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概览

排名前五的药物类型	数量

小分子化药	1

排名前五的靶点	数量

ADRA1(肾上腺素能受体α-1家族)	1

关联

1

项与贵州一康药业有限公司相关的药物

Naftopidil

萘哌地尔

靶点

ADRA1

作用机制

ADRA1拮抗剂

在研机构

贵州一康药业有限公司 [+1]

原研机构

F. Hoffmann-La Roche Ltd.

在研适应症

排尿困难 [+1]

非在研适应症

医疗器械不适 [+4]

最高研发阶段批准上市

首次获批国家/地区

日本

首次获批日期1998-12-25

100 项与贵州一康药业有限公司相关的临床结果

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0 项与贵州一康药业有限公司相关的专利（医药）

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3

项与贵州一康药业有限公司相关的文献（医药）

2004-11-01·Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica

[Determination of orientin and vitexin in Trollius chinesis preparation by HPLC].

Article

作者: Wang, Li ; Liu, Zhi ; Xu, Zu-chao ; Li, Wen ; Huang, Yong

OBJECTIVETo establish a HPLC method for determining orientin and vitexin in Trollius chinesis preparation.METHODThe separation was carried out on Hypersil ODS column with a mixture of acetonitrile-1% acetic acid solution (15:85) as the mobile phase, at a flow rate of 1.0 mL x min(-1). The detection wavelength was set 340 nm.RESULTOrientin showed a good linear relationship in the range of 8.42-84.2 microg x mL(-1) (r = 0.9999) and the average recovery is 98.3%, RSD is 0.8%. Vitexin showed a good linear relationship in the range of 8.07-80.7 microg x mL(-1) (r = 0.9999) and the average recovery is 102.4%. RSD is 1.7%.CONCLUSIONThe method is sensitive, specific, and accurate with a good repeatability and can be used for the quality control of Trollius chinesis preparation.

China journal of Chinese materia medica

Determination of orientin and vitexin in Trollius chinesis preparation by HPLC

作者: Zu-chao Xu ; Wen Li ; Zhi Liu ; Li Wang ; Yong Huang

Objective To establish a HPLC method for determining orientin and vitexin in Trollius chinesis preparation. Method The separation was carried out on Hypersil ODS column with a mixture of acetonitrile-1% acetic acid solution (15:85) as the mobile phase, at a flow rate of 1.0 mL x min(-1). The detection wavelength was set 340 nm. Result Orientin showed a good linear relationship in the range of 8.42-84.2 microg x mL(-1) (r = 0.9999) and the average recovery is 98.3%, RSD is 0.8%. Vitexin showed a good linear relationship in the range of 8.07-80.7 microg x mL(-1) (r = 0.9999) and the average recovery is 102.4%. RSD is 1.7%. Conclusion The method is sensitive, specific, and accurate with a good repeatability and can be used for the quality control of Trollius chinesis preparation.

Zhongguo Zhongyao Zazhi

Determination of orientin and vitexin in Trollius chinensis preparation by HPLC

作者: Li, Wen ; Huang, Yong ; Liu, Zhi ; Xu, Zuchao ; Wang, Li

An HPLC method for determining orientin and vitexin in Trollius chinensis preparation was presented.The separation was carried out on Hypersil ODS column with a mixture of acetonitrile-1% acetic acid solution (15:85) as the mobile phase at a flow rate of 1.0 mL/min.The detection wavelength was 40 nm.The linear range for orientin was 8.42-84.2 μg/mL , average recovery 98.3%, and RSD 0.8%.For vitexin, the linear range was 8.07-80.7 μg/mL (r = 0.999 9), average recovery 102.4%, and RSD 1.7%.The method is sensitive, accurate, selective, and reproducible, and can be used for the quality control of Trollius chinensis preparation

100 项与贵州一康药业有限公司相关的药物交易

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100 项与贵州一康药业有限公司相关的转化医学

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