA were analyzed as distinct nodes to account for potency differences.
RESULTS:
Across 25 RCTs (3779 participants), most BTA regimens, capsaicin, and N/OFQ significantly increased short-term MCC. Abo-BTA 600U [MD = 174.57; 95% CI: 168.19, 180.94] and Abo-BTA 750U-30 [MD = 171.03; 95% CI: 133.71, 208.35] showed the greatest gains. Long-term, only Abo-BTA (500U, 750U-15/30) and FES maintained larger estimated effects for MCC/MDP. Regarding IEF, Abo-BTA 800U showed the largest short-term reduction [MD = -14.32; 95% CI: -18.16, -10.48], while only Abo-BTA 750U remained effective long-term, indicating time-dependent attenuation. rTMS was safest, whereas high-dose BTA increased risks.
CONCLUSION:
Detrusor-injected BTA demonstrates potential as a favorable intervention for NLUTD, with Abo-BTA(600U) or Ona-BTA(300U) exhibiting a balanced profile between efficacy and safety. Although the clinical benefits of most BTA formulations diminish over time, Abo-BTA (specifically 750U administered via 30 sites) ranked higher in statistical probability for long-term durability in this analysis. This longitudinal discrepancy may reflect a paucity of extended follow-up data for Ona-BTA rather than intrinsic therapeutic failure. These results suggest that higher injection-site density might be associated with enhanced treatment durability, while remaining interventions showed less consistent evidence of benefit compared with placebo. Given the indirect nature of the comparisons and the focus on single-injection data, these findings should be interpreted as exploratory.
8
项与 OnabotulinumtoxinA (VA Office of Research and Development) 相关的新闻（医药）2026-07-14
此部分内容仅为学习群每日更新的医美类文献名称汇总，文献为机翻仅供参考。我们会每周从国内外期刊上查找医美类或有一定关系的文献。供大家参考。方便学习群群友无法通过学习群查询到文献后通过公众号查询到相关文章。根据热度也可能做一些产品汇总文献。由于精力有限肯定存在错误，仅供参考。所有文献版权归属出版机构，汇总名称仅为方便从业人员了解（每日文献多数为出版社最近出版或更新的文献。）
7月14日
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67.Portable structured-light 3D volumetry for breast and flap assessment: technical validation and workflow development
68.The versatile menu of the nasolabial flap in nasal reconstruction: a defect-based algorithm
69.Patient education in the digital age: assessing the readability, quality, and actionability of keloid information online
70.Impact of seborrheic dermatitis on health-related quality of life: a qualitative analysis
71.Aggrecan expression in morphea tissues: a potential contributor to fibrotic extracellular matrix accumulation
72.Comparative efficacy and safety of isotretinoin regimens in Asian patients: a systematic review and meta-analysis
73.Characterization of collagen in human scar tissue at various stages of scar maturation using in vivo reflectance confocal microscopy
74.Special Considerations When Using GLP-1 Receptor Agonists in the Treatment of Obesity and Diabetes Mellitus Type 2 in Older Adults
75.Frequent Sweetened Beverage Consumption Is Associated With Accelerated Biological Aging: Evidence From a Population-Based Study and Gut Microbiota Analysis
76.The Benefits of Advanced Botulinum Neurotoxin Injection Training from a Spasticity Management Fellowship
77.IncobotulinumtoxinA Injection to Balance Eyebrows and Facial Shapes: A Review with Illustrative Clinical Examples
78.Three-dimensional three-interval thixotropy test (3D-3ITT) protocol for cosmetic lotions: A proof-of-concept study linking thixotropy to sensory and emotional responses
79.Bridging the gap between consumer perception and objective measurements: A novel multiview image analysis methodology for quantifying hair volume on a human head (curl type I to III)
80.Real-world evidence for the efficacy and tolerability of an isobutylamido-thiazolyl-resorcinol (Thiamidol)-containing skincare regimen on facial hyperpigmentation and overall skin appearance: A multi-centre study in 11 European countries
81.A Possible Role of Mycobiome in the Pathophysiology of Acne: Structured Narrative Review and Perspectives
82.MFAP4 Promotes Scar Formation by Regulating Macrophage-Myofibroblast Transformation Through Activation of the TGF-β/Smad3 Signalling Pathway
83.Polynucleotides and Polydeoxyribonucleotides for Skin Rejuvenation, Postoperative Scar Prevention, and Wound Healing: A Systematic Review of Randomized Clinical Trials
84.First Case Series on Ambulatorial Endoscopic Sleeve Gastroplasty for Morbidity Obesity: A Single Center Experience
85.Short-Term Clinical and Metabolic Outcomes of Laparoscopic Sleeve Gastrectomy in Korean Adolescents with Severe Obesity: A Retrospective Analysis
86.Neural Decision-Making and Affective Dynamics in Weight Regain after Metabolic and Bariatric Surgery: A Multimodal Longitudinal Computational Psychiatry Study
87.Beyond Initial Resolution: Predictors of Recurrence of Obesity-related Medical Conditions after Metabolic and Bariatric Surgery
88.Fractional CO2 Laser in Lichen Amyloidosis With Rapid Pruritus Resolution and Long-Term Remission: Serial PGP9.5 and Dylon Observations With Touch Sensitivity Assessment
89.Integrated single-cell and spatial transcriptomic analyses reveal an aging-associated fibroblast subtype linked to tumor progression in human skin
90.Microcore Skin Biopsies: A Novel, Micro-Invasive Skin Biopsy Technique Yielding Full-Thickness Histology
91.Topical Melatonin in Aesthetic Dermatology: From Cutaneous Melatoninergic Biology to Photoprotection, and Skin Rejuvenation
92.Fast-tracking dermatologic care for “VIP” patients: ethical concerns and practical approaches
93.Acneiform Eruption with Deucravacitinib: Systematic Review and Meta-Analysis
94.Topical Hypochlorous Acid for Acne Vulgaris: Mechanisms, Clinical Evidence, and Therapeutic Potential
95.Equity Evaluation: Analysis of the Prescribing Patterns of Isotretinoin Based on Reproductive Potential
96.Rosacea: We Still Haven’t Found What We’re Looking For
1. 鼻整形术对性生活活跃已婚女性性功能、自尊及抑郁症状的影响（更正）
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3. 无脱细胞真皮基质及补片的胸前乳房重建：呼吁比较性证据
4. 皮内注射10%葡萄糖（Sihler G）用于头皮毛发再生：一项随机、评估者设盲的预试验研究
5. 肌内臀部填充的技术演进：15年队列、5081例手术及高级臀部塑形术（MAG）的创立
6. A型肉毒毒素注射后骨骼肌的细胞重塑：一项单核RNA测序研究
7. A型肉毒毒素：迷思、证据与全球媒体叙事
8. 激光、微针及联合疗法治疗中重度萎缩性痤疮瘢痕：一项系统综述与网状Meta分析
9. 肌肉作为眉间肉毒毒素注射的基本治疗单元：技术描述与初步临床经验
10. A型肉毒毒素通过抑制TGF-β1/Smad通路减轻兔耳模型增生性瘢痕形成（更正）
11. 致编辑的信回复：《肌内效贴作为外部机械疗法：将其作用从乳腺手术拓展至身体塑形》
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14. 先天性单睑与重睑的睑板前纤维脂肪筋膜层：一项尸体、组织学及超声研究
15. 面部自体脂肪移植后脂肪坏死：已报道并发症及处理策略的系统综述
16. 血管紧张素Ⅱ作为烧伤后增生性瘢痕评估与预测的新型生物标志物：一项倾向评分匹配队列研究
17. 美容外科领域医患信任多维测量量表的构建方案
18. CO₂激光消融术与锥切术治疗宫颈上皮内瘤变2级：一项前瞻性队列研究
19. 点阵微针射频治疗光老化及萎缩性痤疮瘢痕：两种设备的半脸临床观察
20. 强脉冲光（IPL）、脉冲染料激光（PDL）与Q开关掺钕钇铝石榴石（Nd:YAG）激光治疗中重度炎症性痤疮的疗效与安全性比较：一项三臂随机对照临床试验
21. 保留皮肤清创联合负压滴注滞留伤口治疗早期坏死性筋膜炎
22. 90度叶旋转的岛状双叶皮瓣修复基底细胞癌切除后鼻尖缺损
23. 超微血管成像增强淋巴超声用于淋巴水肿相关淋巴管静脉吻合术前定位
24. 腹壁下深动脉穿支皮瓣乳房重建联合血管化淋巴结移植及腹壁整形的一体化显微外科康复
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26. 神经源性胸廓出口减压术中采用再生性周围神经界面处理锁骨上神经横断
27. 照亮黑暗：吲哚青绿血管造影评估晚期动静脉环血栓后游离皮瓣自主血运重建
28. 负压伤口治疗调节铜绿假单胞菌感染猪伤口的pH值及细菌侵袭
29. DIEP皮瓣重建中双穿支的血流动力学优势
30. 解读至关重要：回顾性外科研究中的常见统计学陷阱
31. 为整形外科医生构建实用人工智能工具：Cowork分步指南
32. 患者对透明质酸填充剂的认知误区：基于经验的思考
33. 鼻整形术后镜像对峙困扰：患者报告结局测量工具的开发与验证
34. 稀释型羟基磷灰石钙羧甲基纤维素（Radiesse）治疗颈胸区皱纹：成年女性的安全性与有效性
35. 整形外科中的人工智能：100篇最高被引英文出版物的文献计量学与可视化分析
36. 乳房植入物及肋骨骨髓炎中的偶发分枝杆菌感染：一例病例报告及文献复习
37. 超稀释羟基磷灰石钙注射联合点阵微针射频改善膨胀纹：一项预试验研究
38. 一次手术、多根神经、多样疼痛表型：面部透明质酸注射后三叉神经病理性疼痛四例病例系列
39. 采用预修剪法的非剃发毛囊单位提取及大剂量毛发移植：巴西外科团队经验
40. 乳蛋白水解物对自觉皮肤暗沉女性皮肤质量及晚期糖基化终末产物的影响：两项为期8周的随机对照试验
41. 蜂蜜作为化妆品配方中保湿成分的功效：临床试验的系统综述
42. 面部美容外科中的光生物调节疗法：疗效与安全性的系统综述
43. 化学剥脱术在色素性皮肤病治疗中的应用进展
44. Q开关Nd:YAG激光去除艺术性及美容性纹身
45. 损伤病因与瘢痕结局的关联：一项回顾性临床研究
46. 上面部皱纹神经毒素注射时机
47. 大剂量多通道射频治疗对内脏及皮下腹部脂肪的影响：一项干预前后研究
48. 化妆品使用及其潜在风险：印度旁遮普地区公众认知与态度评估
49. 外用曲法罗汀治疗马来西亚寻常痤疮的疗效与耐受性：一项单臂、开放标签、观察性研究
50. 多核苷酸注射后面部双侧革兰阴性脓肿
51. 双平面生物刺激剂注射中的平面-厚度等分匹配探讨
52. 羟基磷灰石钙用于中国人群颞部轮廓修复的临床及三维评估
53. 采用尖端超声技术研究安全填充剂注射技术
54. 神经美学应用于美容医学的概念与披露考量
55. 植入物相关ASIA及乳房植入物疾病中的全身症状模式：一项研究水平描述性系统综述
56. 寻常痤疮中的睡眠-压力-皮肤轴
57. 采用高能量密度1064nm皮秒激光的统一黄金参数疗法无副作用去除纹身
58. 含补骨脂酚与水杨酸的护肤霜治疗轻中度寻常痤疮的疗效与安全性：一项非劣效性随机对照试验
59. 外用山椒素衍生制剂治疗黄褐斑的疗效与安全性：一项随机、双盲、安慰剂对照试验
60. 评射频微针与点阵二氧化碳激光治疗面部萎缩性痤疮瘢痕的疗效、恢复及色素安全性比较：一项前瞻性随机半脸试验
61. 证据合成中的人工智能：益处、局限及透明报告的重要性
62. 近红外血管定位引导浅表皮肤血管病变的操作处理
63. 儿科患者的中央离心性瘢痕性脱发：一项回顾性分析
64. 透明质酸、氨基酸与维生素的焕活复合物促进人体皮肤微循环
65. 90天护肤方案期间皮肤变化的仪器与患者报告评估：一项前瞻性单臂观察性研究
66. 澳大利亚人群BODY-Q模块常模数据及与北美、欧洲常模的比较
67. 便携式结构光三维容积测量用于乳房及皮瓣评估：技术验证与工作流程开发
68. 鼻唇沟皮瓣在鼻重建中的多样化应用：基于缺损的算法
69. 数字时代的患者教育：在线瘢痕疙瘩信息可读性、质量及可操作性评估
70. 脂溢性皮炎对健康相关生活质量的影响：一项质性分析
71. 硬斑病组织中聚集蛋白聚糖的表达：纤维化细胞外基质积聚的潜在促成因素
72. 亚洲患者异维A酸方案的疗效与安全性比较：一项系统综述与Meta分析
73. 采用在体反射式共聚焦显微镜表征不同瘢痕成熟阶段人体瘢痕组织中的胶原
74. 老年肥胖及2型糖尿病患者使用GLP-1受体激动剂的特殊考量
75. 频繁饮用含糖饮料与生物衰老加速相关：来自人群研究及肠道菌群分析的证据
76. 痉挛管理专科进修带来的高级肉毒神经毒素注射培训收益
77. IncobotulinumtoxinA注射平衡眉形与面型：附临床示例的综述
78. 化妆品乳液的三维三区间触变性测试（3D-3ITT）方案：触变性与感官及情绪反应关联的概念验证研究
79. 弥合消费者感知与客观测量之间的差距：一种量化人体头部发量的新型多视角图像分析方法（Ⅰ-Ⅲ型卷发）
80. 含异丁基酰胺基-噻唑基-间苯二酚（Thiamidol）护肤方案改善面部色素沉着及整体皮肤外观的真实世界证据：11个欧洲国家的多中心研究
81. 真菌组在痤疮病理生理学中的可能作用：结构化叙述综述与展望
82. MFAP4通过激活TGF-β/Smad3信号通路调控巨噬细胞-肌成纤维细胞转化促进瘢痕形成
83. 多核苷酸与聚脱氧核苷酸用于皮肤年轻化、术后瘢痕预防及伤口愈合：随机临床试验的系统综述
84. 门诊内镜下袖状胃成形术治疗病态肥胖的首批病例系列：单中心经验
85. 韩国重度肥胖青少年腹腔镜袖状胃切除术的短期临床与代谢结局：一项回顾性分析
86. 代谢与减重手术后体重反弹中的神经决策与情感动力学：一项多模态纵向计算精神病学研究
87. 超越初始缓解：代谢与减重手术后肥胖相关疾病复发的预测因素
88. 点阵CO₂激光治疗淀粉样变苔藓伴瘙痒快速缓解及长期缓解：PGP9.5与Dylon系列观察及触觉敏感性评估
89. 单细胞与空间转录组整合分析揭示与人体皮肤肿瘤进展相关的衰老相关成纤维细胞亚型
90. 微芯皮肤活检：一种可获取全层组织学的新型微创皮肤活检技术
91. 美容皮肤科中的外用褪黑素：从皮肤褪黑素能生物学到光防护及皮肤年轻化
92. "VIP"患者皮肤科快速通道诊疗：伦理考量与实践路径
93. 氘可来昔替尼所致痤疮样皮疹：系统综述与Meta分析
94. 外用次氯酸治疗寻常痤疮：机制、临床证据及治疗潜力
95. 公平性评估：基于生育潜力的异维A酸处方模式分析
96. 玫瑰痤疮：我们仍未找到真正的答案
文献求助
1.Preserving the Modiolus: Enhanced Functional and Aesthetic Restoration with the Modified Bernard-Webster Technique in Lip Reconstruction（暂无）
2.Real-Time Integration of Patient-Reported Outcomes in Breast Cancer Surgery: Feasibility of the BREAST-Q REACT（暂无）
3.Why Plastic Surgery Must Rethink Residency Capacity
4.Seeing Clearly, Working Comfortably: 3D Exoscopes in Cleft Surgery Ergonomics and Education（暂无）
5.Exploring the Role of Fascia Lata Suspension in Triple Nerve Transfer for Facial Reanimation: A Comparative Outcomes Study
6.Vertical Superior Epigastric Artery Perforator Flap for Autologous Breast Augmentation After Massive Weight Loss（暂无）
7.The Impact of Nontobacco Nicotine Dependence on Postoperative Complications in Reconstructive and Aesthetic Breast Surgery Procedures: A Multicenter Propensity-Score Matched Analysis.（暂无）
