Prospective Trial Of Osmolar Protocol Solution on Colonoscopy Outcomes and Patient Experience
Fasting is the current standard of care for colonoscopies. Recent changes to anesthesia guidelines have allowed for clear fluids to be provided up to 2 hours before procedures, including colonoscopies.
This study will compare fasting to a 12.5% carbohydrate solution 2 hours before colonoscopy on patient-reported measures of discomfort, hydration, and colon visibility.
The investigators hypothesize that the carbohydrate solution will improve patient-reported measures of discomfort, hydration, and colon visibility.
Coagulopathy of COVID-19: A Pragmatic Randomized Controlled Trial of Therapeutic Anticoagulation Versus Standard Care as a Rapid Response to the COVID-19 Pandemic (RAPID COVID COAG)
Coagulopathy of COVID-19 afflicts approximately 20% of patients with severe COVID-19 and is associated with need for critical care and death. COVID-19 coagulopathy is characterized by elevated D-dimer, an indicator of fibrin formation and clot lysis, and a mildly prolonged prothrombin time, suggestive of coagulation consumption. To date, it seems that COVID-19 coagulopathy manifests with thromboembolism, thus anticoagulation may be of benefit. We propose to conduct a parallel pragmatic multi-centre open-label randomized controlled trial to determine the effect of therapeutic anticoagulation compared to standard care in hospitalized patients admitted for COVID-19 with an elevated D-dimer.
Buprenorphine in the Emergency Department: Buprenorphine Versus Clonidine for Opioid Withdrawal
This is a pilot randomized control trial randomizing patients presenting in opioid withdrawal to the emergency department to receive either one of clonidine (usual standard of care) or buprenorphine for their opioid withdrawal. Primary treatment outcome is attendance at a rapid access addiction medicine clinic within a few days of emergency room presentation. Secondary treatment outcome is treatment status with respect to opioid agonist treatment at one month post emergency room visit.
100 项与 St. Joseph's Health Centre, Toronto 相关的临床结果
0 项与 St. Joseph's Health Centre, Toronto 相关的专利(医药)
2025-05-19·BRITISH JOURNAL OF DERMATOLOGY
Article
作者: Dahlke, Erin ; Hessami-Booshehri, Morvarid ; Rijal, Hibo ; Helal, Shaimaa
Increasing racial, ethnic and religious global diversity of patient populations warrants integration of culturally sensitive care by dermatologists. The Muslim population represents one of interest with traditional practices of covering the skin and scalp that often intersect with dermatological care. Recommendations based on Islamic practices followed by many Muslim men and women including providing third-party chaperones, limiting exposure of preferred religiously covered regions and providing spiritually informed treatment guidelines (oral medications within fasting periods) are described here to inform dermatologists on methods to optimize treatment outcomes in this population. This will allow for dermatologists to provide culturally inclusive and equitable care for their Muslim patients.
2025-01-27·CANADIAN MEDICAL ASSOCIATION JOURNAL
Des antibiothérapies de plus courte durée
Article
作者: Schwartz, Kevin L ; Ivankovic, Maria
2024-12-30·Paediatrics & Child Health
Article
作者: Huber, Joelene ; Freeman, Sloane J ; Cohen-Silver, Justine ; Rasiah, Shajitha ; Andrade, Brendan F ; Rasiah, Saisujani ; Suri, Anjali
Objectives:School-based health centres (SBHCs) provide developmental and mental health care to children with socioeconomic disparities. We piloted a validated behavioural intervention called Coping Power (CP) for children with disruptive behaviour through our SBHC program. The objective of this pilot study was to examine the feasibility of CP in the SBHC setting.
Methods:All parent/caregiver and child dyads enrolled in CP from 2018 to 2019 and 2021 to 2022 were invited to participate in the study. Demographic information and behaviour rating scales were collected at baseline. Feasibility metrics included attendance and satisfaction survey responses.
Results:A total of 31 parent/caregiver-child dyads were included. Approximately 40% of families had an annual income of <$49,999. Regarding attendance, 22/31 children/parent/caregiver dyads (70.9%) missed ≤2 sessions. Thirteen parents/caregivers completed the CP satisfaction survey and indicated that they were either ‘somewhat’ (n = 4) or ‘very satisfied’ (n = 9) with the program. Of the 18 children who completed the satisfaction survey, 13 (72.2%) shared that either the ‘sort of’ or ‘for sure’ group helped them cope with their anger better.
Conclusions:This pilot study found that CP delivered within the SBHCs was feasible. Improving access to CP for disadvantaged children may improve mental health outcomes.
100 项与 St. Joseph's Health Centre, Toronto 相关的药物交易
100 项与 St. Joseph's Health Centre, Toronto 相关的转化医学