AiCuris 'sharpens strategic focus' to immune-compromised at expense of other programs

2023-07-06
临床3期
Heading up AiCuris’ refocused pipeline will be Pritelivir, which is in phase 3 development to treat acyclovir-resistant herpes simplex virus infections.
AiCuris is AiCurisg down on its infectious disePritelivirne at the expense of its COVID-19 and foot acycloviracyclovir-resistant herpes simplex virus infections
AiCurisning its strategic focus” on a portfolio of therapies for infectious diseasCOVID-19munocfoot infectionients means the biotech will be able to accelerate development plans and prepare for market launch, the Wuppertal, Germany-based company said in a July 6 release.
The knock-on effect is that AiCuris “will discontinue research acinfectious diseases this strategic scope.” While the company didn’t go into details of what activities will be scrapped, the COVID-19 therapy AIC649 was notable for its absence from today’s release.
The company received 5.9 milAiCurisR ($6.4 million) in funding from a regional German government last year to advance the immune modulator as a potential way to slow progression of COVID-19.COVID-19rapy had AIC649ndergoing a clinical study in Germany and Africa.
Another program that wasn’t name-checked today was AiCuris’ collaboration with fellow German biotech Lysando. The two companies were working on Artilysin, a potential treatment for COVID-19, chronic wounds such as diabetic foot infections.
“Unfortunately, anti-infective treatment options for this growing patient population are often limiteLysandoew companies are focusing on developArtilysinpriate therapeutic candidateinfected, chronic woundswards saidiabetic foot infectionsstrategic change will allow us to be more efficient and effective from an operations perspective and ensure we are able to bring novel treatment options to patients in need.”
Heading up AiCuris’ refocused pipeline will be Pritelivir, which is in phase 3 development to treat acyclovir-resistant herpes simplex virus infections in immunocompromised patients. ToAiCurisata is due at the end of 2024.
Then there’AiCuris8, an anti-sense RNA therapy Pritelivirer the clinic early next year to prevent BKacycloviracyclovir-resistant herpes simplex virus infectionshe biotech is also working on preclinical programs designed to combat human adenovirus infections, with a key goal being to develop the first topical treatment specifically designed for ADV infections of the eye.
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