8.Simultaneous Mastopexy-Augmentation for Small Ptotic Breasts
9.Gut Microbiota Shapes the Effects of Saturated and Polyunsaturated Fatty Acids on Skin and Hair Follicle Homeostasis
10.Kit signaling is involved in hair follicle morphogenesis and regeneration in mice（暂无）
7月9日
1.Response to Letter to the Editor, Discussion On: “Saying No in Aesthetic Surgery: Ethical Framework for Declining High-Stakes Requests
2.A Four-Color Aesthetic Evaluation System for Auricular Keloids: A Pilot Retrospective Cohort Study Based on Contour Integrity and Social-Distance Visibility
3.Application of the Double Wedge Resection Technique in the Correction of Labia Minora Hypertrophy Combined with Redundant Clitoral Hood
4.Cell-Assisted Lipotransfer (CAL) and Stromal Vascular Fraction (SVF) in Combination with Autologous Breast Reconstruction: A Preliminary Feasibility Case Series
5.Association of AbobotulinumtoxinA and Skinbooster for Periorbital Wrinkles: A Randomized, Controlled, Double-Blind, Split-Face Study
6.Liposuction for Lipedema Significantly Reduces Benzodiazepine Dependence: A Prospective Cohort Study
7.The Efficacy of Laser and Botox Therapies for Post-Thyroidectomy Scar Management: A Comprehensive Systematic Review and Meta-Analysis
8.Therapeutic Effect of Niclosamide versus Triamcinolone on Rabbit Ear Model of Hypertrophic Scar
9.Comparison of Dorsal Preservation Rhinoplasty and Dorsal Hump Reduction Rhinoplasty: A Systematic Review and Meta-Analysis of Postoperative Outcomes
10.Redefining Gynecomastia Surgery: Subtle Changes and Naturalistic Results
11.Comments on “Comparison of the Effects of Conventional and Piezoelectric Osteotomy on Intracranial Pressure Changes in Rhinoplasty Using Ultrasonographic Measurement of Optic Nerve Sheath Diameter”
12.Predicting “Ideal” Breast Proportionality to Support Implant Selection in Breast Augmentation
13.Management of the Buccal Fat Pad During Deep-Plane Facelift: Technique, Safety, and Aesthetic Outcomes in 68 Patients
14.Subpectoral Breast Fixation with Dermoglandular Inferior Pedicle: The “Dual Plane Autoprosthesis Technique
15.The First Nationwide Mapping of Aesthetic Treatments in Medicine in Central Europe: A Descriptive Observational Analysis
16.Body Image as a Mediating Mechanism in the Association Between Media Literacy and Acceptance of Cosmetic Surgery Among Young Adults
17.Prolene Suture Suspension Within a Multimodal Facial Rejuvenation Protocol: A 30-Year Experience
18.Distinct Molecular Signature of Earlobe Keloids: Integrated Transcriptomic Analysis of Extracellualr Matrix, Metalloproteinase, and Metabolic Pathways
19.Evolution of Facial Assessment in Aesthetic Medicine: 3D Imaging, Digital Analysis, and Patient-Reported Outcomes
20.Comparative Evaluation of Argon and Helium Plasma for Controlled Epidermal Peeling and Dermal Remodeling in Human Skin Tissue
21.Computational Trial of Prophylactic Biostimulator Interventions to Mitigate Facial Sagging Associated With GLP-1 Receptor Agonist Induced Weight Loss
22.No-Vertical-Scar Reduction Mammaplasty in Asian Patients: A Comparison of Superior Versus Inferior Pedicle Techniques
23.Integrated Surgical and Nonsurgical Approaches to Chin Augmentation: Our Clinical Algorithm and Technique
24.From Etiology to Aesthetic Surgery: Mapping Knowledge Domains and Emerging Trends in Gynecomastia Research: 35-Year Bibliometric Analysis
25.Prophylactic Local Antibiotic Therapy in Tissue Expander-Based Breast Reconstruction: A Systematic Review and Meta-Analysis
26.Modified Hotz Operation Combined with Modified Medial Canthoplasty to Correct Congenital Lower Eyelid Epiblepharon in a Chinese Population
27.Technical Considerations for Peripheral Nerve Sheath Tumor Excision With Intraoperative Neuromonitoring and Magnification
28.Detection of Microvascular Failure Using Bioimpedance and Sensor-derived Clinical Indicators: A Preliminary Study
29.VasSurDetect: An AI-based Chatbot for Rapid, Photo-based Feedback in Microsurgical Suturing Training
30.Hexahedral Graft Bed Formation Enhances Outcomes in Secondary Alveolar Bone Grafting: Surgical Technique and Graft Volume Thresholds
31.Dorsal Width and Functional Outcomes with use of Autospreader Flaps in Cosmetic Rhinoplasty
32.Non-contrast Magnetic Resonance Angiography Versus Contrast-enhanced Computed Tomography in Deep Inferior Epigastric Perforator (DIEP) Flap Planning: A 4-year Non-inferiority Cohort Study
33.Clinical Evidence and Commercial Landscape of Topical Exosomes for Skin Rejuvenation: A Scoping Review
34.Subdomal Graft Control of Nasal Tip Aesthetics: A Long-term Digital Photographic Evaluation
35.Assessment of Skin Physiology Changes, Efficacy, and Safety of a New Complex Herbal Cream: A 4-Week Multi-Center, Open-Label, Prospective Study of Patients With Sensitive Skin and Rosacea
36.Lipedema or Advanced Cellulite? A Diagnostic Boundary in Need of Definition
37.Efficacy and Tolerability of a Tri-Acid Dermocosmetic Serum in Adults of Any Skin Phototype With Mild to Moderate Acne
38.Anti-aging research – where are we heading?
39.Synergistic Effects of Intense Pulsed Light and Glycolic Acid on Photoaging and the Involvement of CD26 in Photoprotection
40.A Comparison Between the Therapeutic Efficacy and Safety of Microneedling With Ascorbic Acid Versus CO2 Fractional Laser With Ascorbic Acid in the Treatment of Striae
41.Clinical Efficacy and Safety of Photodynamic Therapy for Treating Rosacea: A Systematic Review and Meta-Analysis
42.Differentiation Between Eccrine Poroma and Pyogenic Granuloma Based on Dermoscopic Features
43.Clinicotrichoscopic Patterns of Alopecia and the Prevalence of Thyroid Dysfunction in a Dermatology Outpatient Setting: A Cross-Sectional Study
44.Enhancement of Collagen and Elastic Fibers by Direct Contact Cooling–Based Monopolar Radiofrequency in a Minipig Model
45.PVA Microsphere Injection Rhinoplasty with Surgical-Like Injection Technique for Asia Female Patients: A 30-Case Clinical Study
46.Associations of Sleep Quality and Perceived Stress with Skin, Scalp, and Hair Health Among 1,017 Chinese Women: A Cross-Sectional Observational Study
47.Commentary on exploring the mechanism of differential responses to combination therapy in melasma: pigmentary versus mixed pigmentary–vascular types—a clinical study based on interaction analysis
48.Artificial Intelligence in Evidence Synthesis: Benefits, Limitations, and the Importance of Transparent Reporting
49.Disparities in care of infantile hemangiomas: a retrospective cohort study measuring the impact of area deprivation, race and ethnicity
50.Racial Differences in Frontal Fibrosing Alopecia: A 10-Year Single-Center Retrospective Cohort Study
51.Real-World Effectiveness and Safety of Ritlecitinib in Adolescents with Severe Alopecia Areata: A 36-Week Single-Center Study
52.A Preliminary Study Evaluating the Potential of a Topical Hydrating Formulation Enriched with Platelet-Rich Plasma for Improving Skin Texture
53.Cosmetic outcomes of postoperative scar taping after surgical incisions: A systematic review
54.Management of post-operative pseudomonas aeruginosa infection in head and neck free flap patients: systematic review and case series
55.Pediatric Septorhinoplasty: A Cohort Study Utilizing the Pediatric Health Information System (PHIS) Database
56.Three-Dimensional Prediction of Nasal Growth Using Landmark-Based Morphometry: Clinical Validation of a Predictive Algorithm
57.Defining Dermal Matrices: Results of a Global Delphi Panel in Surgical Reconstruction
58.Tissue Response to the Use of Synthetic and Biological Meshes in Implant-Based Breast Surgery: A Histomorphological Case-Series of Six Patients
59.Assessment and Reporting of Nipple-Areola Complex Sensation After Reduction Mammaplasty: A Scoping Review
60.Correspondence On: Implementation Standards for Ready-to-Use Three-Dimensional Printed Constructs in Autologous Breast Reconstruction
61.Concentration-Dependent Nonlinear Rheology of Agar Hydrogels
62.Fibrin-Based Biomaterials in Wound Healing and Soft Tissue Regeneration: Biological Mechanisms and Clinical Applications
63.From ECM Aging to Mechanobiological Restoration: Injectable Fillers and Dermal Fibroblast Mechanotransduction—A Narrative Review
64.Long Distance Non-Contact Dermoscopy: Technological Foundations, Clinical Applications, and Future Directions
65.Fibroblast State Remodelling and Stromal Depletion Shape the Ageing Microenvironment of Human Penile Skin
66.A Review of Randomized Controlled Trials for Vitiligo Therapies Published Between 2013 and 2023
67.It Is Time to End Routine Laboratory Monitoring for Isotretinoin
68.The double-edged sword of generative AI in dermatology: a multi-component cross-sectional study on physician burnout, patient satisfaction, and communication quality
69.Die globale Belastung durch postadoleszente Akne: eine Analyse der Trends bei 25- bis 49-jährigen Erwachsenen von 1990 bis 2021
70.Verzögerte Überempfindlichkeitsreaktion nach Mesotherapie mit einer lipolytischen Lösung auf Phosphatidylcholinbasis
71.Klassisches Kaposi-Sarkom der oberen Extremität als Folge eines Lymphödems, erfolgreich mit Nd:YAG-Laser behandelt
72.Dramatische Rettung bei Kalziumchlorid-Extravasation durch Hyaluronidase-Injektion
73.S3-Leitlinie Diagnostik und Therapie der Alopecia areata – Teil 1: Diagnostik und Epidemiologie
74.Cutaneous inflammatory biomarkers in rosacea and their association with disease severity
75.Pre-Post Evaluation of a Sun Safety Social Media Campaign for Young Adults to Reduce Skin Cancer Risk
76.Oncoplastic Reconstruction of the Contralateral Breast Using the Liacyr Pedicle without Prosthetic Implants
77.Latissimus Dorsi Thoracolateral Flap: A New Option for Total Autologous Breast Reconstruction
78.Bilateral Superior Gluteal Artery Perforator (SGAP) Flaps for Total Gluteal Reconstruction After Extensive Hidradenitis Suppurativa
79.Ultrasound Analysis of Fat Grafting in Breast Reconstruction
80.Low-Cost Synthetic Model for Liposuction Training and Simulation
81.Eutrophic Facelift: A Less-Invasive Alternative to Rhytidoplasty
