The quaternization of (ZCH2CH2)2NR (Z = piperidino) (I) with MeI, EtBr, PrBr, and BuBr was investigated. I (R = Me) (1.5 moles) and 1.0 mole MeI react to give two dimethiodides, m. 181-3° and 224-6°, resp., soluble and slightly soluble in MeOH-EtOH. If 2.0 moles MeI was used, a trimethiodide was obtained, m. 207-9°. Two dimethiodides, m. 176-8° and 218-20°, were also obtained from I (R = Et). In case R = Pr, one monomethiodide, m. 194-6°, and one dimethiodide, m. 231-3°, were formed. However, one monomethiodide, m. 164-6°, and one trimethiodide, m. 193-5°, were isolated if R = Bu. The reaction of I (R = Me) with EtBr, PrBr, or BuBr resulted in only monoquaternary products, m. 180-1°, 213- 14°, and 151-3°, resp.