Herein, the synthesis of multifunctional engineered GOs with the structure of GO@Fe3O4-ligands-CdTe quantum dots (QDs) by an environment-friendly aqueous method was reported. l-cystein (Cys), 3-trimethoxysilyl-propanethiol (TMSP), and glutathione (GSH) were selected as ligands.The as-prepared GO@Fe3O4-ligands-CdTe QDs hybrid nanostructures were characterized by different methods.The findings indicate that the nanocomposites of GO@Fe3O4-ligands-CdTe QDs demonstrate superparamagnetic properties at room temperatureThe saturation magnetization values for GO@Fe3O4, GO@Fe3O4-Cys-CdTe, GO@Fe3O4-GSH-CdTe, and GO@Fe3O4-TMSP-CdTe, are 25, 14, 16, and 2 emu g-1, resp.These nanocomposites show stable and strong luminescence at 580-600 nm.The magnetic nanostructures also reveal the absorption wavelength at 300-490 nm.Using TMSP ligand as a bridge between QDs and magnetic GOs, the luminescence of the nanostructure has not decreased much compared to CdTe QDs.The use of Cys ligand preserves the saturation magnetism of the nanocomposite more than magnetic GO, and the dispersed nanostructure is stable in water.Furthermore, the transverse and longitudinal optical (TO and LO) phonon modes of prepared GO@Fe3O4-ligands-CdTe QDs were obtained by Kramers-Kronig (KK) relations based on fourier-transform IR (FTIR) spectroscopy.The Z-scan results show that the type of used ligand has a great effect on the nonlinear optical (NLO) properties of the final product.The largest NLO parameters are related to GO@Fe3O4- TMSP -CdTe QDs, and the values of nonlinear absorption coefficient and nonlinear refractive index were obtained as 2.17 x 10-3(cm/W) and10.27 x 10-8(cm2/W), resp.As a result, GO@Fe3O4-ligands-CdTe QDs nanostructures can be considered as promising multifunctional nanostructures for various biomedical applications and NLO devices.