82.Hybrid Implant: Initial Study with 279 Units of an Innovative Breast Implant
83.Complications from the Facial Application of Injectables: Botulinum Toxin and Hyaluronic Acid
84.Indications and Outcomes of the Clinical and Surgical Treatments of Lipedema: A Literature Review
85.Technical Differentiation and Innovation in Contemporary Liposuction: A Critical Study of the Postoperative Period in Light of New Technologies
86.High-Definition Liposuction Assisted by a Third-Generation Ultrasound Device: Retrospective Analysis of Postoperative Outcomes
# 7月9日
1. 致编辑来信回复：探讨《美容外科中的拒绝原则：高风险诊疗诉求回绝的伦理框架》
2. 耳廓瘢痕疙瘩四色美学评估体系：基于轮廓完整性与社交可视距离的回顾性先导队列研究
3. 双楔形切除术在小阴唇肥大合并阴蒂包皮过长矫正术中的应用
4. 细胞辅助脂肪移植术联合血管基质片段应用于自体乳房重建：初步可行性系列病例研究
5. AbobotulinumtoxinA联合Skinbooster改善眼周皱纹：随机对照双盲半脸对照研究
6. 脂肪抽吸术治疗淋巴水肿可显著降低苯二氮䓬类药物依赖：前瞻性队列研究
7. 激光与肉毒毒素疗法用于甲状腺术后瘢痕修复的疗效：全面系统综述与荟萃分析
8. 氯硝柳胺与曲安奈德作用于兔耳增生性瘢痕模型的治疗效果对比
9. 鼻背保留隆鼻术与驼峰鼻削除隆鼻术术后疗效对比：系统综述及荟萃分析
10. 男性乳房发育矫正术全新理念：精细化调整与自然化手术效果
11. 评述《利用视神经鞘直径超声检测对比常规截骨与压电截骨隆鼻术对颅内压变化的影响》
12. 测算理想乳房比例，为隆胸手术假体选择提供参考
13. 深层面部除皱术中颊脂垫的处理方式：68例患者手术技巧、安全性及美学疗效分析
14. 乳腺下胸肌间隙固定联合乳腺腺体下蒂术式：双平面自体塑形技术
15. 中欧地区医美诊疗项目首次全国性调研：描述性观察分析
16. 体象认知在青年人群媒介素养与医美手术接受度间的中介机制研究
17. 聚丙烯缝线悬吊技术在多元化面部年轻化方案中的应用：三十年临床应用总结
18. 耳垂瘢痕疙瘩特异性分子特征：细胞外基质、金属蛋白酶及代谢通路整合转录组学分析
19. 医美领域面部评估体系的发展：三维成像、数字化分析与患者自评结局
20. 氩气等离子体与氦气等离子体用于人体皮肤可控表皮剥脱及真皮重塑的对比评估
21. 预防性生物刺激剂干预改善GLP-1受体激动剂减重引发面部松弛的模拟试验研究
22. 亚洲人群无垂直瘢痕乳房缩小术：上蒂法与下蒂法术式对比研究
23. 隆颏手术与非手术联合综合诊疗方案：临床诊疗思路与操作技术
24. 从病因探究到美容外科矫治：35年来男性乳房发育研究知识图谱与前沿趋势的文献计量分析
25. 组织扩张器辅助乳房重建术中局部预防性抗生素用药：系统综述与荟萃分析
26. 改良霍茨术联合改良内眦成形术矫正中国人群先天性下睑赘皮
27. 联合术中神经监测与显微放大技术实施周围神经鞘瘤切除术的技术要点
28. 依托生物阻抗及传感器临床指标检测微血管功能障碍的初步研究
29. VasSurDetect：基于人工智能、可快速拍照反馈的显微缝合训练智能助手
30. 六面体植骨床制备优化二期牙槽骨移植疗效：手术术式与植骨量临界标准
31. 美容隆鼻术中自体撑开软骨瓣对鼻背宽度及鼻部功能预后的影响
32. 非增强磁共振血管造影与增强CT在下腹壁深血管穿支皮瓣术前规划中的应用对比：为期四年的非劣效性队列研究
33. 外用外泌体用于皮肤年轻化的临床证据与市场现状：范围综述
34. 穹窿间移植物调控鼻尖美学形态：长期数字化影像随访评估
35. 新型复方草本乳膏对敏感肌及玫瑰痤疮患者皮肤生理状态、疗效与安全性评价：为期4周多中心开放前瞻性研究
36. 淋巴水肿还是重度蜂窝织炎：亟待界定的临床诊断标准
37. 复合三酸护肤精华对各肤色轻中度痤疮成年患者的疗效及耐受性研究
38. 抗衰老研究未来发展方向探析
39. 强脉冲光联合乙醇酸改善光老化的协同作用及CD26在皮肤光防护中的作用
40. 微针联合抗坏血酸与二氧化碳点阵激光联合抗坏血酸治疗膨胀纹的疗效及安全性对比
41. 光动力疗法治疗玫瑰痤疮的临床疗效与安全性：系统综述及荟萃分析
42. 借助皮肤镜特征鉴别小汗腺汗孔瘤与化脓性肉芽肿
43. 皮肤科门诊脱发患者毛发镜分型及甲状腺功能异常患病率：横断面研究
44. 基于直接接触冷却的单极射频技术促进小型猪皮肤胶原与弹性纤维增生的实验研究
45. 采用类手术注射方式的PVA微球注射隆鼻术应用于亚洲女性：30例临床研究
46. 1017名中国女性睡眠质量、心理压力与头皮及毛发健康的相关性横断面观察研究
47. 评述黄褐斑联合治疗疗效差异机制研究：色素型与色素血管混合型基于交互分析的临床研究
48. 人工智能在循证医学证据整合中的应用：优势、局限与透明化报告的重要性
49. 婴幼儿血管瘤诊疗资源分配差异：基于地域贫困程度、种族民族影响的回顾性队列研究
50. 种族差异与额部纤维化性脱发：单中心十年回顾性队列研究
51. Ritlecitinib治疗青少年重度斑秃的真实世界疗效与安全性：为期36周单中心研究
52. 富血小板血浆外用保湿制剂改善肤质效果的初步探究
53. 手术切口术后减张贴敷的美容预后效果：系统综述
54. 头颈部游离皮瓣术后铜绿假单胞菌感染的防治方案：系统综述与系列病例分析
55. 儿童鼻中隔鼻成形术：基于儿童健康信息系统数据库的队列研究
56. 依托标志点形态测量法实现鼻部发育三维预测：预测算法临床验证
57. 真皮基质材料定义标准：全球外科重建领域德尔菲专家共识研究结果
58. 假体置入式乳房整形术中人工合成补片与生物补片的组织反应：6例组织形态学系列病例研究
59. 乳房缩小术后乳头乳晕复合体感觉功能评估与研究现状：范围综述
60. 通讯论述：自体乳房重建术中成品化三维打印植入材料的应用规范
61. 琼脂水凝胶浓度依赖性非线性流变特性
62. 纤维蛋白基生物材料在创面愈合与软组织修复中的作用机制及临床应用
63. 从细胞外基质衰老到力学生物学修复：注射填充剂与真皮成纤维细胞力传导机制综述
64. 远距离非接触式皮肤镜：技术原理、临床应用与发展前景
65. 成纤维细胞状态重塑与基质耗竭调控人类阴茎皮肤衰老微环境
66. 2013-2023年白癜风治疗随机对照试验研究综述
67. 异维A酸常规实验室监测手段停用的必要性探讨
68. 生成式人工智能在皮肤科领域的双刃剑效应：医师职业倦怠、患者满意度及医患沟通质量的多维度横断面研究
69. 成年后痤疮全球疾病负担：1990至2021年25-49岁人群发病趋势分析
70. 磷脂酰胆碱类溶脂溶液皮下注射疗法引发迟发性过敏反应
71. 继发于淋巴水肿的上肢经典型卡波西肉瘤经Nd:YAG激光成功治愈
72. 透明质酸酶注射紧急救治氯化钙外渗损伤
73. 斑秃诊疗S3指南——第一部分：诊断与流行病学
74. 玫瑰痤疮皮肤炎症生物标志物及其与病情严重程度的相关性
75. 面向青年群体的防晒科普社交媒体活动降低皮肤癌风险的前后效果评估
76. 无假体置入前提下利用Liacyr蒂瓣实施对侧乳房肿瘤整形重建术
77. 背阔肌胸外侧皮瓣：全新全自体乳房重建术式
78. 双侧臀上动脉穿支皮瓣用于重度化脓性汗腺炎术后全臀重建
79. 乳房重建术中脂肪移植的超声影像学分析
80. 低成本仿真模型在脂肪抽吸术教学模拟训练中的应用
81. 营养平衡式面部年轻化手术：传统除皱术的微创替代方案
82. 复合型乳房假体：279例新型乳房假体初步临床研究
83. 面部注射类制剂相关并发症：肉毒毒素与透明质酸
84. 淋巴水肿临床及手术治疗的适应症与预后效果研究综述
85. 当代脂肪抽吸术技术分化与创新：基于新型技术的术后恢复阶段深度研究
86. 第三代超声辅助高清脂肪抽吸术：术后疗效回顾性分析
文献求助
1.Clinical Risk and Regulatory Oversight for Office-Based Cosmetic Procedures: A State-By-State Analysis
2.Poly-l -Lactic Acid Safety Over the Past 5-years: Analysis of US Food and Drug Administration Database Reports (2020–2025)
3.Periorbital Changes Following Glucagon-Like Peptide-1 Receptor Agonist Use: A Retrospective Cohort Study of Oculofacial Complications and Interventions
4.One-day rejuvenation: a preliminary case series of a multimodal protocol combining Q-switched 1064 nm laser, botulinum toxin, and laser-assisted delivery of PDRN and retinoids
5.A body-wide atlas for murine hair cycle dynamics
6.Microsurgical Anatomy and Surgical Relevance of the Internal Frontal Arteries: A Cadaveric Anatomic Study
7.In-vivo comparison of the neurotoxic potencies of incobotulinumtoxinA, onabotulinumtoxinA, and abobotulinumtoxinA
8.In silico multiscale computational modelling of botulinum toxin a diffusion for glabellar wrinkle treatment: Optimizing injection volumes across formulations
1. 诊室美容操作的临床风险与监管：各州分析
2. 聚左旋乳酸过去5年的安全性：美国食品药品监督管理局数据库报告分析（2020–2025）
3. 胰高血糖素样肽-1受体激动剂使用后的眶周变化：眼面部并发症与干预措施的回顾性队列研究
4. 一日焕颜：联合调Q 1064 nm激光、肉毒毒素及激光辅助递送PDRN与维A酸类药物的多模式方案初步病例系列
5. 小鼠毛发生长周期全身动态图谱
6. 额内侧动脉的显微外科解剖及其外科意义：尸体解剖学研究
7. incobotulinumtoxinA、onabotulinumtoxinA与abobotulinumtoxinA神经毒力的体内比较
8. 眉间纹治疗中A型肉毒毒素扩散的多尺度计算机模拟：不同制剂注射体积的优化
7月8日皮肤
1.斑秃患者血清Th1_Th2_Th17_Treg细胞因子的表达及其临床意义_吴恺悦.pdf
2.瘢痕形成的多轴耦合网络调控机制及工程化干预策略研究进展_沈非凡.pdf
3.M1_M2巨噬细胞外泌体通过特异性miRNA介导的信号通路调控瘢痕形成机制_余南生.pdf
4.火针联合光动力疗法对难治性痤疮皮损修复及瘢痕预防的疗效研究_钟维.pdf
5.胶原头皮护理精华液对雄激素性脱发小鼠毛发生长的影响_肖玲.pdf
6.从机制到靶点：皮肤光老化的表观遗传调控研究进展_潘洋.pdf
7.脂代谢异常与女性型脱发发生发展的相关性研究_廖钟敏.pdf
8.粪菌移植在皮肤科的应用前景-蔡志成赵阳陈韦君张玲杨桂兰.pdf
9.瘢痕疙瘩药物靶点预测：多组学孟德尔随机化分析-博文平罗银利赵蕾娜荷芽高翠丽崔艾丽金哲虎.pdf
10.长脉冲1064_nm_Nd__YAG激光联合2%盐酸卡替洛尔滴眼液外用治疗婴幼儿血管瘤疗效评价_孙丽娜.pdf
11.瘢痕疙瘩病灶局部注射操作专家共识-中国整形美容协会护理分会申琳李峰周勇.pdf
12.皮肤镜在基底细胞癌诊断及治疗中的应用-褚丹祝立丽李晓东赵佳宇韩阳.pdf
13.3种手术方式治疗儿童四肢中型先天性色素痣临床疗效观察_刘琪.pdf
14.皮肤镜检查在女性休止期脱发和女性雄激素性脱发诊断中的作用-房灵秦凤.pdf
15.微针疗法在黄褐斑中的应用进展-苏孟李海涛.pdf
16.大气压冷等离子体治疗轻中度痤疮临床研究_赵艳君.pdf
17.利特昔替尼治疗成人斑秃及儿童普秃2例_陈溪.pdf
18.皮肤创面多重耐药菌感染的菌群分布与耐药性分析-赵小丹宗岩周旋.pdf
19.基于蛋白质组学倍他米松联合染料激光治疗增生性瘢痕机制研究-隋诗佳吴佳敏刘旭葵王旭东杨佳曼夏志宽李海涛杨蓉娅.pdf
20.瘢痕疙瘩与特应性皮炎潜在关键共同生物标志物的筛选及白藜芦醇对瘢痕疙瘩成纤维细胞体外作用研究-刘家希王思慧丰叶琪布文博周炳荣鲁严.pdf
21.雄激素性秃发患者对不同配方米诺地尔制剂的斑贴试验结果分析-王英杨顶权.pdf
22.异维A酸治疗面部多发皮脂腺增生一例_潘伟军.pdf
23.光线性角化病132例临床分型与皮肤镜特征分析_薛月萃.pdf
24.点阵激光联合自体微颗粒脂肪移植修复面部痤疮瘢痕皮肤屏障的效果-林乐乐张亚男王锦慧.pdf
25.异维A酸软胶囊联合消痤面膜治疗中重度痤疮的临床疗效观察_李旭芳.pdf
26.基于数据挖掘、网络药理学和分子对接分析中药治疗雄激素性秃发的用药规律与机制_冯鹤.pdf
27.毛发再生的机制及临床转化研究进展_冯南飞.pdf
28.c-nu小鼠皮肤光老化蛋白组学分析-徐远飞唐伟龚春梅杨慧.pdf
29.《皮肤病家庭紫外线光疗规范》要点解读_胡煜.pdf
7月8日中国医疗美容
1.超脉冲二氧化碳激光祛除面部色素痣的临床效果及其影响因素探讨-郭学娜陈盼盼刘方真李艳.pdf
2.舒缓修复联合分级干预模式对痤疮敏感肌患者激光术后皮肤反应及满意度的影响分析_赖色玉.pdf
3.四关活血法针刺联合桃花灸治疗肝郁气滞兼血瘀型黄褐斑的疗效分析-杨璐康艳杨春海.pdf
4.两侧双切口脂肪抽吸联合大汗腺微创剪除术治疗腋臭的临床效果研究_王兆楠.pdf
5.水刀辅助小切口微创手术联合自制封闭负压引流技术在腋臭治疗中的应用_袁东亮.pdf
6.生长发育高峰期不同矢状骨面型高角患者颞下颌关节形态的CBCT研究_诸葛南山.pdf
7.富血小板血浆在瘢痕治疗中的进展-刘新宇陈宁杰张瑾王海涛.pdf
8.浅谈公立医院医疗美容主诊医师职业发展路径-本刊编辑部.pdf
9.颧部褐青色斑激光治疗后炎性色素沉着发生情况及其影响因素探讨_苏蕾.pdf
10.整形外科求美者体像障碍现状及与负性情绪的相关性研究_杨凯欣.pdf
11.A型肉毒毒素联合下睑皮肤入路法在松弛型眼袋修复中的应用效果_姜琰.pdf
12.颗粒脂肪联合纳米脂肪矫正重度鼻唇沟凹陷的临床研究_钟欣.pdf
13.基于多维评分系统的尿道下裂患儿术后并发症的风险预测模型的构建与验证_花鸣春.pdf
14.自拟活血通络方熏洗联合常规西药治疗糖尿病足溃疡的疗效观察_费驰媛.pdf
15.机器学习在骨性畸形横向特征识别中的应用研究_张吉利.pdf
16.下鼻甲体积和鼻中隔偏曲与颌面部发育的关系_刘佳.pdf
17.强脉冲光联合超脉冲二氧化碳点阵激光治疗面部皮肤光老化的临床效果-陈红方礼英吴岚英.pdf
18.强脉冲光联合超脉冲二氧化碳点阵激光预防面部外伤清创缝合术后早期瘢痕的临床疗效-闫美荣齐晓铭梁仁章张晓燕.pdf
7月8日创面修复
1.成人烧伤患者气道灌洗疗法专家共识（2026版）.pdf
2.足踝部复杂组织缺损的临床分型与显微重建策略.pdf
3.浅谈显微外科技术和游离穿支皮瓣修复创面.pdf
4.垂直褥式缝合联合水滴形动脉端侧吻合技术在游离皮瓣移植修复四肢创面中的临床应用效果.pdf
5.ALTF联合“Y”形大隐静脉移植修复小腿近中段大面积软组织缺损的临床效果.pdf
6.经真皮下入路切取旋髂浅动脉PSP皮瓣修复手足部皮肤软组织缺损的效果.pdf
7.大鼠骨髓间充质干细胞来源外泌体对高糖环境下大鼠Fb的影响及其机制.pdf
8.谷胱甘肽对小鼠皮肤急性光损伤的作用及其机制.pdf
9.大学生创伤后成长现状及其与创伤后应激症状之间的中介路径.pdf
10.线粒体动力学在糖尿病足溃疡中的作用机制及其相关干预策略研究进展.pdf
7月8日中华皮肤
1.抗p200类天疱疮诊断与治疗专家共识（2026版）.pdf
2.儿童肛门生殖器硬化性苔藓诊疗管理中国专家共识（2026版）.pdf
3.老年银屑病诊疗与康复专家共识（2026版）.pdf
4.毛发活检病理中国专家共识（2026版）.pdf
5.肠道菌群移植治疗银屑病专家共识（2026版）.pdf
6.反射式共聚焦显微镜联合皮肤镜对基底细胞癌的诊断价值评估.pdf
7.基于网络药理学与HaCaT细胞实验探讨茯苓及其活性成分茯苓酸对特应性皮炎相关炎症反应的作用及机制研究.pdf
8.经典型Ehlers-Danlos综合征1例COL5A1基因突变分析.pdf
9.乌帕替尼治疗6例掌跖脓疱病的临床疗效与安全性分析.pdf
10.度普利尤单抗治疗5例难治性内源性角化型手足部湿疹病例系列研究.pdf
11.家系环纹发1例.pdf
12.阿达木单抗治疗难治性青斑样血管病2例.pdf
13.新生儿吸吮性水疱1例.pdf
14.生物制剂治疗银屑病与特应性皮炎后出现免疫漂移：临床特征、机制与治疗策略.pdf
15.温泉疗法在皮肤病中的研究进展.pdf
7月8日中华整形
1.预扩张远位皮瓣在儿童上肢大面积皮肤缺损修复中的应用效果.pdf
2.高频彩色多普勒超声辅助设计带感觉神经的游离分叶股前外侧穿支皮瓣修复手足复杂创面.pdf
3._锚钉_式腱骨重建治疗指伸肌腱止点撕脱伤的效果观察.pdf
4.M形接力皮瓣修复儿童手指屈曲畸形松解后皮肤缺损的临床效果.pdf
5.游离股前外侧皮瓣修复手部严重瘢痕挛缩畸形效果观察.pdf
6.躯体变形障碍在鼻整形求美者与非鼻整形人群中的对比：一项横断面研究.pdf
7.耳部自体组织移植在后天性耳廓部分缺损修复中的临床应用.pdf
8.聚左旋乳酸注射填充治疗鼻唇沟凹陷的安全性及有效性研究.pdf
9.人参皂苷Rg3经IGF2BP2_HK2轴调控糖代谢抑制皮肤鳞状细胞癌机制研究.pdf
10.瘢痕疙瘩体外模型研究现状.pdf
11.皮肤下软组织扩张器的应用.pdf
12.昼夜节律紊乱与难愈性创面：聚焦皮肤屏障功能和免疫稳态.pdf
13.中药在增生性瘢痕治疗中的研究进展.pdf
14.Pierre-Robin综合征患儿吞咽障碍的康复评估与干预进展.pdf
15.围手术期加速康复外科理念在无水乙醇治疗头颈部动静脉畸形中的应用进展.pdf
2026-06-30
此部分内容仅为学习群每日更新的医美类文献名称汇总，文献为机翻仅供参考。我们会每周从国内外期刊上查找医美类或有一定关系的文献。供大家参考。方便学习群群友无法通过学习群查询到文献后通过公众号查询到相关文章。根据热度也可能做一些产品汇总文献。由于精力有限肯定存在错误，仅供参考。所有文献版权归属出版机构，汇总名称仅为方便从业人员了解（每日文献多数为出版社最近出版或更新的文献。）
6月30日
1.Pilot Study: Repeated Utenpanium (RZL-012) Treatment for Submental Fat Reduction
2.Breed-specific Risk Factors and Clinical Outcomes in Pediatric Dog Bite Injuries: A 14-year Retrospective Analysis
3.Comparative Analysis of Electrocautery Versus LigaSure Energy-based Device for Anterolateral Thigh Free Flap Dissection
4.Effect of Prior Abdominal Surgery on Abdominal-based Free-flap Breast Reconstruction Outcomes: A Systematic Review and Meta-analysis
5.Unveiling Sunderland Zero Injury in a Patient with Brachial Plexus Trauma
6.A Novel Classification of the Modified Cross-finger Flap for the Repair of Fingertip Defects
7.Plant Exosome Injection with or without Low Level Laser Therapy Promotes Skin Wound Healing: An Experimental Study
8.Postoperative Outcomes of Absorbable versus Nonabsorbable Sutures in Trigger Finger Release Closure: A Systematic Review and Meta-analysis
9.Rib Grafts in Rhinoplasty: A Systematic Review and Meta-analysis of Autologous, Fresh-frozen, and Irradiated Cartilage
10.Porous Architecture and Pressure-Induced Latent Injury: New Insights into Large-Volume Fat Grafting
11.Global Insights Into Confidence and Self-Perception in Aesthetic Medicine: A 15-Country Survey Analysis更正
12.Anatomical Variations and Surgical Implications of the Cervical Branch of the Facial Nerve: A Systematic Review
13.Uniform Treatment Protocol With Hybrid-SVF and Platelet-Rich Plasma on Micro-Fat Grafting With Face Lifting: A Preliminary Retrospective 3D Vectra Observational Study
14.Circumferential Lower Body Lift With Superficial Fascial System Preservation in Patients With BMI Below 30: A Standardized Technique and Retrospective Analysis of 110 Patients
