Phase 1/2 RAINFOL™-01 data showed the combination of rinatabart sesutecan (Rina-S®) and bevacizumab was tolerable, with no new safety signals in patients with advanced ovarian cancer The ongoing Phase 3 RAINFOL-04 trial will further evaluate the combination in patients with recurrent platinum-sensitive ovarian cancer (PSOC) Genmab A/S (Nasdaq: GMAB) announced today new data demonstrating that rinatabart sesutecan (Rina-S®), an investigational folate receptor alpha (FRα)-targeted, topoisomerase

April 13, 2026 -- Kazia Therapeutics Limited (Nasdaq: KZIA), a clinical-stage oncology company advancing therapies to reprogram cancer biology and overcome treatment resistance, announces the in-licensing of a first-in-class SETDB1-targeted epigenetic drug development platform from QIMR Berghofer. The platform includes use of an AI-integrated epigenetic drug discovery engine, enabling rapid, precise, and scalable candidate generation. The lead drug candidate, MSETC, was discovered and optimized

Novel TBL1 targeting strategy drives nuclear β-catenin degradation, inhibits oncogenic transcription, and demonstrates potent anti-tumor activity in complex solid tumors The company continues to build clinical momentum in hepatocellular carcinoma while expanding development into colorectal cancer, as well as other Wnt-driven cancers April 13, 2026 -- Iterion Therapeutics announced that two abstracts featuring its first-in-class TBL1 inhibitor, tegavivint, will be presented at the 2026 American

BioOra and Cincinnati Children's unite to evaluate Atla-cel in paediatric relapsed or refractory B-ALL, building on emerging adult clinical data demonstrating markedly reduced neurotoxicity with this next-generation CAR-T therapy. BioOra and Cincinnati Children's are partnering to advance Atla-cel, a paediatric CAR‑T therapy for relapsed/refractory B‑ALL. Atla‑cel shows markedly reduced neurotoxicity in adult trials, supporting its evaluation in children who could benefit from this therapy not

Financing will support the ongoing Phase 1/2 trial of NEO-811 for the treatment of locally advanced or metastatic non-resectable clear cell renal cell carcinoma (ccRCC) and the continued advancement of the company’s broader novel molecular glue degrader pipeline April 13, 2026 -- Neomorph, Inc., a biotechnology company pioneering molecular glue degraders to address previously undruggable proteins, today announced the closing of a $100 million Series B financing. The round was led by Deerfield

Mackay Base Hospital activated March 31, 2026 as first clinical trial site; first patient dosed within days of activation — a signal of strong enrollment velocity and significant unmet medical need April 13, 2026 -- Oragenics, Inc. (NYSE American: OGEN), a clinical-stage biotechnology company developing brain-targeted therapeutics through proprietary intranasal delivery technology, today announced that the first patient has been dosed in its ongoing Phase IIa clinical trial evaluating ONP-002,

The FDA on Monday approved Travere Therapeutics' dual endothelin angiotensin receptor antagonist Filspari (sparsentan) to reduce proteinuria in focal segmental glomerulosclerosis (FSGS), giving patients their first authorised therapy for the rare kidney disorder. The green light also extends the drug's reach beyond its earlier use in IgA nephropathy. The new indication applies to adults and children aged eight years and older with FSGS who do not have nephrotic syndrome. "This approval…builds

April 13, 2026 -- Sichuan Kelun-Biotech Biopharmaceutical Co., Ltd. ("Kelun-Biotech" or the "Company", 6990.HK) announced that results from both the ovarian cancer cohort and the cervical cancer cohort of Phase II study SKB264-II-06/MK-2870-002 of the TROP2 ADC sacituzumab tirumotecan (sac-TMT, also known as SKB264/MK-2870) (佳泰莱®), in combination with MSD's[1] anti-PD-1 monoclonal antibody pembrolizumab (KEYTRUDA®[2]), were selected for oral presentation at the 2026 Society of Gynecologic Oncolo

April 13, 2026- Health Canada has granted a Notice of Compliance (NOC) for Saphnelo® (anifrolumab injection) for subcutaneous self-administration via a single-use autoinjector for adult patients with active, autoantibody positive systemic lupus erythematosus (SLE) in addition to standard therapy. The approval by Health Canada was based on positive results from the interim analysis of the Phase III TULIP-SC trial. In the trial, the subcutaneous administration of anifrolumab led to a statistically

BRUIN CLL-322 is the first Phase 3 readout in CLL to utilize and outperform a venetoclax-containing control arm This trial predominantly enrolled a patient population previously treated with covalent BTK inhibitors, highly relevant to current practice These results mark the fourth positive Phase 3 study of pirtobrutinib in CLL April 13, 2026 -- Eli Lilly and Company (NYSE: LLY) today announced positive topline results from the Phase 3 BRUIN CLL-322 trial of Jaypirca (pirtobrutinib), a non-coval