Ataturk University

Heart failure (HF) remains a significant health problem despite advances in diagnosis and treatment options. Malnutrition and increased inflammation predict poor disease prognosis. The parameters of the Naples prognostic score (NPS) include albumin, total cholesterol, neutrophil-lymphocyte ratio (NLR), and lymphocyte-monocyte ratio (LMR). We aimed to assess the potential of NPS as a predictor of long-term mortality in patients with HF.

A total of 1728 patients with HF who applied to our center between 2018 and 2022 were included in this study. The NPS was computed and the patients were divided into three groups according to their NPS values as follows: NPS = 0 (Group 1), NPS = 1-2 (Group 2), and NPS = 3-4 (Group 3). We also evaluated the association between NPS value and HF mortality.

The patients were followed for a mean follow-up duration of 30 months. The mortality rate was 8.3% (145 patients). We carried out Model-1 and -2 Cox regression analyses to identify long-term mortality determinants. Model-2 was constructed by adding NPS to Model-1. NPS was significantly associated with HF mortality (Hazard Ratio: 2.194, 95% Confidence Interval: 1.176-4.091, p = 0.014). According to the Kaplan-Meier plot and log-rank analyses, there was a statistically significant difference in the long-term mortality of patients with HF and their NPS values for the entire cohort.

Based on our findings, NPS showed promise as an independent predictor of long-term mortality in individuals with HF.

Taekwondo is a complex martial art that requires speed, balance, agility, and endurance. This study aims to examine the effects of nitrate and L-arginine supplementation on acute aerobic and anaerobic performance, balance, agility, and recovery in elite taekwondo athletes.

This study was conducted as a double-blind, randomized, crossover study with the participation of 15 experienced taekwondo athletes aged 19.06 ± 0.96 years and 8.93 ± 1.27 years of training experience. Participants visited the laboratory a total of nine times, including a practice session and anthropometric measurements. These visits consisted of eight experimental sessions conducted at 72-hour intervals. The experimental sessions were conducted with nitrate, L-arginine, and a combination of both supplements (NIT*L-ARG) and placebo. Nitrate supplementation was provided by homogenizing fresh spinach (837.40 mg/kg), while L-ARG was given as a single dose of 6 g in powder form three hours before exercise.

NIT*L-ARG supplementation significantly improved the anaerobic performance of athletes in Wingate peak power and peak power (w/kg) compared to placebo and in mean power compared to NIT, L-ARG, and PLA. In addition, NIT*L-ARG supplementation significantly improved blood lactate levels and agility performance immediately after Wingate and Shuttle run tests.

The combined intake of NIT*L-ARG was found to be effective in improving aerobic, anaerobic, and agility performances as well as fatigue levels of athletes. It was determined that taking NIT and L-ARG supplements alone contributed to the improvement of improving athletes' performance in Wingate mean power values and subsequent fatigue level compared to PLA.

For both financial and environmental reasons, it is becoming more and more common to investigate recycling waste building materials from construction and demolition (C&D) sites.For the construction of big structures like dams or wide horizontal surfaces like road foundations, roller compacted concrete (RCC) is a unique dry concrete comprised of aggregates, water, and a little amount of cement.A high-volume solid waste-based RCC was prepared in this study, and different contents of recycled aggregate, biomass ash (BA) and polypropylene fiber (PPF) were used.Meanwhile, the mech. properties, durability, microstructure and environmental benefits of eco-friendly RCCs were evaluated.The results showed that the addition of CRA, FRA and BA resulted in a decrease in the mech. properties of RCC.When the full volume of recycled aggregate was used, the 90-d compressive strength of RCC reinforced with 1% PPF could reach 41.53 MPa.Although the dry unit weight of RCC was decreased by the addition of recycled aggregate and BA, its sorptivity coefficient was also increased.Meanwhile, the full-volume solid waste-based RCC exhibited high resistance to chem. attack and freeze-thaw.In addition, proper recycling of recycled aggregates and BA can effectively reduce the cost and carbon footprint of RCC.