Data demonstrated in vitro and in vivo ITK inhibition with soquelitinib induced switching of proinflammatory Th17 cells into anti-inflammatory Treg cells Publication confirms and extends understanding of ITK inhibition mechanism of action and its potential in inflammatory autoimmune and allergic diseases Data published by leading researchers from Cornell University in peer-reviewed journal Science Signaling July 25, 2024 -- Corvus Pharmaceuticals, Inc. (Corvus or the Company) (Nasdaq: CRVS), a

ALL represents 10% of all leukemia cases in the United States, progresses rapidly, and is typically fatal within weeks or months if left untreated1 There is an urgent need to develop new therapies for ALL for patients who are not candidates for hematopoietic stem cell transplantation (HSCT) or relapse after FDA ODD and RPDD designations for UCART22 marks an important step towards developing allogeneic CAR T products that would be readily available for all patients July 25, 2024 -- Cellectis (th

前列腺癌是美国男性第二大常见癌症，更是 50 岁以上男性最常见的癌症。事实上，在男性一生中，每七位就有一人会被诊断出患有前列腺癌。而在中国，前列腺不论在每年新病例和死亡人数也都是偏高的癌症之一，仅次于肺癌、大肠癌、肝癌、胃癌和食道癌五大杀手。 尽管发病率居高不下，前列腺癌治愈前景依然充满希望。“前列腺癌若能在早期被发现，并由经过严格训练的专业人士，利用最前沿的治疗手段和技术进行干预，其治疗前景是非常乐观的。”希望之城橘县分院泌尿外科医学主任 Jeffrey S. Yoshida 医学博士表示。 Yoshida 博士因其专业技术和出色的病人护理而享誉全美。他利用最先进的达芬奇机器人系统，为需要手术治疗的前列腺癌患者成功实施了近 4,000 例机器人手术。 “对于许多患者来说，微创手术已成为一种常见的治疗选择。机器人手术通常能减少副作用，帮助患者更快康复。希望之城在这一领域率先垂范，为前列腺癌及其他泌尿系统癌症患者成功实施了数千例机器人手术，这一数字远超美国西部的任何其他医院。” Yoshida 博士说道。 希望之城橘县分院提供了前列腺癌检测的黄金标准——即精准靶向的经会阴前列腺活

2024年7月26日，专注于可视化诊疗一体靶向放射性核素疗法（TRT）的生物技术公司晶核生物宣布完成A轮融资。本轮融资由华金投资和华金大道联合领投，泰格医药跟投，老股东高榕创投和骊宸资本持续投资。 融资资金将主要用于JH02的全球临床I/II期试验、68Ga-JH03/177Lu-JH04的中美IND申报及临床开发，以及后续多个创新性管线临床前研究和国际合作。 晶核生物成立于2021年，由4位丰富经验的靶向核药科学家联合创建，拥有多款创新核药开发并成功上市的经验。公司致力于开发下一代靶向放射性核素疗法（TRT），以此改善患者生活。 靶向放射性药物通过偶联因子将具有靶向的分子与放射性核素进行偶联，利用精准靶向分子递送到全身性病灶，通过放射性核素的变化药物可以实现可视化诊断与治疗一体化。 截至目前，晶核生物已经构建了靶向核药开发的专有技术平台，用于配体筛选、调制偶联因子（J-Linker）和临床转化。通过J-Linker多功能偶联平台，可以有效提高药物在疾病部位的暴露量，并降低其它器官的暴露量，进而为晶核生物在研管线带来更好的治疗效果和更宽的安全窗口。 2023年7月，晶核生物自主

July 24, 2024 -- Catalyst Pharmaceuticals, Inc. ("Catalyst" or "Company") (Nasdaq: CPRX), a commercial-stage biopharmaceutical company focused on in-licensing, developing, and commercializing novel medicines for patients living with rare and difficult-to-treat diseases, today announced that it has entered into a License, Supply, and Commercialization Agreement with Kye Pharmaceuticals Inc., ("Kye" or "Kye Pharmaceuticals") granting Kye the exclusive Canadian commercial rights to AGAMREE® (vamor

July 24, 2024 -- ConSynance Therapeutics, Inc., a clinical-stage biopharmaceutical company developing first-in-class therapies for rare central nervous system (CNS) disorders, today announced that the U.S. Food and Drug Administration (FDA) has granted Rare Pediatric Disease Designation (RPDD) to its investigational drug CSTI-500 for the treatment of Prader-Willi Syndrome (PWS) in children and adolescents. “Receiving RPDD from the FDA is a significant regulatory milestone for ConSynance as we

Ad hoc announcement pursuant to art. 53 SIX Swiss Exchange Listing Rules Sandoz launches biosimilar Pyzchiva® (ustekinumab) across Europe, to treat chronic inflammatory diseases Launch across Europe, starting today, strengthens well-established Sandoz immunology portfolio in Europe, leveraging existing footprint Pyzchiva® first ustekinumab biosimilar to launch in Europe with all reference medicine strengths, including 130mg vial initiation dose for Crohn’s disease Pyzchiva® to treat adults with

July 23, 2024 -- Mesoblast Limited (Nasdaq:MESO; ASX:MSB), global leader in allogeneic cellular medicines for inflammatory diseases, announced that the United States Food and Drug Administration (FDA) has accepted its Biologics License Application (BLA) resubmission for Ryoncil® (remestemcel-L) in the treatment of children with steroid-refractory acute graft versus host disease (SR-aGVHD). FDA considers the resubmission to be a complete response and Mesoblast anticipates a decision on or before

Grünenthal以全股票交易方式收购Valinor Pharma，并成为Movantik® (naloxegol)全球权利的所有者 Valinor Pharma自2023年初开始拥有Movantik，并利用Apollo Care的商业平台扩大了Movantik在美国的销量，同时降低了毛净成本和运营成本 第一季度财务亮点包括收入增长150%和有史以来最高的EBITDA 2024年7月23日-- Valinor Pharma, LLC（以下简称“Valinor”）今天宣布被Grünenthal收购，总交易价值约为2.5亿美元的预付现金对价。 Valinor首席执行官Todd N. Smith表示：“今天的公告认可了我们为患者和股东创造的重大价值。 此次收购恰逢其时，因为Valinor实施了一个创新的销售和患者访问工具商业平台，这将为Grünenthal的未来增长奠定坚实的基础。” 在过去的12个月中，Valinor与Apollo Care合作，实施了一整套集成销售、分析、患者访问和毛利到净值管理解决方案，为创纪录的处方增长奠定了基础，同时降低了毛净成本和运营成本。 Valinor总裁B

July 24, 2024 -- Annovis Bio Inc. (NYSE: ANVS) (“Annovis” or the “Company”), a late-stage clinical drug platform company pioneering transformative therapies for neurodegenerative disorders such as Alzheimer’s disease (AD) and Parkinson’s disease (PD), announced today the issuance of a U.S. patent for methods of treating acute traumatic brain injuries (TBI) with its lead drug candidate, buntanetap. In 2016, the Company filed a patent covering the treatment of various nerve insults, including TB