15.Long-Term Treatment With Juvéderm Hyaluronic Acid Injectables for ≥ 10 Years: Expert Considerations for Natural Outcomes
16.Exploring the Efficacy and Safety of Topical Phenytoin in Androgenetic Alopecia: A Clinical Investigation
17.Patient satisfaction and complication profile following deep plane facelift: a retrospective analysis using the FACE-Q
18.Comparative analysis of two-stage versus three-stage paramedian forehead flap for nasal reconstruction: a systematic review and meta-analysis
19.Effectiveness of Intralesional Tranexamic Acid Versus Platelet-Rich Plasma in Melasma: A Systematic Review and Meta-Analysis
20.Evaluation of CGRP Levels in Patients With Rosacea: A Prospective Case–Control Study
21.Association Between Circulating Androgens and Androgenetic Alopecia in Adult Males: A Systematic Review
22.Short-Term Cardiac and Metabolic Safety of Propranolol Therapy in Infants With Infantile Hemangiomas: A Retrospective Real-World Study
23.High-Dose Baricitinib for Severe Alopecia Areata with Suboptimal Response to Conventional Therapy: A Real-World Assessment
24.Selective Modulation of Cutibacterium acnes Biofilms in Acne: Limitations of Conventional Therapies and Emerging Anti-Virulence Strategies
25.JAK inhibitor–associated acne: a mechanistic paradox with important clinical implications
26.Acute-phase Disease and Super-responder Status Predict Reduced Relapse Risk After Ritlecitinib Withdrawal in Alopecia Areata: A Prospective Real-World Study
27.Ultrasound-Guided Hyaluronidase Administration with Remote Expert Guidance for Vascular Adverse Events after Filler Treatment
28.Protective Effects of Antioxidant Chaga Mushroom Decoction on Normal Human Dermal Fibroblasts Exposed to UV-A
29.Systematic Optimization of Transfer Learning for Acne Severity Classification Using Restricted, Imbalanced and Non-Public Facial Images: An Experimental Study
30.Cannabidiol-Loaded Hyaluronic Acid-Based Nanogel for Inflammatory Acne: In Vitro and Open-Label, Non-Randomized Clinical Evaluation of Efficacy and Tolerability
31.Successful Revision Surgery After Postsurgical Pyoderma Gangrenosum Following Reduction Mammaplasty: A Case Report
32.Associations between lifestyle, clinical factors, phenotypes and symptoms of rosacea: a cross-sectional case–control study
33.Efficacy of Intralesional Bevacizumab Versus Intralesional Triamcinolone Acetonide Injection in the Treatment of Keloids: A Randomized Clinical Trial
34.Icariin Regulates Acne Pathophysiology and Extracellular Matrix Protein Synthesis: Implications for Acne Vulgaris and Atrophic Acne Scar Management
35.Targeting Neurovascular Inflammation in Rosacea: A Systematic Review of Botulinum Toxin Therapy
36.Success of Deuruxolitinib (Leqselvi™) in Extensively Treatment-Resistant Alopecia Universalis: A Case Report
37.Novel Combination Scalp Therapy for Androgenetic Alopecia: A Preliminary Retrospective Case Series with an Illustrative Four-Year Case
38.Effects of GLP-1 Receptor Agonists on Breast Reconstruction Outcomes: A Large-Database Retrospective Study
39.Residual CSB activity explains mild UV-sensitive syndrome phenotype caused by CSB mutations
40.Topical Recombinant Collagen Following Fractional Radio Frequency Microneedling for Nonsurgical Facelift: Case Report
1. 重复Utenpanium（RZL-012）治疗减少颏下脂肪的试点研究
2. 儿童犬咬伤的品种特异性危险因素与临床结局：14年回顾性分析
3. 电凝与LigaSure能量器械用于股前外侧游离皮瓣切取的对比分析
4. 既往腹部手术对腹部供区游离皮瓣乳房重建结局的影响：系统评价与Meta分析
5. 臂丛神经外伤患者中发现桑德兰0度损伤
6. 改良邻指皮瓣修复指端缺损的新型分型
7. 植物外泌体注射联合或不联合低强度激光治疗促进皮肤创面愈合：实验研究
8. 可吸收与不可吸收缝线用于扳机指松解术切口闭合的术后结局：系统评价与Meta分析
9. 鼻整形术中肋软骨移植物：自体、新鲜冰冻与辐照软骨的系统评价与Meta分析
10. 多孔结构与压力诱导隐匿性损伤：大容量脂肪移植的新见解
11. 全球医疗美容领域自信与自我认知洞察：15国调查分析（更正）
12. 面神经颈支的解剖变异及其手术意义：系统评价
13. 混合基质血管组分联合富血小板血浆用于面部提升联合微脂肪移植的标准化方案：基于3D Vectra的初步回顾性观察研究
14. BMI＜30患者保留浅筋膜系统的环周下半身提升术：标准化术式及110例患者回顾性分析
15. Juvéderm透明质酸注射剂≥10年长期治疗：实现自然效果的专家考量
16. 外用苯妥英治疗雄激素性脱发的疗效与安全性探索：临床研究
17. 深层平面面部提升术后患者满意度与并发症谱：基于FACE-Q的回顾性分析
18. 二期与三期额旁正中皮瓣用于鼻重建的对比分析：系统评价与Meta分析
19. 皮损内注射氨甲环酸与富血小板血浆治疗黄褐斑的疗效比较：系统评价与Meta分析
20. 玫瑰痤疮患者降钙素基因相关肽水平评估：前瞻性病例对照研究
21. 成年男性循环雄激素与雄激素性脱发的相关性：系统评价
22. 普萘洛尔治疗婴儿血管瘤的短期心脏与代谢安全性：回顾性真实世界研究
23. 高剂量巴瑞替尼治疗常规治疗应答不佳的重度斑秃：真实世界评估
24. 痤疮中痤疮丙酸杆菌生物膜的选择性调控：传统治疗的局限与新兴抗毒力策略
25. JAK抑制剂相关痤疮：具有重要临床意义的机制悖论
26. 急性期疾病状态与超应答状态可预测斑秃患者停用利特昔替尼后复发风险降低：前瞻性真实世界研究
27. 远程专家指导下超声引导注射透明质酸酶处理填充剂术后血管不良事件
28. 抗氧化白桦茸水煎剂对UVA照射后人正常真皮成纤维细胞的保护作用
29. 基于受限、非均衡非公开面部图像的痤疮严重程度分类迁移学习系统优化：实验研究
30. 负载大麻二酚的透明质酸基纳米凝胶治疗炎症性痤疮：体外及开放标签非随机临床疗效与耐受性评估
31. 乳房缩小术后坏疽性脓皮病的成功翻修手术：病例报告
32. 玫瑰痤疮的生活方式、临床因素、表型与症状的相关性：横断面病例对照研究
33. 皮损内注射贝伐珠单抗与曲安奈德治疗瘢痕疙瘩的疗效对比：随机临床试验
34. 淫羊藿苷调控痤疮病理生理与细胞外基质蛋白合成：对寻常痤疮及萎缩性痤疮瘢痕管理的启示
35. 靶向玫瑰痤疮神经血管炎症：肉毒毒素治疗的系统评价
36. Deuruxolitinib（Leqselvi™）治疗多重难治性全秃有效：病例报告
37. 新型头皮联合疗法治疗雄激素性脱发：初步回顾性病例系列及4年典型病例
38. GLP-1受体激动剂对乳房重建结局的影响：大型数据库回顾性研究
39. 残余CSB活性可解释CSB突变所致轻型紫外线敏感综合征的表型
40. 点阵射频微针术后外用重组胶原蛋白实现非手术面部提升：病例报告
文献求助
1.Beyond Flap Survival: Aesthetic Satisfaction and Patient-Reported Outcomes in Microsurgical Lower Limb Reconstruction
2.LigaSure-assisted Retaining Ligament Release during Composite Deep Plane Face and Neck Lift: A Three-Sign Structured Framework
3.Wise Pattern Skin-Sparing Mastectomy with Two-Stage Implant-Based Breast Reconstruction Among Patients with Breast Ptosis
4.Prevention of Tendon Adhesion and Preservation of Healing Strength Using a Hydrophobically Modified Alaska Pollock Gelatin Sheet
5.Long-term efficacy of low-dose oral minoxidil for the treatment of scarring and non-scarring alopecias: a one-year retrospective study（暂无）
6.Experimental Rat Peripheral Nerve Models: Surgical Exposures and Applications.
7.Gram-Negative Bacteria and Salvage Rate in Infected Breast Implants（暂无）
8.Optimal Timing for Expander to Implant Exchange After Postmastectomy Radiation Therapy（暂无）
9.Vascular Anomalies: A Comprehensive Review of Etiology, Complications, and Management Strategies.
10.The Cost of Matching into Plastic Surgery.
11.Regarding “The Cost of Matching Into Plastic Surgery”（暂无）
12.Response to: The Cost of Matching into Plastic Surgery.
13.Evaluating the Efficacy and Safety of Venous Flow-Through Flaps in Hand Reconstructive Surgery: A Systematic Review.
6月29日
1.眼轮匝肌固位结构松解提升术结合皮肤入路眶隔重置睑袋的临床应用_何宸
2.睑缘切开皮瓣转位与Hotz法联合方案治疗上睑瘢痕性睑内翻的效果及对患者心理和生活质量的影响_丁倩倩
3.Bell氏现象与上睑下垂-杨超邢新
4.脱细胞异体真皮基质与人工真皮在功能部位创面修复中的临床应用研究_方强伟
5.“内入路法”在鼻整形手术中的应用效果_顾勤浩
6.自体耳软骨联合“柳叶”型假体搭建L型支架在鼻整形中的临床效果_薛云鹏
7.鼻唇部肌肉生物力学解剖及A型肉毒毒素注射动力平衡进展_邓哲
8.乳房假体包膜挛缩的防治策略：现状与挑战_杨艾雪
9.推进皮瓣修复睑黄瘤切除术后缺损同时行重睑成形术矫正上睑松弛二例_马天华
10.自体耳软骨移植联合局部肌皮瓣在下睑退缩功能性重建中的临床应用_乔嘉
11.眼轮匝肌切除术联合眼轮匝肌缩短下睑缩肌复位术治疗退行性下睑内翻的应用研究_程凤
12.扩展下睑整形术的新思路：睑袋整形联合埋线环抱提升前中面部脂肪垫在中面部年轻化中的应用_翟伟
13.内外联合切口在睑袋及泪沟畸形矫正中的应用_翟亮
6月29日
1.健运中焦法指导下穴位埋线联合限能膳食干预肝郁气滞型肥胖临床研究_侯丽丽
2.“埋没导引”内固定缝合技术在旋切刀治疗项背部脂肪垫中的应用_戚昌栋
3.积雪草苷预防皮瓣坏死相关机制的研究进展_曲芳汶
4.重睑联合睑缘灰线切开自体脂肪填充治疗上睑内翻倒睫的效果观察_闫丽娟
5.“Z”形切开法与“一”字形切开法矫正成人内眦赘皮的效果对比_韩晓东
6.Er_YAG激光辅助牙周翻瓣植骨术对重度牙周炎患者牙周附着水平及美学效果的影响_刘伟
7.腭中缝成熟度智能影像评估的研究进展_邓倩
8.前列腺素与脱发的相关性研究及治疗进展-周莹莹毛秋霞朱红柳高以红
9.美容清创缝合结合瘢痕早期干预治疗儿童颜面部皮肤软组织撕脱伤疗效观察_汪城河
10.基于微创的多维度、多模式、可持续的非手术面部年轻化_张秀丽
11.微切口埋线法联合Park“Z”成形术矫正内眦赘皮在重睑成形术中的应用_王红
12.当归苦参丸联合单极微针射频治疗面部湿热瘀阻型痤疮的临床疗效观察_谢红亮
13.假体联合自体脂肪移植在二期法乳房重建中的临床疗效及安全性分析_陈雨
14.国医大师凃晋文应用刺蒺藜治疗损容性皮肤病经验_张子琦
15.瘢痕疙瘩肿瘤相关性实验模型的研究进展及其技术策略-吕尚军白国玺曹锐范荣辉孙勇
16.应力促进BMMSCs迁移及Smad信号通路在其中的作用机制研究_韩妍冬
17.不同强度静磁场对人角质形成细胞、成纤维细胞及小鼠成纤维细胞生物学特性的影响_武娟
18.皮肤镜结合皮肤生理指标检测在3%十二烷基硫酸钠斑贴试验刺激反应中的应用_叶聪秀
19.低剂量异维A酸联合强脉冲光治疗青春期后痤疮_冯婷
20.自由穿支筋膜蒂皮瓣在躯干小范围脓肿创面修复中的应用_尹兆会
21.眶隔脂肪部分去除联合自体眶隔脂肪多层次填充泪沟在下睑部年轻化中的临床应用_王雪宜
22.清心消痤饮联合30%超分子水杨酸治疗青春期后女性痤疮的临床观察_王海瑞
23.532_nm激光与超脉冲点阵CO_2激光联合果酸治疗面部脂溢性角化病_张静娴
24.腔镜下溶脂吸脂术对男性乳房发育患者术后早期恢复及乳房外观的影响_魏飞鹏
25.烧伤患者血清细胞因子及淋巴细胞水平变化与烧伤程度和创面愈合的关系研究_胡冰
26.五瓣成形术治疗手指外伤后瘢痕挛缩屈曲畸形疗效观察_陈树涛
27.罗伊适应模式对面部良性肿瘤切除患者心理状态及术后恢复的影响_张莉
28.羟基磷灰石联合透明质酸钠凝胶在女性扩大耳廓颅耳角美容中的应用研究_吕佳忆
29.植皮术联合外用重组人粒细胞巨噬细胞集落刺激因子凝胶治疗Ⅲ度烧伤创面疗效观察_刘奇
30.黑素瘤细胞外泌体来源的环状RNA_circ＿0084043对淋巴管内皮细胞的调控作用及机制研究_赵旭明
6月28日
1.Use of fractional and microablative CO2 laser in cases of vulvar lichen sclerosus: a clinical-histological analysis
2.Effectiveness of low-level laser therapy compared to standard postoperative care on pain intensity and cesarean section wound healing in the immediate postoperative period: a randomized clinical trial
3.The Coronavirus Disease 2019 Impact on Plastic Surgery Training: A 9-year National Analysis of Case Log Disruptions and Recovery
4.Shaping the Future: A 9-year National Analysis of Aesthetic Surgery Training in Plastic Surgery Residency
5.Superselective Craniofacial Nerve Decompression in a Pediatric Patient: A Case Report
6.Standardized 6-minute Indocyanine Green Angiography in Equivocal Digital Perfusion: A Prospective Feasibility Study
7.Impact of COVID-19 Infection and Vaccination on Abdominal-based Microvascular Breast Reconstruction Outcomes
8.Comparative Outcomes of Deep Inferior Epigastric Perforator Flap and Breast Implants in Breast Reconstruction Postmastectomy: A Systematic Review and Meta-analysis
9.Modified Fillet Toe Flap for Toe Amputation: A Random-pattern Approach beyond the Axial Concept
10.Superiority of the Dutch Breast Implant Registry over electronic patient records in tracing breast implants: results of a test recall
11.Body composition as an indicator of the risk of complications after microvascular DIEP breast reconstruction
12.Revisiting the Deep Fatty and Fascial Layers Between the Temple and the Midface: An Ultrasound-based Investigation
13.Avoiding Litigation With the Use of Resorbable Breast Mesh: Practical Suggestions for Plastic Surgeons
14.Comparison of Histological Effects of LigaSure and Bipolar Cautery on the Submandibular Gland in a Rat Model
15.Five-year Patient-reported Outcomes Following Primary Breast Augmentation With Polyurethane-coated Implants: Development and Preliminary Validation of a Device-specific Instrument
16.Multimodal Approach for Lower Leg Liposculpture: A Case Series and Lessons Learned
17.Wound Dressing and Post-Operative Complications Following Breast Reduction: A Retrospective Study of 250 Patients
18.Enhancing pre-operative decision making in breast augmentation: navigating the role of 3d simulations
19.Evaluation of Parameters Determining the Pull-Out Strength of Poly(L-Lactide-Co-ϵ-Caprolactone) Barbed Suspension Threads: A Comparative ex vivo Study
20.Denifanstat in acne therapy: A promising step forward
21.A wake-up call for acne
22.Can a healthy plant-based diet lower the risk of rosacea development?
