Delving into the Latest Updates on RPG Life Sciences Ltd. with Synapse

A Multicenter, Randomized, Open Label, Two Treatment, Two Period, Two Sequence, Single-Dose, Two-way, Crossover, Bioequivalence, Pilot Study to Evaluate the Bioequivalence of Azathioprine Tablets USP 50mg of RPG Life Sciences Compared to ImuranÂ® 50 mg Tablets of Prometheus Laboratories Inc., USA in Adult Rheumatoid Arthritis Patients Under Fasting Condition

开始日期2017-10-16

申办/合作机构

RPG Life Sciences Ltd.

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7

项与 RPG Life Sciences Ltd. 相关的文献（医药）

International Journal of Current Research

A comparative study for efficacy of Povidone iodine in combination with Ornidazole and Metronidazole in anaerobic isolates

作者: Bhalerao, Mangesh ; Musale, Rajendra ; Vedak, Tejal ; Siingh, Satessh ; Vyas, Bhasker ; Trivedi, Vandit ; Kulkarni, Namrata

Background: The majority of infected wounds are polymicrobial and their treatment is complicated owing to relatively slow growth of organisms and growing resistance of anaerobic bacteria to antimicrobial agents.Hence, the present study was initiated to assess the efficacy of Povidone iodine alone and in combination with Ornidazole and Metronidazole in anaerobic isolates.Methods: Brucella blood agar plates were inoculated with suspension of anaerobic clin. isolates of Peptostreptococcus magnus, Clostridium perfringens, and Bacteroides fragilis.After solidification, 100 μL drug solutions of each antimicrobial agent were added, incubated in anaerobic conditions.Zone of inhibitions were measured after 7-9 days to determine min. inhibitory concentrationResults: Combination of Povidone iodine 5% and Ornidazole 1% was the most effective combination in inhibiting the growth of Bacteroides fragilis and Clostridium perfringens whereas the combination of Povidone iodine 5% and Metronidazole 1% was more effective in inhibiting the growth of Peptostreptococcus magnus than Povidone iodine alone / other drug combinations.Conclusion: The present study reveals that addition of Ornidazole or Metronidazole to Povidone iodine was more effective, than Povidone iodine alone, in inhibiting the growth of all tested anaerobic bacteria namely Bacteroides fragilis, Clostridium perfringens, and Peptostreptococcus magnus.

Eastern Pharmacist

Expiration dating

作者: Gattani, O. R.

A review with 5 references on expiration dates for drug dosage forms, shelf-life, factors affecting the stability, storage conditions, stability testing, methods for calculating shelf-lives, etc.

JOURNAL OF CLINICAL AND DIAGNOSTIC RESEARCH

Precision Medicine: Emerging Trends in Cancer Therapy

作者: Badwaik, Rahul

A review.Every individual has a different genetic make-up; even the genetic alterations are different in the same type of cancer.This demands specific and personalised treatment for the individual.Thus, studying the patient's genetic and clin. profile is the foundation for precision medicine.With the developing technologies and newer mol. tools, it has become easy to select a target-specific treatment based on the genetic makeup of an individual.More individualised approach through precision medicines will not only help in treating cancer but shall negate the scope of early detection with the advanced screening techniques and might also aid in preventing them.In this review, author discuss different aspects of precision medicine in cancer therapy.

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