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1

项与 Cyto Therapeutics Pty Ltd. 相关的药物

ISC hpNSC(Duke University/International Stem Cell)

靶点-

作用机制

多巴胺能细胞替代物 [+1]

在研机构

Tulane University Hospital & Clinic [+1]

原研机构

Duke University [+1]

在研适应症

脑损伤 [+1]

非在研适应症

创伤性脑损伤 [+1]

最高研发阶段临床前

首次获批国家/地区-

首次获批日期-

1

项与 Cyto Therapeutics Pty Ltd. 相关的临床试验

NCT02452723 / Unknown status临床1期

A Single Arm, Open-Label Phase 1 Study to Evaluate the Safety and Tolerability of ISC-hpNSC Injected Into the Striatum and Substantia Nigra of Patients With Parkinson's Disease

This study will evaluate the safety of an investigational cell transplantation therapy, ISC-hpNSC, in patients with Parkinson's disease. All patients will receive the therapy, which consists of human neural stem cells. Three dose levels will be examined in the study.

开始日期2016-07-01

申办/合作机构

Cyto Therapeutics Pty Ltd.

100 项与 Cyto Therapeutics Pty Ltd. 相关的临床结果

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0 项与 Cyto Therapeutics Pty Ltd. 相关的专利（医药）

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1

项与 Cyto Therapeutics Pty Ltd. 相关的文献（医药）

Design considerations for the in vivo stability of hollow fiber based cell encapsulation devices.

作者: Rein, D. ; Shoichet, M. ; Gunrud, T.

An understanding of the in vivo stability requirements is essential in the design of hollow fiber based devices for cell encapsulation.The primary function of a cell encapsulation device is to maintain graft tissue viability and function, maintain a controlled delivery of the therapeutic agent, and allow for retrieval at any point during the treatment.Device parameters influencing cell viability include the capsule microenvironment, the membrane permselectivity, and the membrane outer morphol.Retrievability is determined by the chem. and mech. stability of the device components.The present work will evaluate the in vivo stability of a PAN/PVC hollow fiber membrane, and examine several methods to improve the retrievability of cell encapsulation devices.

100 项与 Cyto Therapeutics Pty Ltd. 相关的药物交易

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100 项与 Cyto Therapeutics Pty Ltd. 相关的转化医学

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