23.Dermatology Images: Congenital dermal melanocytosis
24.Correspondence to Abdel Azim, Sara et al. “Sunscreens part 2: Regulation and safety”. Regulatory Gaps in Sunscreen Approval: A Comparison of U.S. and Korean UV Filters
25.Response to Pak et al., “Regulatory Gaps in Sunscreen Approval: A Comparison of U.S. and Korean UV Filters.” Sunscreen Regulatory Update: Approval of Bemotrizinol by the US FDA
26.Evaluating Skin Tone Bias in Multimodal Large Language Models for Autoimmune and Immune-Mediated Skin Diseases
27.Navigating Patient Smartphone Use in the Dermatology Clinic
28.Formulating Glycolic Acid: Balancing Penetration, Irritation, and Therapeutic Outcomes in Dermatology
29.An Optimized Naturally Derived Formulation Extract Alleviates UV-Induced Skin Photoaging and Supports Topical Lotion and Cream Development
30.Factors Associated with Resection Weight and Complications after Massive-Weight-Loss Abdominoplasty: A Retrospective 10-Year Single-Center Study
31.The application of a simple and efficient negative suction system in two-staged microtia reconstruction
32.Immediate and Single-Stage Facial Reanimation After Radical Parotidectomy and Oncologic Facial Nerve Sacrifice: A Systematic Review
33.Complication rate after implant-based breast-reconstruction with support of a synthetic non-resorbable titanized polypropylene mesh (TiLOOP® Bra): Analysis of the 2-year follow up from the prospective multicentre PRO-BRA trial
34.Achilles Tendon Allograft Implantation for Anterior Axillary Fold Reconstruction in Poland Syndrome
35.Hyaluronidase and the language of filler reversal: why “dissolving filler” may be the wrong term
36.Cutaneous perforator mapping and ink-based perfusion assessment in an ovine model: an anatomical study and systematic review
37.Revisiting Guidelines for Global Plastic and Reconstructive Surgical Initiatives: Recommendations from a Scoping Review of Two Decades of Published Evidence
38.The Efficacy of Current Approaches to Non-invasive Diagnosis of Skin Cancer and the Potential Impact of Artificial Intelligence: A Systematic Review and Meta-Analysis
39.Increased risk of alopecia areata in patients with Down syndrome (trisomy 21): a multi-center analysis using TriNetX
40.Emerging concepts: regenerative medicine in dermatology
41.rs4541843 G > A variant near miR-182 is associated with susceptibility, severity, and increased hsa-miR-182-5p expression in alopecia areata
42.Botulinum Toxin in Parkinson’s Disease Tremor: A Critical Evaluation of the Evidence and Clinical Practice
43.Evaluation of Intralesional Bleomycin and Triamcinolone Acetonide in the Treatment of Keloids: A Prospective, Randomized, Open-Label, Comparative Study
44.Photo-Pollution Induced Activation of the Aryl Hydrocarbon Receptor Drives Oxidative Stress and Melanogenesis in Human Skin Models
45.Botulinum toxin A for the Treatment of Androgenetic Alopecia: A Review
46.Perioperative Protein and Vitamin Supplementation in Plastic Surgery: An Evidence-Based Proposal for an Assessment and Replacement Protocol
47.Successful Treatment of Nevus of Ota With a 694-nm Q-switched Ruby Laser: A Case Report
48.Influence of Social Media on Perceptions and Decision-Making Regarding Cosmetic Dermatologic Procedures Among Young Adults in Saudi Arabia: A Cross-Sectional Study
49.A Primate-Specific lncRNA LINC01021 Contributes to Cellular and Organismal Aging via DAZAP1-Dependent Destabilization of RBMX
50.The Rintala Advanced Modification (RAM) Flap: A Novel Technique for Off-Centre Nasal Reconstruction
51.Serological biomarkers of extracellular matrix proteins are associated with hidradenitis suppurativa disease severity and treatment response
52.Successful carbon dioxide laser ablation in acquired idiopathic vulval lymphangiectasia
53.Development and validation of the Maladaptive Eating Behavior Questionnaire after Metabolic and Bariatric Surgery
54.Individuals With Food Addiction After Metabolic And Bariatric Surgery Show Higher Consumption of Ultra-Processed Foods, Sedentary Lifestyle, Anxiety, and Sub-Optimal Body Weight Trajectories
55.National Trends and Outcomes of Metabolic and Bariatric Surgery in Adolescents: Insights from the Israeli National Bariatric Surgery Registry
56.Comparative Outcomes of GLP-1 Therapy vs. Bariatric Surgery in Patients with Cirrhosis
57.Pyramidal-Shaped Costal Cartilage Columellar Strut Graft with Half-Harvest Technique for Augmentation Rhinoplasty: A Novel Approach to Tip Mobility Preservation
58.Hyaluronic Acid Fillers Versus Polynucleotides for Under-Eye Rejuvenation
59.Comparative Real-World Outcomes of OnabotulinumtoxinA and CGRP Monoclonal Antibodies in Chronic Migraine
60.The Bacterial Landscape of Facial Skin: From Homeostasis to Skin Conditions
61.Do Fasting GLP-1 and GIP Levels Predict the Initial Pharmacological Response to Semaglutide and Tirzepatide?
62.Ultrasound-Guided Low-Dose Hyaluronidase for Infraorbital Artery Occlusion with Secondary Gingival Ischemia After Hyaluronic Acid Filler Injection: A Case Report
63.Randomised Controlled Feasibility Trial of an Intervention to Reduce Infant Bathing
1. 点阵微剥脱型二氧化碳激光在外阴硬化性苔藓中的应用：临床与组织学分析
2. 低强度激光治疗对比标准术后护理对剖宫产术后即刻疼痛程度与切口愈合的效果：一项随机临床试验
3. 2019冠状病毒病对整形外科培训的影响：基于全国9年手术日志中断与恢复情况的分析
4. 塑造未来：整形外科住院医师美容外科培训的全国9年数据分析
5. 儿科患者超选择性颅面神经减压术：病例报告
6. 标准化6分钟吲哚青绿血管造影用于临界指端灌注评估：一项前瞻性可行性研究
7. 新型冠状病毒感染与疫苗接种对基于腹部的微血管乳房重建结局的影响
8. 乳房切除术后腹壁下动脉穿支皮瓣与假体乳房重建的结局对比：系统评价与Meta分析
9. 改良趾端鱼际皮瓣用于趾部截肢：突破轴型理念的随意型皮瓣术式
10. 荷兰乳房假体登记系统在假体溯源方面优于电子病历：召回测试结果
11. 身体成分作为腹壁下动脉穿支皮瓣微血管乳房重建术后并发症风险的预测指标
12. 颞部至面中部深层脂肪与筋膜层次再探：一项基于超声的解剖学研究
13. 使用可吸收乳房补片规避医疗纠纷：给整形外科医师的实操建议
14. LigaSure与双极电凝对大鼠颌下腺组织学影响的对比研究
15. 聚氨酯涂层假体初次隆乳术后5年患者报告结局：器械专用评估工具的开发与初步验证
16. 小腿综合塑形吸脂术：病例系列与经验总结
17. 乳房缩小术后伤口敷料与术后并发症：250例患者回顾性研究
18. 优化隆乳术术前决策：3D模拟技术的应用路径探析
19. 聚(L-乳酸-co-ε-己内酯)倒钩悬吊线拔出强度的影响参数评估：离体对比研究
20. Denifanstat用于痤疮治疗：前景可期的重要进展
21. 痤疮领域的警示之声
22. 健康植物性饮食能否降低玫瑰痤疮发病风险？
23. 皮肤病学图像：先天性真皮黑素细胞增多症
24. 致Abdel Azim, Sara等人《防晒剂第二部分：监管与安全性》的通信：防晒剂审批的监管空白——美国与韩国紫外线防晒剂对比
25. 对Pak等人《防晒剂审批的监管空白：美国与韩国紫外线防晒剂对比》的回复：防晒剂监管最新进展——美国FDA批准Bemotrizinol
26. 自身免疫与免疫介导性皮肤病多模态大模型中的肤色偏倚评估
27. 皮肤科门诊中患者智能手机使用的应对与管理
28. 乙醇酸配方研发：平衡皮肤渗透性、刺激性与皮肤科治疗效果
29. 一种优化的天然来源配方提取物可缓解紫外线诱导的皮肤光老化，可用于外用乳液与面霜开发
30. 大幅减重后腹壁成形术切除组织重量与并发症的相关因素：单中心10年回顾性研究
31. 简易高效负压吸引系统在二期小耳畸形重建术中的应用
32. 腮腺根治性切除术联合面神经牺牲术后即刻单侧面瘫修复：系统评价
33. 合成不可吸收钛化聚丙烯补片（TiLOOP® Bra）辅助假体重建乳房的并发症发生率：PRO-BRA前瞻性多中心试验2年随访结果分析
34. 跟腱同种异体移植物植入重建波兰综合征前腋襞
35. 透明质酸酶与填充剂逆转的术语误区：为何“溶解填充剂”的表述并不准确
36. 绵羊模型皮肤穿支血管定位与墨水灌注评估：解剖学研究与系统评价
37. 全球整形外科与重建外科公益项目指南再修订：基于二十年已发表证据的范围审查建议
38. 现有皮肤癌无创诊断方法的效能与人工智能的潜在影响：系统评价与Meta分析
39. 唐氏综合征（21三体）患者斑秃风险升高：基于TriNetX的多中心分析
40. 前沿理念：皮肤病学中的再生医学
41. miR-182附近rs4541843 G>A变异与斑秃易感性、严重程度及hsa-miR-182-5p表达升高的相关性
42. 肉毒毒素治疗帕金森病震颤：证据与临床实践的批判性评价
43. 皮损内注射博来霉素与曲安奈德治疗瘢痕疙瘩的疗效评价：一项前瞻性、随机、开放标签对照研究
44. 光污染诱导芳香烃受体活化驱动人体皮肤模型氧化应激与黑素生成
45. A型肉毒毒素治疗雄激素性脱发：综述
46. 整形外科围手术期蛋白质与维生素补充：基于证据的评估与补充方案建议
47. 694nm Q开关红宝石激光成功治疗太田痣：病例报告
48. 社交媒体对沙特阿拉伯年轻人群美容皮肤科手术认知与决策的影响：一项横断面研究
49. 灵长类特异性长链非编码RNA LINC01021通过DAZAP1依赖途径降解RBMX，参与细胞与机体衰老过程
50. Rintala进阶改良（RAM）皮瓣：一种用于偏心位鼻部缺损重建的新技术
51. 细胞外基质蛋白血清生物标志物与化脓性汗腺炎疾病严重程度及治疗应答的相关性
52. 二氧化碳激光消融术成功治疗获得性特发性外阴淋巴管扩张症
53. 代谢减重术后适应不良进食行为问卷的开发与验证
54. 代谢减重术后食物成瘾患者摄入更多超加工食品、存在久坐生活方式、焦虑及体重控制效果不佳
55. 以色列全国减重手术登记数据：青少年代谢减重手术的全国趋势与结局
56. GLP-1治疗与减重手术在肝硬化患者中的结局对比
57. 半切取材法制备锥形肋软骨鼻小柱支撑移植物用于隆鼻术：保留鼻尖活动度的新术式
58. 透明质酸填充剂对比多核苷酸用于眼周年轻化治疗
59. OnabotulinumtoxinA与降钙素基因相关肽单克隆抗体治疗慢性偏头痛的真实世界疗效对比
60. 面部皮肤菌群图谱：从稳态到皮肤疾病
61. 空腹GLP-1与GIP水平能否预测司美格鲁肽与替尔泊肽的初始药物应答？
62. 超声引导下小剂量透明质酸酶治疗透明质酸填充剂注射后眶下动脉栓塞继发牙龈缺血：病例报告
63. 减少婴儿沐浴频次干预措施的随机对照可行性试验
文献求助
1.Lip Adhesion in the Wide Cleft Lip: Indications and Operative Technique
2.Emergence Point of the Zygomaticotemporal Nerve Relative to the Marginal Tubercle of the Zygomatic bone: a Cadaveric Study with Clinical Implications
3.Reconstruction of a Defect Involving the Upper Lip, Alar Base, and Medial Cheek
4.Frozen Section Biopsy as a Real-Time Decision-Support Tool in Dermatologic Surgery: A Retrospective Review
5.Pulsed-dye laser therapy for successful management of refractory neurogenic rosacea
6.From Innovation to Integration: Responsible Integration of Artificial Intelligence in Plastic Surgery.
7.Inferior Gluteal Myocutaneous Crescent V-Y Pendulum Flap for Closure of Ischial Pressure Sores: A Case Series.
