Critical Pharmaceuticals Ltd.

DUBLIN--( BUSINESS WIRE )--The "Modified Release Neurology Therapeutics" report has been added to ResearchAndMarkets.com's offering. Large pharmaceutical and biotechnology companies are increasingly pursuing in-licensing to offset lower than expected drug development productivity and surging research costs. Data mining technologies, combined with data from genomics, combinational chemistry and outcome-based medicine, provide opportunities to search for new patterns. By using hypertext type tools, companies are finding it possible to build knowledge bases where scientists can link data and ideas to generate insights into new relationships between population groups, diseases, and treatment. For long-acting formulations of Injectable drugs, development collaborations typically follow one of two business models. The majority of projects/products are marked by a contractual relationship between the formulation IP developer/holder and the drug developer. The second notable business model is more ambitious and is defined by formulation IP companies that develop long-acting formulations in-house before licensing the marketing rights to a partner, typically in late stage clinical development or after filing an NDA. This is a more powerful financial model, but has a higher level of risk and requires adequate capitalization to finance drug development into or up to Phase 3 trials. The report provides developers, device designers, healthcare marketers, and supply chain participants with a detailed understanding of the economics, technologies, opportunities for injection devices that are designed for patient self-administration. Provider organization business managers, healthcare administrators and investors will also benefit from this study. The study: Analyzes and evaluates modified release neurology therapeutics products and assesses the market potential for existing and probable future products Analyzes product strategies, technologies and market development issues Provides detailed analysis of neurology market segments, market demographics, and therapeutic strategies Profiles market sector companies, their product development activities, business strategies, and corporate alliances and affiliations Evaluates the impact of economic, technology, and regulatory factors on neurology drug markets As patients live longer and the prevalence and incidence of chronic ailments increase across the general population, drug developers and their delivery device partners are adapting to address what will become a significant market opportunity. Chronic conditions require drug administration over long periods of time, placing a greater emphasis on self-administration. With the shift away from caregiver interaction, drug safety and compliance/adherence become prominent concerns. These concerns, which are not new, are becoming magnified as the number of powerful new drugs reaching the market increases. For healthcare managers and public health officials, one way to address these issues is less frequent dosing. Using formulation technologies designed to modulate the effect of therapeutic substances, drug developers are creating formulations that exhibit extended release profiles. These chemistries include polymers such as polyethylene glycol-complexed (PEGylated), which are used to product encapsulated and coated versions of new APIs. The goal is to address the requirement for patient-dependent, and therefore compliance-sensitive, drug treatment protocols such as multiple dosing through controlled release formulations that provide the desired therapeutic effect with dosing of once-a-day or less. A number of companies - contract research organizations or CROs, - offer a variety of pharmaceutical services to drug developers and marketers, including drug formulation development, niche manufacturing, and pre-clinical evaluation. Formulation development services range from new compounds to modifications of existing products. Some companies offer product modification and line extension services for marketed products facing patent expiration or for products that can benefit from formulation improvements. Modifications of existing products to incorporate improved product characteristics can include enhancement of stability, absorption profiles, taste, and appearance. Product line extensions can include controlled release formulations, as well as new dosage strengths. Product modifications and line extensions can create the opportunity to target new patient populations and improve patient acceptance of the product. Other formulation services offered on a contract basis include investigation of impurities, contaminants and degradation, the updating of mature products to meet current regulatory standards and laboratory validation services. Key Topics Covered: The Neurological Drug Market Dynamics The Trend Toward Self-Administration Route of Administration Innovation in Drug Formulation Neurological Drugs and As-supplied Packaging Human Engineering/Ergonomics Delivering Neurological Drugs via Injection Primary Packaging Innovation in Injectable Device Designs Drug Delivery Device Selection Issues Therapeutic Demand Drivers Key Market Factors MR Neurological Product Analysis Proprietary Formulation Technology ChroniJect (Oakwood Laboratories/PharmaSophia) CriticalMix (Critical Pharmaceuticals) Depofoam (Pacira) FluidCrystal (Camarus) LinkeRx (Alkermes) Medisorb (Alkermes) Medusa (Recipharm/Avadel) Nanocrystals (Alkermes) Optisomes (Talon/Spectrum) PolyActive (Octoplus) Q-Sphera (Midatech Pharma) SABER/SAIB (DURECT) SynBiosys (Innocore) TransCon (Ascendis) Physical Process Control Methods Supercritical Fluid SCF for Nanoparticle Formulations Formulplex (Supercritical Solutions) Ferro SCF extraction of emulsions (SFEE) Stability Administration Factors Therapeutic Market Sectors Schizophrenia Bipolar Disorder Market Sector Analysis and Forecasts Key Market Factors Economic Factors Technology Factors Regulatory Factors Risk Factors Forecasts and Market Data Company Profiles Alkermes Amylin AntriaBio Ascendis Pharma AstraZeneca Aurobundo Avadel Biomarin Camurus Critical Pharmaceuticals DURECT Eli Lilly Enzon Ipsen Janssen NanOlogy Novartis Oakwood Laboratories/PharmaSophia OctoPlus Pacira PhaseBio Pharmaceuticals Recipharm AB Roche Sanofi Taiwan Liposome Company Xbrane Bipharma For more information about this report visit https://www.researchandmarkets.com/r/z14n0x About ResearchAndMarkets.com ResearchAndMarkets.com is the world's leading source for international market research reports and market data. We provide you with the latest data on international and regional markets, key industries, the top companies, new products and the latest trends.

