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原研机构- |
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最高研发阶段临床3期 |
首次获批国家/地区- |
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Evaluating the Effect of Length of Time on Selective Serotonin Reuptake Inhibitors (SSRIs) on the Response to Psilocybin-assisted Therapy in Individuals With Mild-moderate Major Depressive Disorder (MDD)
This study is an open-label, single-arm, within-subjects design in individuals with mild-moderate Major Depressive Disorder (MDD). All participants will receive a single dose of 25mg of psilocybin in a therapeutic setting. In order to investigate the effects of length of time on SSRI therapy, 30 participants with varying lengths of time on SSRI therapy will be enrolled, stratified into four groups:
Group 1: ≤ 1 year
Group 2: 1 to ≤ 5 years
Group 3: 5 to ≤ 10 years
Group 4: > 10 years
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