别名 Bagpipe homeobox protein homolog 1、BAPX1、Homeobox protein NK-3 homolog B + [5] |
简介 Transcriptional repressor that acts as a negative regulator of chondrocyte maturation. PLays a role in distal stomach development; required for proper antral-pyloric morphogenesis and development of antral-type epithelium. In concert with GSC, defines the structural components of the middle ear; required for tympanic ring and gonium development and in the regulation of the width of the malleus (By similarity). |
靶点 |
作用机制 NKX3-2 modulators [+1] |
原研机构 |
非在研适应症- |
最高研发阶段临床1/2期 |
首次获批国家/地区- |
首次获批日期1800-01-20 |
开始日期2024-11-15 |
申办/合作机构 |
开始日期2023-03-16 |
申办/合作机构 |
开始日期2022-03-17 |