DUBLIN, Feb. 14, 2024 /PRNewswire/ -- The "Modified Release Neurology Therapeutics" report has been added to ResearchAndMarkets.com's offering. Large pharmaceutical and biotechnology companies are increasingly pursuing in-licensing to offset lower than expected drug development productivity and surging research costs. Data mining technologies, combined with data from genomics, combinational chemistry and outcome-based medicine, provide opportunities to search for new patterns. By using hypertext type tools, companies are finding it possible to build knowledge bases where scientists can link data and ideas to generate insights into new relationships between population groups, diseases, and treatment. For long-acting formulations of Injectable drugs, development collaborations typically follow one of two business models. The majority of projects/products are marked by a contractual relationship between the formulation IP developer/holder and the drug developer. The second notable business model is more ambitious and is defined by formulation IP companies that develop long-acting formulations in-house before licensing the marketing rights to a partner, typically in late stage clinical development or after filing an NDA. This is a more powerful financial model, but has a higher level of risk and requires adequate capitalization to finance drug development into or up to Phase 3 trials. The report provides developers, device designers, healthcare marketers, and supply chain participants with a detailed understanding of the economics, technologies, opportunities for injection devices that are designed for patient self-administration. Provider organization business managers, healthcare administrators and investors will also benefit from this study. The study: Analyzes and evaluates modified release neurology therapeutics products and assesses the market potential for existing and probable future products Analyzes product strategies, technologies and market development issues Provides detailed analysis of neurology market segments, market demographics, and therapeutic strategies Profiles market sector companies, their product development activities, business strategies, and corporate alliances and affiliations Evaluates the impact of economic, technology, and regulatory factors on neurology drug markets As patients live longer and the prevalence and incidence of chronic ailments increase across the general population, drug developers and their delivery device partners are adapting to address what will become a significant market opportunity. Chronic conditions require drug administration over long periods of time, placing a greater emphasis on self-administration. With the shift away from caregiver interaction, drug safety and compliance/adherence become prominent concerns. These concerns, which are not new, are becoming magnified as the number of powerful new drugs reaching the market increases. For healthcare managers and public health officials, one way to address these issues is less frequent dosing. Using formulation technologies designed to modulate the effect of therapeutic substances, drug developers are creating formulations that exhibit extended release profiles. These chemistries include polymers such as polyethylene glycol-complexed (PEGylated), which are used to product encapsulated and coated versions of new APIs. The goal is to address the requirement for patient-dependent, and therefore compliance-sensitive, drug treatment protocols such as multiple dosing through controlled release formulations that provide the desired therapeutic effect with dosing of once-a-day or less. A number of companies - contract research organizations or CROs, - offer a variety of pharmaceutical services to drug developers and marketers, including drug formulation development, niche manufacturing, and pre-clinical evaluation. Formulation development services range from new compounds to modifications of existing products. Some companies offer product modification and line extension services for marketed products facing patent expiration or for products that can benefit from formulation improvements. Modifications of existing products to incorporate improved product characteristics can include enhancement of stability, absorption profiles, taste, and appearance. Product line extensions can include controlled release formulations, as well as new dosage strengths. Product modifications and line extensions can create the opportunity to target new patient populations and improve patient acceptance of the product. Other formulation services offered on a contract basis include investigation of impurities, contaminants and degradation, the updating of mature products to meet current regulatory standards and laboratory validation services. Key Topics Covered: The Neurological Drug Market Dynamics The Trend Toward Self-Administration Route of Administration Innovation in Drug Formulation Neurological Drugs and As-supplied Packaging Human Engineering/Ergonomics Delivering Neurological Drugs via Injection Primary Packaging Innovation in Injectable Device Designs Drug Delivery Device Selection Issues Therapeutic Demand Drivers Key Market Factors MR Neurological Product Analysis Proprietary Formulation Technology ChroniJect (Oakwood Laboratories/PharmaSophia) CriticalMix (Critical Pharmaceuticals) Depofoam (Pacira) FluidCrystal (Camarus) LinkeRx (Alkermes) Medisorb (Alkermes) Medusa (Recipharm/Avadel) Nanocrystals (Alkermes) Optisomes (Talon/Spectrum) PolyActive (Octoplus) Q-Sphera (Midatech Pharma) SABER/SAIB (DURECT) SynBiosys (Innocore) TransCon (Ascendis) Physical Process Control Methods Supercritical Fluid SCF for Nanoparticle Formulations Formulplex (Supercritical Solutions) Ferro SCF extraction of emulsions (SFEE) Stability Administration Factors Therapeutic Market Sectors Schizophrenia