I.p. administration of pyridoxine-pyrrolidonecarboxylate mixture (metadoxine) [74536-44-0] (0.5 mg/g) to rats increased hepatic ATP [56-65-5] levels to a maximum of 1.55-fold the control value. Incorporation of 14C from glycine-14C into ATP and into the total adenylate pool was also stimulation by metadoxine.