8.Comparative Evaluation of ChatGPT-5.4 Mini and Gemini 3 Flash in Scar Patient Education: Quality, Reliability, and Readability Analysis
1. 宽裂隙型唇裂的唇粘连术：适应证与手术技巧
2. 颧颞神经穿出点与颧骨缘结节的位置关系：尸体解剖研究及临床意义
3. 累及上唇、鼻翼基底及颊内侧的缺损修复术
4. 冰冻切片活检作为皮肤外科实时决策辅助工具：回顾性研究
5. 脉冲染料激光成功治疗难治性神经源性玫瑰痤疮
6. 从创新到融合：人工智能在整形外科的负责任落地应用
7. 臀下肌皮新月形V-Y摆动皮瓣修复坐骨压疮：病例系列
8. ChatGPT-5.4 Mini与Gemini 3 Flash在瘢痕患者宣教中的对比评价：质量、可靠性与可读性分析
6月27日
1.Effect of Capacitive and Resistive electric transfer on haemoglobin saturation and tissue temperature
2.The influence of social media and easily accessible online information on the aesthetic plastic surgery practice: literature review and our own experience
3.Tissue-Engineered Soft-Tissue Reconstruction Using Noninvasive Mechanical Preconditioning and a Shelf-Ready Allograft Adipose Matrix
4.2Tissue-Engineered Soft-Tissue Reconstruction Using Noninvasive Mechanical Preconditioning and a Shelf-Ready Allograft Adipose Matrix
5.A multi-center, open-label, pilot study of allograft adipose matrix for the correction of atrophic temples
6.Hydrogel from Acellular Porcine Adipose Tissue Accelerates Wound Healing by Inducing Intradermal Adipocyte Regeneration
1. 电容电阻式电传输技术对血红蛋白饱和度与组织温度的影响
2. 社交媒体与便捷获取的网络信息对美容整形外科临床实践的影响：文献综述及本中心经验
3. 采用无创机械预处理与即用型同种异体脂肪基质的组织工程软组织重建
4. 采用无创机械预处理与即用型同种异体脂肪基质的组织工程软组织重建
5. 同种异体脂肪基质矫正颞部凹陷的多中心开放标签初步研究
6. 脱细胞猪脂肪组织来源水凝胶通过诱导真皮内脂肪细胞再生加速创面愈合
6月25日
1.Laser treatment of hypertrophic scars: the operative and peri-operative practices of burns clinicians
2.Comparing fractional CO₂ laser and needling-based modalities in facial acne scar treatment: a comprehensive systematic review and meta-analysis
3.Risk Factors for Free Flap Failure in Head and Neck Reconstruction: A Retrospective Analysis From a Single Medical Center
4.Efficacy and Safety of a Novel Sodium Hyaluronate Composite Solution via Mesotherapy for Facial Rejuvenation: A Multicenter Randomized Controlled Study
5.Battle of the Brands: A Multicenter Comparative Analysis of Outcomes in Immediate Implant-based Breast Reconstruction With Acellular Dermal Matrices
6.Statistical Reporting in Plastic Surgery Research
7.Two-step Xenogeneic Dermal Matrix-assisted Autologous Skin Grafting for Large Scalp Cutaneous Squamous Cell Carcinoma Ulcer
8.Local Injections of Fluorouracil for Eyelid Hordeolum
9.Pilot Study: DermiSphere: A Novel Hydrogel with Collagen Microspheres Dermal Regeneration Template
10.Predictors of Matching into Plastic Surgery Residency Integrated and Independent Tracks: A Systematic Review
11.Algorithm for Surgical Management of Symptomatic Hand and Digital Neuromas
12.Ultrasound in Gluteal Fat Grafting: Safety Tool, Standard of Care, or Emerging Evidence?: A Scoping Review
13.Venous Drainage and Nipple-Areolar Complex Necrosis After Nipple-Sparing Mastectomy: A Cadaveric and Prospective Clinical Cohort Study
14.Becker Expander Versus Fixed-volume Breast Implant: A Single Surgeon Multicenter Evaluation of Becker Expander and Literary Review
15.Do Textured Breast Implants Mitigate Malposition? A Systematic Review and Metanalysis
16.All About Clonidine and its Role in Preventing Hematoma Following Aesthetic Facial Surgery: A Narrative Review With Practical Guidance
17.The Impact of Artificial Intelligence on Facial Aesthetic Surgery: A Systematic Review
18.Peristaltic Pump–Assisted Fat Harvesting and Closed-Circuit Grafting: Technique and Immediate Cell Membrane Integrity in a Case Series
19.Association Between Proton Pump Inhibitor Use and Short-Term Postoperative Complications Following Abdominoplasty: A Multi-Institutional Cohort Study
20.Augmentation Mastopexy With Polyurethane-Coated Implants in the Prepectoral Plane: A 24-Month Follow-Up Study
21.Beyond PRP: Recognizing the Evolving Generations of Platelet Concentrates in Androgenetic Alopecia Treatment—A Letter in Response to Zhong Et al
22.Validation of the SkinConnect Nomadic Multi-Parametric Device for Assessing Stratum Corneum Hydration
23.Comparison of 1064-nm Picosecond and Q-Switched Neodymium-Doped Yttrium Aluminum Garnet Lasers for Melasma in Asian Women: A Randomized Double-Blind Split-Face Trial
24.Ashwagandha Root Extract and Its Potential Modulation of CCN1-Associated Pathways in Sensitive-Skin Aging
25.Efficacy and Safety of Supramolecular Salicylic Acid Combined With Intense Pulsed Light for Rosacea: A Split-Face Trial
Meifang Wang, Ansheng Tan, Fenglin Zhuo
26.Global analysis and latest research hot spots of skin grafting: A bibliometric analysis and visualized review
27.Unveiling the digital aesthetic: association between social media use and interest in cosmetic procedures among adult residents of Riyadh, Saudi Arabia: a cross-sectional study
28.Letter to the Editor: Critical Methodological Limitations in the Prospective Study of Fractional CO2 Laser Treatment for Female Vaginal Relaxation Syndrome
29.Optimized the Removal Technique for Double-Armed Sutures
30.Long-Term Comparative Effectiveness and Safety of Oral Versus Topical Tranexamic Acid for Melasma: A 24-Month Single-Center Retrospective Cohort Study (2020–2024)
31.Cutaneous Photoaging: A Review of Melasma and Nanotechnological Approaches to Its Control
32.Autologous Platelet Concentrates for the Treatment of Primary Cicatricial Alopecia: A Systematic Review
33.A Preliminary Study of Polycaprolactone Filler After Hyaluronidase for Facial Overfilled Syndrome
34.Successful Treatment of Extensive Ritlecitinib-Refractory Alopecia Areata with Upadacitinib
35.Exosomes-based biomarkers in precision dermatology: Priorities for translational development
36.Mantis flap for reconstruction of large full-thickness lower lip defects
37.Text-dominant decision-making by large multimodal models in dermatology clinical challenges. Comment on “AI-assisted dermatologic diagnosis using a large language model
38.Improved Detection of Lentigo Maligna with AI-Assisted Dermoscopy: A Reader Study in Facial Pigmented Lesions
39.Extended East-to-West Advancement Flaps for Large Defects of the Lower Face and Cervical Junction
40.Balancing Access and Experience: The Ethics of Clinic Overbooking
41.Liquid Extract from the Bark of Magnolia officinalis Rejuvenates Skin Aging Through Mitochondrial ROS Reduction已更正
42.Two-Stage Bone Grafting for Nasal Correction in Late-Presenting Patients with Unilateral Cleft: A 3-Year Comparative Study
43.Severity of deformational plagiocephaly: the role of Wormian and Inca bones
44.Experience with Tirzepatide and Weight Management During and After a Clinical Trial in Japanese Patients with Obesity Disease: A Qualitative Study
45.Treating Severe Obesity: A Medical Perspective
46.Two Toxins, One Disorder: Neurophysiological and Clinical Effects in Caput-Type of Cervical Dystonia at Waning and Peak Response Phases of BoNT-A Therapy
47.Effects of Botulinum Toxin Type A in Essential Blepharospasm: Evidence from a Clinical and Neurophysiological Pilot Study
48.Reprogramming macrophage mechanosensation via TRPV4 modulating mechano-immunotherapy controls fibrotic encapsulation of biomaterial implants
49.Enhancing scar appearance: Results from a cosmetic clinical study on dexpanthenol-containing silicone gel and massage ball in adults and children
50.The harnessing potential of carboxymethyl beta glucan: A driver of skin repair
51.Bakuchiol: From structural mimicry to systems-level skin biology
52.Synergistic enhancement SPF from annatto seed oil and alkaline extracts in association with organic UV filters
53.In Vivo Wound Healing Effects of Antimicrobial Peptide-Based Dressings for S. aureus-Infected Wounds—A Systematic Review and Meta-Analysis
54.Literature Review of Long-Term Sequelae and Modern Management of Infantile Hemangioma
55.Use of a Serum With the Infinite Glow® Device Improves Signs of Facial Aging: A Split-Face Case Report Using VISIA Analysis
56.Preclinical Histologic and Morphometric Comparison of Poly-L-Lactic Acid Fillers Formulated With Carboxymethyl Cellulose or Non-crosslinked Hyaluronic Acid in a Porcine Model
57.Facial Adipostructuring With Biochemical Modulation in Chronic Peripheral Facial Paralysis: A Case Report
58.An Aging Clock Based on Immune Repertoire Features: COVID-19 Accelerates Aging
59.Cellular Heterogeneity During Arterial Aging
60.Acne-related quality of life among adolescents and adults: a cross-sectional study in Antananarivo, Madagascar
61.Weight Loss, Comorbidity, and Complications After Single-anastomosis Sleeve Ileal Bypass (SASI): A Systematic Review and Meta-analysis
62.Standardized Pre- and Early Postoperative Dietary Protocols After Bariatric and Metabolic Surgery: A 20-Year Single-Center Experience Across Roux-en-Y Gastric Bypass, Sleeve Gastrectomy, and Ileal Procedures
63.Real-world clinical evaluation of Zymalge® gel for optimizing wound bed prior to skin grafting or spontaneous healing: a retrospective single-arm cohort study
64.The Absent Original in Smartphone Photography
65.The Absent Original in Smartphone Photography—Reply
66.Effectiveness of Botulinum Toxin Type A for Trichodynia Associated with Hair Loss Disorders: A Retrospective Study
67.Clinical efficacy and predictive factors of photodynamic therapy combined with recombinant mussel mucin repair dressing in treating post-inflammatory hyperpigmentation更正
68.Identification of Fibulin-5 as a Granzyme B Substrate Involved in UVB-Induced Elastic Fiber Disruption
69.A Multi-Centre Real-World Evaluation of Ritlecitinib in Severe Alopecia Areata: Early Real World Experience in a British Cohort
70.Outcome measure instruments for the assessment and treatment of androgenetic alopecia: A scoping review
71.From Clinical Practice to Basic Science, in Search for the Ideal Implantable Bioreactor: A Review on MFAT (Micro-Fragmented Adipose Tissue—Lipogems®) Biology and Its Clinical Applications
72.Exploring the Lived Experience of Acne in the United States and the United Kingdom: Social Media Analysis
73.Substrate Stiffness and Viscoelasticity Influence Fibroblast Senescence
74.Filler im Gesichtsbereich: Evidenzlage, anatomische Grundlagen, Materialien, Risiken, Techniken und zukünftige Entwicklungen
1. 增生性瘢痕的激光治疗：烧伤科临床医师的手术及围手术期操作实践
2. 点阵二氧化碳激光与微针类方案治疗面部痤疮瘢痕的对比：一项全面系统综述与荟萃分析
3. 头颈部重建中游离皮瓣失败的危险因素：单中心回顾性分析
4. 新型透明质酸钠复合溶液中胚层疗法用于面部年轻化的疗效与安全性：一项多中心随机对照研究
5. 品牌之争：即刻假体联合脱细胞真皮基质乳房重建疗效的多中心对比分析
6. 整形外科研究中的统计学报告现状
7. 两步法异种真皮基质辅助自体皮片移植治疗头皮大面积鳞状细胞癌溃疡
8. 氟尿嘧啶局部注射治疗眼睑麦粒肿
9. 初步研究：DermiSphere——一种含胶原微球的新型水凝胶真皮再生模板
10. 匹配整形外科一体化与独立路径住院医师规范化培训的预测因素：一项系统综述
11. 症状性手部与指部神经瘤的外科治疗算法
12. 超声在臀部脂肪移植中的应用：安全工具、诊疗标准还是新兴证据？——一项范围综述
13. 保留乳头乳房切除术后静脉回流与乳头乳晕复合体坏死：一项尸体解剖及前瞻性临床队列研究
14. Becker扩张器与固定容积乳房假体的对比：单术者多中心Becker扩张器疗效评估及文献综述
15. 毛面乳房假体是否可降低假体移位风险？一项系统综述与荟萃分析
16. 可乐定全面解析及其在面部美容术后血肿预防中的作用：附实操指导的叙述性综述
17. 人工智能对面部美容外科的影响：一项系统综述
18. 蠕动泵辅助脂肪获取与闭环移植技术：病例系列中的操作方法及即时细胞膜完整性评估
19. 质子泵抑制剂使用与腹壁成形术后短期并发症的相关性：一项多机构队列研究
20. 胸大肌前平面置入聚氨酯涂层假体行隆乳联合乳房上提术：一项24个月随访研究
21. 超越富血小板血浆：认识雄激素性脱发治疗中血小板浓缩物的代际演进——致Zhong等人的回应信
22. SkinConnect便携式多参数设备评估角质层水合度的验证研究
23. 1064nm皮秒与调Q掺钕钇铝石榴石激光治疗亚洲女性黄褐斑的对比：一项随机双盲半脸对照试验
24. 南非醉茄根提取物及其对敏感肌衰老中CCN1相关通路的潜在调控作用
25. 超分子水杨酸联合强脉冲光治疗玫瑰痤疮的疗效与安全性：一项半脸对照试验
26. 皮肤移植的全球研究现状与最新热点：一项文献计量分析与可视化综述
27. 数字审美揭秘：沙特阿拉伯利雅得成年居民社交媒体使用与美容手术意愿的关联：一项横断面研究
28. 致编辑的信：点阵二氧化碳激光治疗女性阴道松弛综合征前瞻性研究的关键方法学局限
29. 双针缝线的优化拆除技术
30. 口服与外用氨甲环酸治疗黄褐斑的长期疗效与安全性对比：一项为期24个月的单中心回顾性队列研究（2020–2024）
31. 皮肤光老化：黄褐斑概述及纳米技术调控策略综述
32. 自体血小板浓缩物治疗原发性瘢痕性脱发：一项系统综述
33. 透明质酸酶处理后使用聚己内酯填充剂改善面部过度填充综合征的初步研究
34. 乌帕替尼成功治疗广泛型利特昔替尼难治性斑秃
35. 精准皮肤病学中外泌体生物标志物的转化开发优先级
36. 螳螂皮瓣修复下唇大面积全层缺损
37. 多模态大模型在皮肤科临床挑战中以文本为主的决策模式——评《基于大语言模型的AI辅助皮肤病诊断》
38. AI辅助皮肤镜提升恶性雀斑样痣检出率：面部色素性病变的阅片者研究
39. 扩展型东-西向推进皮瓣修复面下部及颈颌交界区大面积缺损
40. 平衡可及性与就诊体验：诊所超额预约的伦理思考
41. 厚朴树皮液态提取物通过减少线粒体活性氧延缓皮肤衰老（已更正）
42. 二期植骨术矫正迟发性单侧唇裂患者鼻部畸形：一项为期3年的对比研究
43. 变形性扁头畸形的严重程度：缝间骨与印加骨的作用
44. 日本肥胖病患者临床试验期间及赛后替尔泊肽减重管理的体验：一项定性研究
45. 重度肥胖的治疗：内科视角
46. 两种毒素，一种疾病：A型肉毒毒素疗效消退与峰值阶段，头型颈肌张力障碍的神经生理学与临床效应
47. A型肉毒毒素治疗特发性眼睑痉挛的疗效：一项临床与神经生理学初步研究证据
48. 通过TRPV4重编程巨噬细胞机械感知调控机械免疫治疗，可抑制生物材料植入物的纤维化包裹
49. 改善瘢痕外观：含泛醇的硅酮凝胶配合按摩球用于成人与儿童的美容临床研究结果
50. 羧甲基β-葡聚糖的应用潜力：皮肤修复的驱动因素
51. 补骨脂酚：从结构模拟到系统层面的皮肤生物学作用
52. 胭脂树籽油与碱性提取物联合有机紫外线过滤剂的防晒系数协同增强效应
53. 抗菌肽类敷料对金黄色葡萄球菌感染创面的体内促愈合作用——一项系统综述与荟萃分析
54. 婴幼儿血管瘤远期后遗症与现代治疗进展的文献综述
55. 精华液联合Infinite Glow®设备改善面部衰老征象：一项采用VISIA分析的半脸病例报告
56. 猪模型中含羧甲基纤维素与非交联透明质酸的聚左旋乳酸填充剂的临床前组织学与形态计量学对比
57. 慢性周围性面瘫患者采用生化调节的面部脂肪结构重塑：一例病例报告
58. 基于免疫组库特征的衰老时钟：新型冠状病毒肺炎加速衰老进程
59. 动脉衰老过程中的细胞异质性
60. 青少年与成人痤疮相关生活质量：马达加斯加塔那那利佛的一项横断面研究
61. 单吻合口袖状回肠旁路术后体重下降、合并症与并发症：一项系统综述与荟萃分析
62. 减重与代谢手术前后标准化早期饮食方案：单中心20年经验，涵盖Roux-en-Y胃旁路术、袖状胃切除术及回肠术式
63. Zymalge®凝胶用于皮片移植或自然愈合前优化创面床的真实世界临床评价：一项回顾性单臂队列研究
64. 智能手机摄影中的原作缺失
65. 《智能手机摄影中的原作缺失》——回复
66. A型肉毒毒素治疗脱发相关毛痛的疗效：一项回顾性研究
67. 光动力疗法联合重组贻贝黏蛋白修复敷料治疗炎症后色素沉着的临床疗效及预测因素（更正）
68. 证实Fibulin-5是颗粒酶B的底物，参与UVB诱导的弹性纤维断裂
69. 利特昔替尼治疗重度斑秃的多中心真实世界评价：英国队列的早期真实世界经验
70. 雄激素性脱发评估与治疗的结局测量工具：一项范围综述
71. 从临床实践到基础科学，探寻理想的植入式生物反应器：MFAT（微碎片化脂肪组织——Lipogems®）生物学及其临床应用综述
72. 美国与英国痤疮患者的真实体验探究：社交媒体分析
73. 基质硬度与黏弹性影响成纤维细胞衰老
74. 面部填充剂：循证基础、解剖学原理、材料、风险、技术及未来发展
文献求助
1.Cleft Palate Repair Guided by Cleft Gap: An Institutional Protocol Using Modified Asymmetric Short Limb Z-plasty (MASLZ) and Straight-line Repair
2.Periprocedural Cooling During Botulinum Toxin Injection: Surface Temperature Effects and Practical Clinical Considerations
3.Endovenous Laser Ablation of Supratrochlear Forehead Veins: 10-Year Experience
4.Commentary on “A Calculator for Maximal Local Anesthetic Doses in Dermatologic Surgery”
5.Repair of a Large Multi-subunit Lower Eyelid and Cheek Defect
6.An injectable microsphere-reinforced system for sustained delivery of Adipo-MBV in adipose tissue engineering
7.Unraveling and Harnessing the Immune Response at the Cell–Biomaterial Interface for Tissue Engineering Purposes
8.Biocompatibility Evolves： Phenomenology to Toxicology to Regeneration
9.Key players in the immune response to biomaterial scaffolds for regenerative medicine
1. 基于裂隙间距指导的腭裂修复：采用改良不对称短臂Z成形术（MASLZ）与直线修复的单中心操作方案
2. 肉毒毒素注射围操作期降温干预：体表温度影响及临床实操注意事项
3. 额部滑车上静脉的静脉内激光消融治疗：10年临床经验
4. 评《皮肤外科局部麻醉药最大剂量计算器》
5. 下睑与颊部多亚单位大面积缺损的修复
6. 一种用于脂肪组织工程中Adipo-MBV缓释递送的可注射微球强化体系
7. 组织工程应用中细胞-生物材料界面免疫应答的解析与调控
8. 生物相容性的演进：从现象学到毒理学再到再生
9. 再生医学生物材料支架免疫应答中的关键调控因子
6月23日
1.Comment on “AI-Based Quantitative and Objective Analysis of Aesthetic Results in Genioplasty
2.Invited Response on: Combination Therapy Involving Pulsed Dye and Fractional CO2 Laser Followed by Ultrasound-Assisted Transdermal Drug Delivery Technique for Hypertrophic Scars in Pediatric Patients
3.Bridging Short-Term Gains and Long-Term Realities: Reflections on “Psychological Well-being After Body Contouring Surgery
4.Response to: Comment on “The Effect of Platelet-Rich Fibrin on Block, Crushed and Diced Cartilage
5.The Revision of Vertical Prolabial Deficiency in Bilateral Cleft Lip Patients: Prolabium Lengthening by Nasolabial Muscle Reconstruction
6.Micropuncture Decompression With High-Dose Hyaluronidase for Early Reversal of Nasal Ischaemia from HA–Biostimulator Mixed Fillers: An Illustrative Case and Technical Algorithm
7.Dermo-Glandular Suspension Following Wise-Pattern Explantation-Mastopexy: Is it Reaching the Intended Heights?