Bipolar Disorder Market Sector Analysis and Forecasts Key Market Factors Economic Factors Technology Factors Regulatory Factors Risk Factors Forecasts and Market Data Company Profiles Alkermes Amylin AntriaBio Ascendis Pharma AstraZeneca Aurobundo Avadel Biomarin Camurus Critical Pharmaceuticals DURECT Eli Lilly Enzon Ipsen Janssen NanOlogy Novartis Oakwood Laboratories/PharmaSophia OctoPlus Pacira PhaseBio Pharmaceuticals Recipharm AB Roche Sanofi Taiwan Liposome Company Xbrane Bipharma For more information about this report visit About ResearchAndMarkets.com ResearchAndMarkets.com is the world's leading source for international market research reports and market data. We provide you with the latest data on international and regional markets, key industries, the top companies, new products and the latest trends. Media Contact: Research and Markets Laura Wood, Senior Manager [email protected] For E.S.T Office Hours Call +1-917-300-0470 For U.S./CAN Toll Free Call +1-800-526-8630 For GMT Office Hours Call +353-1-416-8900 U.S. Fax: 646-607-1907 Fax (outside U.S.): +353-1-481-1716 Logo: SOURCE Research and Markets

DUBLIN, Jan. 15, 2024 /PRNewswire/ -- The "Chronic Disease Markets for Sustained Released Injectables" report has been added to ResearchAndMarkets.com's offering. The report provides a comprehensive evaluation and analysis of the technology, products and participants providing the driving force behind this evolving segment of the healthcare sector. The study is designed to provide drug company decision makers, drug delivery developers, device designers, healthcare marketers, and supply chain participants with a detailed understanding of the economics, technologies, disease segments, and commercial opportunities for chronic disease markets for sustained release injectables. Provider organization business managers, healthcare administrators and investors will also benefit from this study. Evolving Engineered Solutions Chronic conditions require drug administration over long periods of time, placing a greater emphasis on self-administration. With the shift away from caregiver interaction, drug safety and compliance/adherence become prominent concerns. These concerns, which are not new, are becoming magnified as the number of powerful new drugs reaching the market increases. For healthcare managers and public health officials, one way to address these issues is less frequent dosing. Using formulation technologies designed to modulate the effect of therapeutic substances, drug developers are creating formulations that exhibit extended-release profiles. These chemistries include polymers such as polyethylene glycol-complexed (PEGylated), which are used to product encapsulated and coated versions of new APIs. The goal is to address the requirement for patient-dependent, and therefore compliance-sensitive, drug treatment protocols such as multiple dosing through controlled release formulations that provide the desired therapeutic effect with dosing of once-a-day or less. What You Will Learn What are the marketed sustained release injectable drug products, what sustained release formulation technologies are used, and who markets them? What are the major factors driving sustained release injectable drug demand? What sustained release injectable drug candidates are in late-stage clinical development and what is their potential impact? How important are drug developer-formulation technologist relationships in the sustained release market segment, and what are the key alliances in the industry? What are the essential formulation factors, delivery device selection issues, related technology factors and market development issues for sustained release injectable drug products? In what therapeutic market segments do sustained release injectables compete? What is their market share today? What will it be in 2028? What is their expected growth rate? What are the significant economic, technology, and regulatory factors affecting the market for sustained release injectables? Key Topics Covered: Injectable Drug Market Dynamics The Trend toward Self-Administration Injectable Drug Formulation Technology Innovation in Injectable Device Designs Therapeutic Demand Drivers Market Factors Competitive Landscape Risk Factors Sustained Release - Branded Formulation Technologies Biodegradable Polymers Branded SR Formulation Technologies Physical Process Control Methods Sustained Release Injectables - Development Factors Formulation Factors Stability Lyophilization Packaging Administration Factors SR Injectables - Product Analysis & Market Sector Forecasts Addiction Naltrexone Diabetes Exenatide Infectious Disease Interferon Hormone Deficiency Estradiol Somatropin Testosterone Metabolic Diseases Acromegaly Neurology Oncology Leukemia Lymphoma Cytarabine Prostate Pain Management Reproductive Health Fertility Endometriosis Market Profiles Companies Mentioned Alkermes Amylin AntriaBio Ascendis Pharma AstraZeneca Aurobundo Avadel Biomarin Camurus Critical Pharmaceuticals DURECT Eli Lilly Enzon Ipsen Janssen NanOlogy Novartis OctoPlus Oakwood Laboratories/PharmaSophia Pacira PhaseBio Pharmaceuticals Recipharm AB Roche Sanofi Taiwan Liposome Company Xbrane Bipharma For more information about this report visit About ResearchAndMarkets.com ResearchAndMarkets.com is the world's leading source for international market research reports and market data. We provide you with the latest data on international and regional markets, key industries, the top companies, new products and the latest trends. Media Contact: Research and Markets Laura Wood, Senior Manager [email protected] For E.S.T Office Hours Call +1-917-300-0470 For U.S./CAN Toll Free Call +1-800-526-8630 For GMT Office Hours Call +353-1-416-8900 U.S. Fax: 646-607-1907 Fax (outside U.S.): +353-1-481-1716 Logo: SOURCE Research and Markets