In the title compound, C21H21F2N3O4S, the THF ring adopts an envelope conformation with the β-C atom positioned at the flap. The triazole, difluorophenyl and tolyl rings of the various substituents on the THF ring are inclined at 77.88 (12), 83.81 (10) and 81.00 (10)°, resp., to the best-fit mean plane through the five atoms of the THF ring. In the crystal, weak C-H···O and C-H···F hydrogen bonds link the mols. into a three-dimensional structure, with mols. stacked along the a-axis direction.