8.A Muscle-Based Approach to Superior Orbital Sulcus Hollowness: Preseptal Orbicularis Oculi Flap in Upper Blepharoplasty
9.Application of Personalized 3D-Printed Silicone Implants in Rhinoplasty: An Animal Experimental Study
10.Combination of Autologous Costal Cartilage Harvest for Rhinoplasty and Breast Augmentation Through the Same Incision: Experience in a Vietnam Population and Outcomes
11.Elastic Compression Attenuates Inflammatory Response in a Model of Acute Subcutaneous Abdominal Inflammation
12.Menstrual Cycle Phase Does Not Affect Blood Loss in High-Energy Lipoabdominoplasty: A Prospective Controlled Study
13.The Blood Supply of the Lips: A Systematic Review and Meta-Analysis
14.iLips®: A 5-Years Experience with a Highly Reproducible Approach for Dynamic Lip Filler
15.Comment on “Enhancing Patient Comfort in Aesthetic BoNT-A Injections: Mechanical Versus Topical Analgesia”
16.Comments on “Preoperative GLP-1 Receptor Agonists and Thromboinflammatory Markers in Patients Undergoing Abdominoplasty: A Prospective Monocentric Study” by Bruno et al., 2026
17.The Octopus Mastopexy: A True “Implant-First” and On-Demand Approach Based on Parenchymal Reduction
18.Preexisting Depression or Anxiety is Associated with Increased Wound Complications Following Breast Reduction Surgery: A Real-World Cohort Study
19.Reconstructive Approach to Saddle Nose Deformity: A Diagnostic–Therapeutic Algorithm and the Preoperative Use of Hyaluronic Acid Filler for Skin Expansion in Rhinoplasty
20.Microneedling with Topical Insulin Versus Microneedling with Platelet-rich Plasma for Post-Acne Scars: A Systematic Review and Meta-Analysis with Trial Sequential Analysis
21.Age-stratified Discrepancy Between Expectations and Satisfaction in Facial Cosmetic Surgery: A Retrospective Cohort Analysis
22.Four Decades of the Anterolateral Thigh Flap: Celebrating a Milestone in Reconstructive Microsurgery
23.Defining the Vascular Anomalies in Maffucci Syndrome: A Systematic Review
24.PRISMA (Pectoralis–Rib Implant Support and Muscle Adjustment): An Innovative Technique for Secondary Mastopexy
25.Pectoralis Major Muscle Necrosis After Selective Arterial Embolization: A Case Report With Reconstructive Considerations
26.Safety Evaluation of the RibXcar Technique Using the Piezotome: An Analysis of Surgical Complications
27.Reply: Safety Evaluation of the RibXcar Technique Using the Piezotome: An Analysis of Surgical Complications
28.Muscle Tissue Remodeling Following Intramuscular Fat Grafting: Structural and Transcriptomic Insights
29.Safety of Biologic and Immune-modulating Agents in Breast Surgery Procedures: A Retrospective Cohort Analysis
30.Geographic and Socioeconomic Variation in Aesthetic Plastic Surgery Pricing Across the United States: A State-Level Analysis of Income, GDP, and Real Economic Burden
31.Nonsurgical Management of Submental Fullness for Double Chin Reduction: A Systematic Review
32.Application of a novel ingredient Blend promotes hair growth by modulating Wnt/β-catenin signaling, DP inductivity, and boosting elastin expression in healthy human scalp hair follicles ex vivo
33.Comparing the Efficacy and Safety of PRP and PRF on Periorbital Skin Quality: A Randomized Split-Face Clinical Trial
34.The worldwide burden of skin diseases: Lessons from the Global Burden of Disease data
35.On the likely physicochemical basis of the “ochre color” under ultraviolet-induced fluorescent dermoscopy
36.Mandibular Angle Osteotomy in Asian Patients： A Narrative Review on Techniques, Emerging Technologies, and Personalized Surgical Strategies
37.Impact of systemic tranexamic acid on postoperative drainage in large-volume reduction mammaplasty
38.Response to correspondence on: “THE KEYSTONE FLAP AS AN ESTHETIC MEANS FOR NASAL SOFT TISSUE RESTORATION
39.Correspondence on: Antidepressants and Postoperative Complications in Breast Reduction Surgery: A Propensity Score–Matched Multicenter Analysis
40.Integrated Analysis of Macrophage-Associated Necroptosis in Alopecia Areata
41.Hybrid C-V and Star Flap Technique for Nipple Reconstruction: A Case Report
42.Autoimmune/Inflammatory Syndrome Induced by Hyaluronic Acid and Hyaluronidase
43.BB8 Technique: An Innovative Approach for Delivering Diluted Belotero® Balance to Treat Infraorbital Hollows
44.Cosmetic Principles and Contemporary Techniques: Achieving Aesthetic Outcomes in DIEP Flap Breast Reconstruction
45.A decade of hair-loss clinical trials: a registry-based analysis of studies registered on ClinicalTrials.gov
46.Tanorexia: The Psychodermatology of Compulsive Tanning
47.High-Level Secretory Expression of Recombinant Type XVII Human-like Collagen in Komagataella phaffii
48.Therapeutic Effects of Glucagon-like Peptide-1 Receptor Agonists in Non-Alcoholic Fatty Liver Disease: A Systematic Review
49.Generative artificial intelligence in plastic surgery: emerging applications in preoperative psychological screening and patient empowerment
50.Study on three-dimensional reconstruction-enhanced case-based learning for teaching nasal base depression to trainees
51.Safety and Effectiveness of Two Reconstitution Volumes of Poly-L-Lactic Acid for Correction of Décolletage Wrinkles
52.Efficacy and Safety of Clascoterone Cream 1% and Adapalene Gel 0.3% in Patients With Acne
53.Psychotherapeutic Interventions in Acne Vulgaris: A Call for Future Research
54.FULL SUPPLEMENT: Emerging Topical Approaches in the Management of Female Pattern Hair Loss
55.INDIVIDUAL ARTICLE: Efficacy of a Dual-Serum Cosmetic System in Women With Female Pattern Hair Loss
56.Iron Oxides in Tinted Sunscreen for Hyperpigmentation: A Product Analysis and Literature Review
57.Dynamic regulation of the tissue microenvironment by integrins and the extracellular matrix
1. 评《基于人工智能的颏成形术美容效果定量客观分析》
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2026-06-23
Canada is the first country to approve a new botulinum neurotoxin serotype for aesthetic use
Boey® is the first and only rapid-onset and short-duration botulinum neurotoxin serotype E approved for the temporary improvement in the appearance of glabellar lines
Boey® offers a differentiated treatment option for many people who are curious about facial injectables
Results may be seen as early as eight hours after treatment and typically wear off within approximately two to three weeks
BOTOX Cosmetic® (onabotulinumtoxinA) is the only neurotoxin clinically tested for use following treatment with Boey®
IRVINE, Calif., June 23, 2026 /PRNewswire/ -- Today, Allergan Aesthetics, an AbbVie company (NYSE: ABBV), announced Health Canada has approved Boey® (trenibotulinumtoxinE) for the temporary improvement in the appearance of moderate to severe lines between the eyebrows (glabellar lines) in adult patients.
Boey® is the first and only rapid-onset and short-duration botulinum neurotoxin serotype E approved for the temporary improvement in the appearance of glabellar lines.
"Health Canada's approval of Boey® marks an important scientific and regulatory milestone in advancing toxin science. As the world's first approval of a botulinum neurotoxin based on serotype E in aesthetics, Boey® represents a meaningful advancement in aesthetic medicine — a fast-acting neurotoxin with a differentiated profile that expands the treatment options for clinicians and patients," said Roopal Thakkar, M.D., executive vice president, research and development, chief scientific officer, AbbVie.
A new Allergan Aesthetics survey found that 80% of people are open to learning about new treatments to get the results they want and 79% wish they could temporarily preview the outcome of an aesthetic treatment. 1 Despite growing interest in facial injectables, many patients are hesitant to take the next step due to uncertainty around treatment outcomes and committing to long-lasting results. Boey® was developed for these patients, offering a new way to experience neurotoxin treatment.
"Boey® represents an important new advancement for patients and healthcare professionals, addressing a key need in aesthetic neurotoxins. With its truly differentiated profile, Boey® is redefining aesthetics and expanding what's possible by giving practitioners another option to tailor treatment to individual needs and goals, specifically, the ability to try a toxin without the long-term commitment," said Nicole Mowad-Nassar, senior vice president, AbbVie and president, global Allergan Aesthetics. "Allergan Aesthetics is proud to bring this innovation to Canada first and to continue advancing options that help shape the future of aesthetic medicine."
Developed by the makers of BOTOX Cosmetic®, Boey® offers a new option for suitable patients considering facial injectables. BOTOX Cosmetic® is the only neurotoxin clinically tested for use following treatment with Boey®.
Allergan Aesthetics plans to begin training healthcare professionals on the appropriate use of Boey® and is preparing for a commercial launch in the upcoming months as trenibotulinumtoxinE is under review for approval in multiple other countries.
Allergan Aesthetics develops, manufactures and markets a portfolio of leading aesthetics brands and products. Allergan Aesthetics is well positioned to lead the future of injectable aesthetics, with dedicated research and development focused on driving innovation to meet the evolving needs of patients and healthcare professionals worldwide.
-ENDS-
About the Boey® clinical studies
The approval of Boey® is supported by data from two randomised, multi-centre, double-blind, placebo-controlled studies Phase 3 clinical trials evaluating the efficacy and safety of Boey® in adults with moderate to severe glabellar lines (M21-500 and M21-508) associated with corrugator and/or procerus muscle activity. The studies enrolled 947 patients treated with Boey® 700 U total dose or placebo.
The primary efficacy measure was defined as the percentage of subjects achieving None or Mild and ≥ 2-Grade Improvement from baseline in glabellar line severity at maximum frown based on both investigator and subject assessments using the Facial Wrinkle Scale (FWS) at Day 7. Efficacy was assessed in the ITT population. The composite responder rates at Day 7 were 60.0% and 65.7% (M2-500: n=289/482; M21-508: n=149/227; p<0.0001).
Secondary efficacy endpoints were measured by Facial Line Satisfaction Questionnaire (FLSQ), a validated scale developed by Allergan Aesthetics, and included satisfaction with achieving a natural look and overall satisfaction with treatment effect.
The onset of effect for patients treated with Boey® appeared as early as 8 hours after injection in both pivotal studies. Glabellar lines returned to baseline severity in approximately 14-21 days after administration.
The most frequently reported treatment-related adverse events were headache (3.4% in the Boey-treated group and 4.2% in the placebo-treated group), injection site pain (1.7% in the Boey-treated group and 2.9% in the placebo-treated group), and injection site erythema (0.6% in the Boey-treated group and 1.3% in the placebo-treated group).2
BOEY
®
CANADA APPROVED USES AND IMPORTANT SAFETY INFORMATION
Boey® is used in adults to temporarily improve the appearance of moderate to severe frown lines between the eyebrows (glabellar/frown lines).
IMPORTANT SAFETY INFORMATION
Boey
®
may cause serious side effects, including:
Distant spread of toxin effects. It is possible that the effect of botulinum toxin may affect areas of the body away from the injection site and cause symptoms of a serious condition called botulism. Trouble breathing and trouble swallowing can be life threatening.
One unit (amount) of Boey® is NOT the same as one unit of other botulinum products.
Boey® should only be given by a trained healthcare professional. They should have experience using Boey®.
Follow the dose and schedule of injection recommended by your healthcare provider.
