预约演示
更新于：2026-10-10
Shanghai Mental Health Center
更新于：2026-10-10
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100 项与 上海市精神卫生中心（上海市心理咨询培训中心） 相关的临床结果
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2027-01-01PSYCHIATRY RESEARCH-NEUROIMAGING
Heart rate fragmentation in psychiatry: across age stages and association with conventional heart rate variability
Article
作者: Su, Min ; Li, ChunBo ; Liu, HaiChun ; Cui, Yin ; Zhang, XinFan ; Zeng, LingYun ; Wei, YanYan ; Xu, LiHua ; Gao, Jin ; Huang, LiYing ; Zhang, Dan ; Jiao, Xiong ; Ye, AiMei ; Ju, MingLiang ; Zhang, TianHong ; Cui, HuiRu ; Xiong, YuXuan ; Yang, YiYi ; Tang, XiaoChen ; Wang, JiJun ; Chai, Hao
BACKGROUND:
Heart rate fragmentation (HRF) reflects disorganized beat-to-beat rhythm dynamics not captured by conventional heart rate variability (HRV). This study characterized age-related HRF patterns in psychiatric patients using the percentage of inflection points (PIP) as the primary index and examined differences by sex and diagnosis, as well as associations with conventional HRV.
METHODS:
We included 3,813 patients with schizophrenia, depressive disorder, anxiety disorder, or sleep disorder across four age groups. Three-minute resting electrocardiograms were used to derive PIP, the percentage of alternating segments (PAS), and the conventional HRV indices RMSSD, SDNN, LF, and HF. Group differences were tested by analysis of covariance. Associations between PIP and HRV were assessed using partial Spearman correlations and multivariable linear regression with covariate adjustment.
RESULTS:
PIP increased across age groups, whereas conventional HRV indices declined (all p < 0.001). Males showed higher PIP than females in adolescence and early adulthood, but not in later adulthood. Diagnosis had a significant main effect on PIP, although between-diagnosis differences were modest, and no diagnosis-by-age interaction was observed. PIP was inversely associated with all HRV indices, most strongly with LnHF (all p < 0.001). PAS showed a similar pattern.
CONCLUSIONS:
HRF was higher in older age groups in this psychiatric sample, showed sex differences that varied across age groups, and displayed limited diagnostic specificity. Its robust inverse association with conventional HRV, particularly HF, suggests partial overlap with traditional HRV and supports fragmentation as a complementary marker of beat-to-beat rhythm organization.
2026-12-01ADVANCES IN PHYSIOLOGY EDUCATION
Revealing the link between critical thinking disposition and learning approaches: a cross-sectional study among Chinese medical students
Article
作者: Fu, Shiyu ; Luo, Ziqiang ; Yang, Luning ; Lin, Yicheng ; Liu, Ziqi ; Xu, Yangting
This study is among the first to examine how deep and surface learning approaches predict CT disposition in Chinese medical students. By integrating the R-SPQ-2F and the CTDI-CV, we not only analyzed the associations between CT dispositions and LA but also developed a regression model explaining 39% of CT variance. Our findings highlight that innovative activities and academic performance moderate the CT-LA relationship, suggesting actionable targets for curriculum reform.
2026-11-01ADDICTIVE BEHAVIORS
Sex-specific temporal symptom networks in gaming disorder − depression comorbidity: longitudinal validation of the I-PACE model
Article
作者: You, Shiqi ; Huang, Chuanning ; Zhao, Min ; Wang, Zipan ; Zhong, Na ; Shan, Haidi ; Wang, Yue ; Li, Shuo
Although gaming disorder (GD) and depression commonly co-occur, no prior study has examined their symptom-level temporal dynamics through a theoretical lens. This longitudinal study employed cross-lagged panel network analysis (CLPN) to examine 3,203 Chinese college students (73.90% male, 26.10% female) across two time points (6-month interval) to validate the sex-specific temporal mechanisms of the I-PACE (Interaction of Person-Affect-Cognition-Execution) model. Bidirectional predictive relationships emerged between GD and depression symptoms, with depression showing stronger predictive stability (89.71% vs 77.27% positive connections). Key bridge symptoms included Psychomotor Agitation (Bridge EI1 = 0.690), Time concealment (BridgeEI1 = 0.499) and Game Anxiety (BridgeEI1 = 0.448). Sex-specific network comparisons revealed largely divergent network structures and non-overlapping centrality profiles (edge correlation: r = 0.15, 49% of edges differing in directionality). In males, psychomotor agitation (Bridge EI = 0.826) and time concealment (Bridge EI = 0.595) emerged as descriptively prominent bridge nodes, whereas in females, social withdrawal served as the primary bridge node (Bridge EI = 0.356). The findings provide empirical validation for sex-specific modifications to the I-PACE model, suggesting sex-specific tailored intervention approaches targeting bridge symptoms may enhance therapeutic efficacy for GD-depression comorbidity.
100 项与 上海市精神卫生中心（上海市心理咨询培训中心） 相关的药物交易
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100 项与 上海市精神卫生中心（上海市心理咨询培训中心） 相关的转化医学
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