Do not use Boey® if you are allergic to botulinum toxin or any of the other ingredients or you have a skin infection where you plan to get the injection
To help avoid side effects and ensure proper use, talk to your healthcare professional before you take Boey®. Talk about any health conditions or problems you may have, including if you have allergies to any botulinum toxin product, had a side effect from any botulinum toxin product in the past, have had facial surgery or injured your face, are planning to have facial surgery soon, have any redness or swelling (inflammation) where you plan to get an injection, muscles where the injection will be given are weak, have drooping of one or both eyelids (ptosis), have any other change in the way your face normally looks, have certain diseases that affect your nervous system (such as amyotrophic lateral sclerosis or motor neuropathy)
Other warnings you should know about include:
Injection site reactions: Like with any injection procedure, injection site reactions may happen after receiving Boey®. Symptoms at the injection site(s) may include pain/discomfort, swelling/inflammation, redness, bruising, bleeding, itching, warmth, hardness at the site where the needle entered your skin
Muscle weakness in areas next to or near the injection sites such as eyelid drooping and double vision (seeing two objects when there is only one).
Driving and using machines: If you have drooping eyelids or problems with your vision after using Boey®, do not drive or use machinery until those symptoms go away.
After you get Boey®, talk to your healthcare professional if you have the following:
Allergic reaction: An allergic reaction is a reaction your body has to a medicine. This can cause symptoms such as hives, rash, or fever. Contact your healthcare professional right away if you have any of the symptoms listed as they can be signs of a severe allergic reaction: trouble breathing, swallowing, or speaking, swelling, including swelling of the face or throat, wheezing (a whistling sound while breathing), feeling dizzy or light-headed, shortness of breath
Distant
spread of toxin effect: Sometimes, the effects of botulinum toxin may spread from the injection area to other parts of the body. Contact your healthcare provider right away if you have any of the symptoms listed: muscle weakness, trouble swallowing, unwanted food or liquid going into the airways
Reduced blinking or experience dryness in one or both eyes.
Tell your healthcare professional about all the medicines you take, including any drugs, vitamins, minerals, natural supplements or alternative medicines. The following may interact with Boey®: a different medicine that has botulinum toxin, muscle relaxants (medicines that reduce muscle tension), antibiotics (medicines used to treat infections)
, anticholinergics (medicines that reduce muscle strength). Ask your healthcare provider for advice before you take any new medicines.
Boey® can have side effects, although not everybody gets them, including drooping eyelid (uncommon), drooping eyebrow (uncommon), or raising of the outer eyebrow (rare).
These are not all the possible side effects you may have when taking Boey®. If you experience any side effects not listed here, tell your healthcare professional.
Please consult the Boey® product monograph for more information.
BOTOX® COSMETIC US APPROVED USES AND IMPORTANT SAFETY INFORMATION
BOTOX® Cosmetic is a prescription medicine that is injected into muscles and used to temporarily improve the look of moderate to severe forehead lines, crow's feet lines, frown lines between the eyebrows, and vertical bands connecting the jaw and neck (platysma bands) in adults.
IMPORTANT SAFETY INFORMATION
BOTOX® Cosmetic may cause serious side effects that can be life threatening. Get medical help right away if you have any of these problems any time (hours to weeks) after injection of BOTOX® Cosmetic:
Problems swallowing, speaking, or breathing, due to weakening of associated muscles, which can be severe and result in loss of life. You are at the highest risk if these problems are preexisting before injection. Swallowing problems may last for several months.
Spread of toxin effects. The effect of botulinum toxin may affect areas away from the injection site and cause serious symptoms, including loss of strength and all-over muscle weakness, double vision, blurred vision and drooping eyelids, hoarseness or change or loss of voice, trouble saying words clearly, loss of bladder control, trouble breathing, and trouble swallowing.
BOTOX® Cosmetic dosing units are not the same as, or comparable to, any other botulinum toxin product.
There has not been a confirmed serious case of spread of toxin effect when BOTOX® Cosmetic has been used at the recommended dose to treat frown lines, crow's feet lines, forehead lines, and/or platysma bands.
BOTOX® Cosmetic may cause loss of strength or general muscle weakness, vision problems, or dizziness within hours to weeks of receiving BOTOX® Cosmetic.
If this happens, do not drive a car, operate machinery, or do other dangerous activities.
Serious and/or immediate allergic reactions have been reported, including itching, rash, red itchy welts, wheezing, asthma symptoms, or dizziness or feeling faint. Get medical help right away if you are wheezing or have asthma symptoms, or if you become dizzy or faint.
Do not receive BOTOX® Cosmetic if you are allergic to any of the ingredients in BOTOX® Cosmetic (see Medication Guide for ingredients); had an allergic reaction to any other botulinum toxin product such as Myobloc (rimabotulinumtoxinB), Dysport (abobotulinumtoxinA), Xeomin (incobotulinumtoxinA), Jeuveau (prabotulinumtoxinA-xvfs), Daxxify (daxibotulinumtoxinA-lanm), or Letybo (letibotulinumtoxinA-wlbg); or have a skin infection at the planned injection site. This list may not include all available botulinum toxin products.
Tell your doctor about all your muscle or nerve conditions, such as ALS or Lou Gehrig's disease, myasthenia gravis, or Lambert-Eaton syndrome, as you may be at increased risk of serious side effects, including difficulty swallowing and difficulty breathing, from standard doses of BOTOX® Cosmetic.
Tell your doctor about all your medical conditions
, including surgery or plans to have surgery on your face, trouble raising your eyebrows, drooping eyelids, any other abnormal facial change, are pregnant or plan to become pregnant (it is not known if BOTOX® Cosmetic can harm your unborn baby), or are breastfeeding or plan to (it is not known if BOTOX® Cosmetic passes into breast milk).
Tell your doctor about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements. Using BOTOX® Cosmetic with certain other medicines may cause serious side effects.
Do not start any new medicines until you have told your doctor that you have received BOTOX® Cosmetic in the past.
Tell your doctor if you have received any other botulinum toxin product in the last 4 months; have received injections of botulinum toxin such as Myobloc, Dysport, Xeomin, Jeuveau, Daxxify, or Letybo in the past (tell your doctor exactly which product you received); have recently received an antibiotic by injection; take muscle relaxants; take an allergy or cold medicine; take a sleep medicine; or take aspirin-like products or blood thinners.
Other side effects of BOTOX® Cosmetic include dry mouth; discomfort or pain at the injection site; tiredness; headache; neck pain; and eye problems, including double vision, blurred vision, decreased eyesight, drooping eyelids and eyebrows, swelling of eyelids, and dry eyes.
For more information, refer to the Medication Guide or talk with your doctor.
To report a side effect, please call Allergan Aesthetics at 1-800-678-1605.
Please see BOTOX®
Cosmetic full US
Product Information
,
including Boxed Warning and
Medication Guide
.
© 2026 AbbVie. All rights reserved. All trademarks are the property of their respective owners.
About Boey®
Boey® is a facial injectable neurotoxin serotype E indicated in adult patients for the temporary improvement in the appearance of of moderate to severe glabellar lines associated with corrugator and/or procerus muscle activity. It blocks neuromuscular transmission as the neurotoxin cleaves SNAP-25. It has a rapid uptake and translocation into neuronal cells, with a short half-life of the type E light chain, giving it a rapid onset of action and a short duration of effect when treating glabellar lines.2
About Glabellar lines
Glabellar lines are the vertical lines that appear between the eyebrows and are commonly referred to as "frown lines". These lines develop over time due to repeated muscle contractions from facial expressions such as frowning, concentrating or squinting.
About Allergan Aesthetics
At Allergan Aesthetics, an AbbVie company, we develop, manufacture, and market a portfolio of leading aesthetics brands and products. Our aesthetics portfolio includes facial injectables, body contouring, plastics, skin care, and more. Our goal is to consistently provide our customers with innovation, education, exceptional service, and a commitment to excellence, all with a personal touch. For more information, visit
About AbbVie
AbbVie's mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people's lives across several key therapeutic areas including immunology, neuroscience and oncology – and products and services in our Allergan Aesthetics portfolio. For more information about AbbVie, please visit us at . Follow @abbvie on LinkedIn, Facebook, Instagram, X and YouTube.
Forward-Looking Statements
Some statements in this news release are, or may be considered, forward-looking statements for purposes of the Private Securities Litigation Reform Act of 1995. The words "believe," "expect," "anticipate," "project" and similar expressions and uses of future or conditional verbs, generally identify forward-looking statements. AbbVie cautions that these forward-looking statements are subject to risks and uncertainties that may cause actual results to differ materially from those expressed or implied in the forward-looking statements. Such risks and uncertainties include, but are not limited to, challenges to intellectual property, competition from other products, difficulties inherent in the research and development process, adverse litigation or government action, changes to laws and regulations applicable to our industry, the impact of global macroeconomic factors, such as economic downturns or uncertainty, international conflict, trade disputes and tariffs, and other uncertainties and risks associated with global business operations. Additional information about the economic, competitive, governmental, technological and other factors that may affect AbbVie's operations is set forth in Item 1A, "Risk Factors," of AbbVie's 2025 Annual Report on Form 10-K, which has been filed with the Securities and Exchange Commission, as updated by its Quarterly Reports on Form 10-Q and in other documents that AbbVie subsequently files with the Securities and Exchange Commission that update, supplement or supersede such information. AbbVie undertakes no obligation, and specifically declines, to release publicly any revisions to forward-looking statements as a result of subsequent events or developments, except as required by law.
FOOTNOTES
* A global survey (28th November 2025 – 15th December 2025) of N=12,286 adults aged 18+ who have paid for at least 2 beauty or aesthetics related services in the past year (Brazil n=1318, Canada n=1304, China n=1318, France n=1302, Germany n=1301, KSA n=1311, Thailand n=1321, USA n=1802, UK n=1309).1
References
Allergan Aesthetics Holistic Beauty Global Research. REF-148616. January 2026
Boey® Product Monograph. AbbVie 2026.
-ENDS-
Contacts:
Allergan Aesthetics Media:
Michael Salzillo
+1 (908) 269-1688
[email protected]
AbbVie Investors:
Liz Shea
+1 (847) 935-2211
[email protected]
© 2026 AbbVie. All rights reserved. All trademarks are the property of their respective owners.
SOURCE AbbVie
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临床结果上市批准临床3期
100 项与 OnabotulinumtoxinA (VA Office of Research and Development) 相关的药物交易
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| 适应症 | 最高研发状态 | 国家/地区 | 公司 | 日期 |
|---|---|---|---|---|
| 下尿路症状 | 临床2期 | 美国 | 2012-06-01 | |
| 前列腺增生症 | 临床2期 | 美国 | 2012-06-01 |
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临床结果
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| 研究 | 分期 | 人群特征 | 评价人数 | 分组 | 结果 | 评价 | 发布日期 |
|---|
临床3期 | - | (Female and female-assigned patients) | 積壓範醖醖鏇獵願廠膚(壓壓憲壓製簾鹽衊廠窪) = 範醖廠選齋窪願餘範憲 衊鑰膚築夢製積醖選繭 (觸遞願糧壓廠簾衊餘範 ) 更多 | 积极 | 2024-04-09 | ||
(Male and male-assigned patients) | 積壓範醖醖鏇獵願廠膚(壓壓憲壓製簾鹽衊廠窪) = 遞鬱遞淵網憲遞積齋壓 衊鑰膚築夢製積醖選繭 (觸遞願糧壓廠簾衊餘範 ) 更多 | ||||||
临床3期 | 408 | 繭膚鑰選艱簾願鹹築範(簾齋製壓積遞製繭網鬱) = 淵淵餘艱願選繭淵蓋壓 鬱齋鹽範衊鏇製獵鹹醖 (製餘獵襯憲壓顧憲構膚 ) 更多 | 积极 | 2024-03-08 | |||
Placebo | 繭膚鑰選艱簾願鹹築範(簾齋製壓積遞製繭網鬱) = 構窪糧簾獵觸餘糧築製 鬱齋鹽範衊鏇製獵鹹醖 (製餘獵襯憲壓顧憲構膚 ) 更多 | ||||||
临床3期 | 426 | 遞憲夢鹽憲簾夢製蓋廠(窪獵鑰觸積願積選觸艱) = 艱繭構簾範範觸積構鹹 衊繭襯艱簾醖艱鹹膚繭 (鹹夢襯觸鬱憲觸願簾築 ) 更多 | 积极 | 2024-03-08 | |||
Placebo | 遞憲夢鹽憲簾夢製蓋廠(窪獵鑰觸積願積選觸艱) = 鬱鬱鹽窪鏇蓋夢鹹膚蓋 衊繭襯艱簾醖艱鹹膚繭 (鹹夢襯觸鬱憲觸願簾築 ) 更多 | ||||||
N/A | 三线 | 209 | 鑰選鬱窪鏇網壓齋構淵(選構積憲鏇願鏇膚製構) = 齋膚網選餘壓製醖構積 衊襯夢構選觸壓築窪憲 (構鹹鬱簾壓遞膚築淵鹹 ) | - | 2023-04-01 | ||
N/A | 膀胱过度活动症 二线 | 三线 | 272 | 餘淵夢積憲憲顧繭築蓋(鏇糧積範淵膚遞衊齋齋) = 簾鬱遞餘鑰淵簾窪淵壓 獵願鏇餘獵遞製網構壓 (夢製襯鬱獵獵鏇蓋壓糧 ) 更多 | - | 2023-04-01 | ||
餘淵夢積憲憲顧繭築蓋(鏇糧積範淵膚遞衊齋齋) = 繭範選構遞醖鬱網鹽願 獵願鏇餘獵遞製網構壓 (夢製襯鬱獵獵鏇蓋壓糧 ) 更多 | |||||||
N/A | 59 | 選簾膚積積壓構鏇窪鏇(構壓齋範範網築壓蓋蓋) = Dysphagia was reported in 4 patients 艱夢夢觸廠衊繭壓繭鏇 (鏇蓋鹽廠襯襯餘鹽積鹹 ) | 积极 | 2022-09-15 | |||
临床2期 | 63 | Tamsulosin + placebo+onaBoNT-A + placebo (ARM 1: onaBoNT-A + Placebo) | 網觸選壓顧築鹹窪襯網(鹽齋鏇壓顧夢鑰獵構網) = 餘衊夢鹽網鏇淵選襯鬱 鬱遞獵淵鏇獵夢糧鏇築 (壓鏇製夢夢遞淵艱積觸, 0.07) 更多 | - | 2021-10-05 | ||
Tamsulosin + placebo+onaBoNT-A + placebo (ARM 2: Saline + Tamsulosin) | 網觸選壓顧築鹹窪襯網(鹽齋鏇壓顧夢鑰獵構網) = 鬱窪網壓窪獵鹽蓋簾簾 鬱遞獵淵鏇獵夢糧鏇築 (壓鏇製夢夢遞淵艱積觸, 0.05) 更多 | ||||||
N/A | - | 簾憲範願願艱淵廠窪網(顧製遞衊遞淵遞鹽膚廠) = The most common AEs (dysphagia, muscular weakness) were similar 顧網築願膚鏇範構觸鹽 (製願鹽繭選膚獵鏇觸艱 ) | - | 2021-09-17 | |||
N/A | - | - | 膚選憲製構衊繭壓積膚(壓鹽簾鑰繭簾餘觸築願) = 願選糧襯網夢構廠鏇窪 蓋築鏇膚範鹹襯鑰鏇廠 (願廠壓範鹹鬱壓遞淵餘 ) | 积极 | 2018-04-01 | ||
Placebo | 膚選憲製構衊繭壓積膚(壓鹽簾鑰繭簾餘觸築願) = 願蓋夢鏇構憲醖膚鑰憲 蓋築鏇膚範鹹襯鑰鏇廠 (願廠壓範鹹鬱壓遞淵餘 ) | ||||||
N/A | 三线 | - | (Elderly cohort) | 襯構鏇憲齋範襯鹹顧鑰(製衊淵顧蓋遞願膚鏇獵) = 蓋淵遞鏇憲築夢簾膚衊 壓襯繭顧構積膚願鹹築 (蓋壓襯衊壓衊鏇選壓襯 ) 更多 | - | 2018-04-01 | |
(Younger cohort) | 襯構鏇憲齋範襯鹹顧鑰(製衊淵顧蓋遞願膚鏇獵) = 鑰鹽糧廠構艱範膚構顧 壓襯繭顧構積膚願鹹築 (蓋壓襯衊壓衊鏇選壓襯 ) 更多 |
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